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10 similar compounds to monomer 50440144

Wt: 421.5
BDBM50440140
Wt: 407.4
BDBM50440141
Wt: 407.4
BDBM50440142
Wt: 421.5
BDBM50440143
Wt: 421.5
BDBM50440145
Wt: 407.4
BDBM50440146
Wt: 407.4
BDBM50440147
Wt: 392.4
BDBM50440158
Wt: 345.4
BDBM50440168
Purchase
Wt: 389.4
BDBM50440169
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50440140,50440141,50440142,50440143,50440145,50440146,50440147,50440158,50440168,50440169   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Deoxycytidine kinase


(Homo sapiens)
BDBM50440140
PNG
(CHEMBL2426588)
Show SMILES COc1ccc(cc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)c(C)s1
Show InChI InChI=1S/C18H20FN5O2S2/c1-10-12(9-27-18-23-15(20)8-16(21)24-18)22-17(28-10)11-3-4-13(25-2)14(7-11)26-6-5-19/h3-4,7-8H,5-6,9H2,1-2H3,(H4,20,21,23,24)
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9.5n/an/an/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK (unknown origin) by steady-state kinetic assay


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Deoxycytidine kinase


(Homo sapiens)
BDBM50440158
PNG
(CHEMBL2426595)
Show SMILES Cc1ccc(cc1OCCF)-c1nc(CSc2nc(N)nc(N)n2)cs1
Show InChI InChI=1S/C16H17FN6OS2/c1-9-2-3-10(6-12(9)24-5-4-17)13-20-11(7-25-13)8-26-16-22-14(18)21-15(19)23-16/h2-3,6-7H,4-5,8H2,1H3,(H4,18,19,21,22,23)
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n/an/a 1.92E+3n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Homo sapiens)
BDBM50440142
PNG
(CHEMBL2426586)
Show SMILES COc1ccc(OCCF)cc1-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H18FN5O2S2/c1-24-13-3-2-11(25-5-4-18)6-12(13)16-21-10(8-26-16)9-27-17-22-14(19)7-15(20)23-17/h2-3,6-8H,4-5,9H2,1H3,(H4,19,20,22,23)
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n/an/a 1.04E+3n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Homo sapiens)
BDBM50440143
PNG
(CHEMBL2426585)
Show SMILES COc1ccc(cc1OCCCF)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C18H20FN5O2S2/c1-25-13-4-3-11(7-14(13)26-6-2-5-19)17-22-12(9-27-17)10-28-18-23-15(20)8-16(21)24-18/h3-4,7-9H,2,5-6,10H2,1H3,(H4,20,21,23,24)
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n/an/a 197n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Homo sapiens)
BDBM50440145
PNG
(CHEMBL2426583)
Show SMILES CCOc1ccc(cc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C18H20FN5O2S2/c1-2-25-13-4-3-11(7-14(13)26-6-5-19)17-22-12(9-27-17)10-28-18-23-15(20)8-16(21)24-18/h3-4,7-9H,2,5-6,10H2,1H3,(H4,20,21,23,24)
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n/an/a 251n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Homo sapiens)
BDBM50440146
PNG
(CHEMBL2426582)
Show SMILES COc1ccc(cc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H18FN5O2S2/c1-24-12-3-2-10(6-13(12)25-5-4-18)16-21-11(8-26-16)9-27-17-22-14(19)7-15(20)23-17/h2-3,6-8H,4-5,9H2,1H3,(H4,19,20,22,23)
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n/an/a 230n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Deoxycytidine kinase


(Homo sapiens)
BDBM50440147
PNG
(CHEMBL2426581)
Show SMILES COc1cc(ccc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H18FN5O2S2/c1-24-13-6-10(2-3-12(13)25-5-4-18)16-21-11(8-26-16)9-27-17-22-14(19)7-15(20)23-17/h2-3,6-8H,4-5,9H2,1H3,(H4,19,20,22,23)
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n/an/a 421n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Mus musculus)
BDBM50440158
PNG
(CHEMBL2426595)
Show SMILES Cc1ccc(cc1OCCF)-c1nc(CSc2nc(N)nc(N)n2)cs1
Show InChI InChI=1S/C16H17FN6OS2/c1-9-2-3-10(6-12(9)24-5-4-17)13-20-11(7-25-13)8-26-16-22-14(18)21-15(19)23-16/h2-3,6-7H,4-5,8H2,1H3,(H4,18,19,21,22,23)
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n/an/a 3.20E+3n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Mus musculus)
BDBM50440140
PNG
(CHEMBL2426588)
Show SMILES COc1ccc(cc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)c(C)s1
Show InChI InChI=1S/C18H20FN5O2S2/c1-10-12(9-27-18-23-15(20)8-16(21)24-18)22-17(28-10)11-3-4-13(25-2)14(7-11)26-6-5-19/h3-4,7-8H,5-6,9H2,1-2H3,(H4,20,21,23,24)
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n/an/a 35n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Deoxycytidine kinase


