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5 similar compounds to monomer 50446954

Wt: 377.9
BDBM50446952
Wt: 377.9
BDBM50446955
Wt: 343.4
BDBM50446956
Wt: 363.8
BDBM50446957
Wt: 329.4
BDBM50446958

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50446952,50446955,50446956,50446957,50446958   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TG 1019


(HUMAN)
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 454n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in neutrophils assessed as inhibition of 5-oxo-ETE-induced cell migration after 2 hrs ...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair
TG 1019


(HUMAN)
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 33n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin ...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair
TG 1019


(HUMAN)
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 28n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair
TG 1019


(HUMAN)
BDBM50446955
PNG
(CHEMBL3115792)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2ccc(Cl)cc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-17-21(19(24)11-14(2)12-20(25)26)16-10-9-15(22)13-18(16)23(17)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 81n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair
TG 1019


(HUMAN)
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 6n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair
TG 1019


(HUMAN)
BDBM50446957
PNG
(CHEMBL3115790)
Show SMILES CCCCCCc1c(C(=O)CCCC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-8-17-20(18(23)9-7-10-19(24)25)15-13-14(21)11-12-16(15)22(17)2/h11-13H,3-10H2,1-2H3,(H,24,25)
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n/an/a 566n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair
TG 1019


(HUMAN)
BDBM50446958
PNG
(CHEMBL3115789)
Show SMILES CCCCCCc1c(C(=O)CCCC(O)=O)c2ccccc2n1C
Show InChI InChI=1S/C20H27NO3/c1-3-4-5-6-12-17-20(18(22)13-9-14-19(23)24)15-10-7-8-11-16(15)21(17)2/h7-8,10-11H,3-6,9,12-14H2,1-2H3,(H,23,24)
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n/an/a 6.06E+3n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair
TG 1019


(HUMAN)
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 2.73E+3n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair
TG 1019


(HUMAN)
BDBM50446956
PNG
(CHEMBL3115791)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2ccccc2n1C
Show InChI InChI=1S/C21H29NO3/c1-4-5-6-7-12-18-21(19(23)13-15(2)14-20(24)25)16-10-8-9-11-17(16)22(18)3/h8-11,15H,4-7,12-14H2,1-3H3,(H,24,25)
UniProtKB/SwissProt

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PubMed
n/an/a 314n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)

More data for this
Ligand-Target Pair