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3 similar compounds to monomer 50442703

Compile data set for download or QSAR
Wt: 310.3
BDBM50442704
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Wt: 220.1
BDBM50442705
Wt: 220.1
BDBM50442714
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50442704,50442705,50442714   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monocarboxylate transporter 4


(Homo sapiens (Human))
BDBM50442704
PNG
(CHEMBL2442506)
Show SMILES Cc1c(C(O)=O)c(=O)oc2cc(OCc3ccccc3)ccc12
Show InChI InChI=1S/C18H14O5/c1-11-14-8-7-13(22-10-12-5-3-2-4-6-12)9-15(14)23-18(21)16(11)17(19)20/h2-9H,10H2,1H3,(H,19,20)
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Institut de Recherche Exp£rimentale et Clinique (IREC)

Curated by ChEMBL


Assay Description
Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...


Bioorg Med Chem 21: 7107-17 (2013)


Article DOI: 10.1016/j.bmc.2013.09.010
BindingDB Entry DOI: 10.7270/Q2H133G8
More data for this
Ligand-Target Pair
Monocarboxylate transporter 4


(Homo sapiens (Human))
BDBM50442714
PNG
(CHEMBL1830821)
Show SMILES COc1ccc2cc(C(O)=O)c(=O)oc2c1
Show InChI InChI=1S/C11H8O5/c1-15-7-3-2-6-4-8(10(12)13)11(14)16-9(6)5-7/h2-5H,1H3,(H,12,13)
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



Institut de Recherche Exp£rimentale et Clinique (IREC)

Curated by ChEMBL


Assay Description
Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...


Bioorg Med Chem 21: 7107-17 (2013)


Article DOI: 10.1016/j.bmc.2013.09.010
BindingDB Entry DOI: 10.7270/Q2H133G8
More data for this
Ligand-Target Pair
Monocarboxylate transporter 4


(Homo sapiens (Human))
BDBM50442705
PNG
(CHEMBL2442505)
Show SMILES Cc1c(C(O)=O)c(=O)oc2cc(O)ccc12
Show InChI InChI=1S/C11H8O5/c1-5-7-3-2-6(12)4-8(7)16-11(15)9(5)10(13)14/h2-4,12H,1H3,(H,13,14)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Institut de Recherche Exp£rimentale et Clinique (IREC)

Curated by ChEMBL


Assay Description
Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...


Bioorg Med Chem 21: 7107-17 (2013)


Article DOI: 10.1016/j.bmc.2013.09.010
BindingDB Entry DOI: 10.7270/Q2H133G8
More data for this
Ligand-Target Pair