(Mus musculus)
BDBM50440141
PNG
(CHEMBL2426587)
Show SMILES COc1cc(OCCF)ccc1-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H18FN5O2S2/c1-24-13-6-11(25-5-4-18)2-3-12(13)16-21-10(8-26-16)9-27-17-22-14(19)7-15(20)23-17/h2-3,6-8H,4-5,9H2,1H3,(H4,19,20,22,23)
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n/an/a 5.47E+3n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Mus musculus)
BDBM50440142
PNG
(CHEMBL2426586)
Show SMILES COc1ccc(OCCF)cc1-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H18FN5O2S2/c1-24-13-3-2-11(25-5-4-18)6-12(13)16-21-10(8-26-16)9-27-17-22-14(19)7-15(20)23-17/h2-3,6-8H,4-5,9H2,1H3,(H4,19,20,22,23)
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n/an/a 1.45E+3n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Mus musculus)
BDBM50440143
PNG
(CHEMBL2426585)
Show SMILES COc1ccc(cc1OCCCF)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C18H20FN5O2S2/c1-25-13-4-3-11(7-14(13)26-6-2-5-19)17-22-12(9-27-17)10-28-18-23-15(20)8-16(21)24-18/h3-4,7-9H,2,5-6,10H2,1H3,(H4,20,21,23,24)
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n/an/a 330n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Mus musculus)
BDBM50440145
PNG
(CHEMBL2426583)
Show SMILES CCOc1ccc(cc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C18H20FN5O2S2/c1-2-25-13-4-3-11(7-14(13)26-6-5-19)17-22-12(9-27-17)10-28-18-23-15(20)8-16(21)24-18/h3-4,7-9H,2,5-6,10H2,1H3,(H4,20,21,23,24)
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n/an/a 513n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Mus musculus)
BDBM50440146
PNG
(CHEMBL2426582)
Show SMILES COc1ccc(cc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H18FN5O2S2/c1-24-12-3-2-10(6-13(12)25-5-4-18)16-21-11(8-26-16)9-27-17-22-14(19)7-15(20)23-17/h2-3,6-8H,4-5,9H2,1H3,(H4,19,20,22,23)
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n/an/a 538n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Deoxycytidine kinase


(Mus musculus)
BDBM50440147
PNG
(CHEMBL2426581)
Show SMILES COc1cc(ccc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H18FN5O2S2/c1-24-13-6-10(2-3-12(13)25-5-4-18)16-21-11(8-26-16)9-27-17-22-14(19)7-15(20)23-17/h2-3,6-8H,4-5,9H2,1H3,(H4,19,20,22,23)
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n/an/a 808n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Mus musculus)
BDBM50440168
PNG
(CHEMBL2426577)
Show SMILES COc1cccc(c1)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C15H15N5OS2/c1-21-11-4-2-3-9(5-11)14-18-10(7-22-14)8-23-15-19-12(16)6-13(17)20-15/h2-7H,8H2,1H3,(H4,16,17,19,20)
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n/an/a 1.67E+3n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Mus musculus)
BDBM50440169
PNG
(CHEMBL2426578)
Show SMILES CCOc1ccc(cc1OC)-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H19N5O2S2/c1-3-24-12-5-4-10(6-13(12)23-2)16-20-11(8-25-16)9-26-17-21-14(18)7-15(19)22-17/h4-8H,3,9H2,1-2H3,(H4,18,19,21,22)
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n/an/a 1.12E+3n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
Deoxycytidine kinase


(Homo sapiens)
BDBM50440140
PNG
(CHEMBL2426588)
Show SMILES COc1ccc(cc1OCCF)-c1nc(CSc2nc(N)cc(N)n2)c(C)s1
Show InChI InChI=1S/C18H20FN5O2S2/c1-10-12(9-27-18-23-15(20)8-16(21)24-18)22-17(28-10)11-3-4-13(25-2)14(7-11)26-6-5-19/h3-4,7-8H,5-6,9H2,1-2H3,(H4,20,21,23,24)
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n/an/a 18n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Deoxycytidine kinase


(Homo sapiens)
BDBM50440141
PNG
(CHEMBL2426587)
Show SMILES COc1cc(OCCF)ccc1-c1nc(CSc2nc(N)cc(N)n2)cs1
Show InChI InChI=1S/C17H18FN5O2S2/c1-24-13-6-11(25-5-4-18)2-3-12(13)16-21-10(8-26-16)9-27-17-22-14(19)7-15(20)23-17/h2-3,6-8H,4-5,9H2,1H3,(H4,19,20,22,23)
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n/an/a 2.37E+3n/an/an/an/an/an/a



California NanoSystems Institute

Curated by ChEMBL


Assay Description
Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake


J Med Chem 56: 6696-708 (2013)

More data for this
Ligand-Target Pair