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11 similar compounds to monomer 50424850

Compile data set for download or QSAR
Wt: 379.5
BDBM50424852
Wt: 351.4
BDBM50424853
Wt: 365.4
BDBM50424854
Wt: 351.4
BDBM50424855
Wt: 337.4
BDBM50424856
Wt: 339.4
BDBM50424857
Wt: 311.4
BDBM50424858
Wt: 297.3
BDBM50424859
Wt: 325.4
BDBM50424860
Purchase
Wt: 365.4
BDBM50424867
Wt: 355.4
BDBM50424873

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50424852,50424853,50424854,50424855,50424856,50424857,50424858,50424859,50424860,50424867,50424873   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424852
PNG
(CHEMBL2315465)
Show SMILES C(Oc1ccccc1)c1nnc(SCC2CCCCC2)n1-c1ccccc1
Show InChI InChI=1S/C22H25N3OS/c1-4-10-18(11-5-1)17-27-22-24-23-21(16-26-20-14-8-3-9-15-20)25(22)19-12-6-2-7-13-19/h2-3,6-9,12-15,18H,1,4-5,10-11,16-17H2
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n/an/a>3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424853
PNG
(CHEMBL2315464)
Show SMILES C(Oc1ccccc1)c1nnc(SCC2CCC2)n1-c1ccccc1
Show InChI InChI=1S/C20H21N3OS/c1-3-10-17(11-4-1)23-19(14-24-18-12-5-2-6-13-18)21-22-20(23)25-15-16-8-7-9-16/h1-6,10-13,16H,7-9,14-15H2
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n/an/a 1.15E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424854
PNG
(CHEMBL2315463)
Show SMILES C(Oc1ccccc1)c1nnc(SC2CCCCC2)n1-c1ccccc1
Show InChI InChI=1S/C21H23N3OS/c1-4-10-17(11-5-1)24-20(16-25-18-12-6-2-7-13-18)22-23-21(24)26-19-14-8-3-9-15-19/h1-2,4-7,10-13,19H,3,8-9,14-16H2
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n/an/a 960n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424855
PNG
(CHEMBL2315462)
Show SMILES C(Oc1ccccc1)c1nnc(SC2CCCC2)n1-c1ccccc1
Show InChI InChI=1S/C20H21N3OS/c1-3-9-16(10-4-1)23-19(15-24-17-11-5-2-6-12-17)21-22-20(23)25-18-13-7-8-14-18/h1-6,9-12,18H,7-8,13-15H2
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n/an/a 720n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424856
PNG
(CHEMBL2315461)
Show SMILES C(Oc1ccccc1)c1nnc(SC2CCC2)n1-c1ccccc1
Show InChI InChI=1S/C19H19N3OS/c1-3-8-15(9-4-1)22-18(14-23-16-10-5-2-6-11-16)20-21-19(22)24-17-12-7-13-17/h1-6,8-11,17H,7,12-14H2
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n/an/a 960n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424873
PNG
(CHEMBL2315778)
Show SMILES COc1ccc(cc1)-n1c(COc2ccccc2)nnc1SC(C)C
Show InChI InChI=1S/C19H21N3O2S/c1-14(2)25-19-21-20-18(13-24-17-7-5-4-6-8-17)22(19)15-9-11-16(23-3)12-10-15/h4-12,14H,13H2,1-3H3
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n/an/a>3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424858
PNG
(CHEMBL2315459)
Show SMILES CCSc1nnc(COc2ccccc2)n1-c1ccccc1
Show InChI InChI=1S/C17H17N3OS/c1-2-22-17-19-18-16(13-21-15-11-7-4-8-12-15)20(17)14-9-5-3-6-10-14/h3-12H,2,13H2,1H3
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n/an/a 9.92E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424859
PNG
(CHEMBL2315813)
Show SMILES CSc1nnc(COc2ccccc2)n1-c1ccccc1
Show InChI InChI=1S/C16H15N3OS/c1-21-16-18-17-15(12-20-14-10-6-3-7-11-14)19(16)13-8-4-2-5-9-13/h2-11H,12H2,1H3
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n/an/a>3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424860
PNG
(CHEMBL2315812)
Show SMILES CC(C)Sc1nnc(COc2ccccc2)n1-c1ccccc1
Show InChI InChI=1S/C18H19N3OS/c1-14(2)23-18-20-19-17(13-22-16-11-7-4-8-12-16)21(18)15-9-5-3-6-10-15/h3-12,14H,13H2,1-2H3
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n/an/a 2.69E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424867
PNG
(CHEMBL2315784)
Show SMILES Cc1cccc(c1)-n1c(COc2ccccc2)nnc1SC1CCCC1
Show InChI InChI=1S/C21H23N3OS/c1-16-8-7-9-17(14-16)24-20(15-25-18-10-3-2-4-11-18)22-23-21(24)26-19-12-5-6-13-19/h2-4,7-11,14,19H,5-6,12-13,15H2,1H3
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n/an/a 2.78E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair
Valosin containing protein, p97 subunit


(Homo sapiens (Human))
BDBM50424857
PNG
(CHEMBL2315460)
Show SMILES CC(C)CSc1nnc(COc2ccccc2)n1-c1ccccc1
Show InChI InChI=1S/C19H21N3OS/c1-15(2)14-24-19-21-20-18(13-23-17-11-7-4-8-12-17)22(19)16-9-5-3-6-10-16/h3-12,15H,13-14H2,1-2H3
PDB

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PubMed
n/an/a 1.29E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...


J Med Chem 56: 437-50 (2013)


Article DOI: 10.1021/jm3013213
BindingDB Entry DOI: 10.7270/Q21Z45QK
More data for this
Ligand-Target Pair