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17 similar compounds to monomer 50314409

Compile data set for download or QSAR
Wt: 309.3
BDBM50867
Purchase
Wt: 263.3
BDBM50186660
Wt: 365.4
BDBM50314417
Wt: 367.4
BDBM50314419
Wt: 352.4
BDBM50314421
Wt: 341.4
BDBM50314423
Wt: 358.4
BDBM50314424
Wt: 366.4
BDBM50314425
Wt: 379.5
BDBM50314426
Wt: 315.4
BDBM50314410
Wt: 385.5
BDBM50314411
Wt: 420.3
BDBM50314412
Wt: 385.9
BDBM50314413
Wt: 351.4
BDBM50314414
Wt: 395.4
BDBM50314415
Displayed 1 to 15 (of 17 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50867,50186660,50314417,50314419,50314421,50314423,50314424,50314425,50314426,50314410,50314411,50314412,50314413,50314414,50314415   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
BZLF2


(Human herpesvirus 4 type 2)
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 7.15E+3n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2057DCW
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314426
PNG
(3-amino-4-phenethyl-5,6,7,8,9,10-hexahydrocyclooct...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(CCc3ccccc3)c2c1N
Show InChI InChI=1S/C22H25N3OS/c23-19-18-16(13-12-14-8-4-3-5-9-14)15-10-6-1-2-7-11-17(15)25-22(18)27-20(19)21(24)26/h3-5,8-9H,1-2,6-7,10-13,23H2,(H2,24,26)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Phospholipase A2


(Homo sapiens (Human))
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 8.38E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q26M35BC
More data for this
Ligand-Target Pair
Inhibitor of NF-kappa-B kinase (IKK)


(Homo sapiens (Human))
BDBM50186660
PNG
(3-amino-6-butyl-4-methyl-thieno[2,3-b]pyridine-2-c...)
Show SMILES CCCCc1cc(C)c2c(N)c(sc2n1)C(N)=O
Show InChI InChI=1S/C13H17N3OS/c1-3-4-5-8-6-7(2)9-10(14)11(12(15)17)18-13(9)16-8/h6H,3-5,14H2,1-2H3,(H2,15,17)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of IKK beta


J Med Chem 49: 2898-908 (2006)


Article DOI: 10.1021/jm0510979
BindingDB Entry DOI: 10.7270/Q2TQ614S
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314410
PNG
(3-amino-4-cyclopropyl-5,6,7,8,9,10-hexahydrocycloo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(C3CC3)c2c1N
Show InChI InChI=1S/C17H21N3OS/c18-14-13-12(9-7-8-9)10-5-3-1-2-4-6-11(10)20-17(13)22-15(14)16(19)21/h9H,1-8,18H2,(H2,19,21)
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n/an/a 2.00E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314411
PNG
(CHEMBL1093056 | rac-3-amino-4-(6-methylhept-5-en-2...)
Show SMILES CC(CCC=C(C)C)c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C22H31N3OS/c1-13(2)9-8-10-14(3)17-15-11-6-4-5-7-12-16(15)25-22-18(17)19(23)20(27-22)21(24)26/h9,14H,4-8,10-12,23H2,1-3H3,(H2,24,26)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314412
PNG
(3-amino-4-(3,4-dichlorophenyl)-5,6,7,8,9,10-hexahy...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(Cl)c(Cl)c3)c2c1N
Show InChI InChI=1S/C20H19Cl2N3OS/c21-12-8-7-10(9-13(12)22)15-11-5-3-1-2-4-6-14(11)25-20-16(15)17(23)18(27-20)19(24)26/h7-9H,1-6,23H2,(H2,24,26)
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n/an/a 990n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314413
PNG
(3-amino-4-(4-chlorophenyl)-5,6,7,8,9,10-hexahydroc...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(Cl)cc3)c2c1N
Show InChI InChI=1S/C20H20ClN3OS/c21-12-9-7-11(8-10-12)15-13-5-3-1-2-4-6-14(13)24-20-16(15)17(22)18(26-20)19(23)25/h7-10H,1-6,22H2,(H2,23,25)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314414
PNG
(3-amino-4-phenyl-5,6,7,8,9,10-hexahydrocycloocta[b...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C20H21N3OS/c21-17-16-15(12-8-4-3-5-9-12)13-10-6-1-2-7-11-14(13)23-20(16)25-18(17)19(22)24/h3-5,8-9H,1-2,6-7,10-11,21H2,(H2,22,24)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314415
PNG
(4-(3-amino-2-carbamoyl-5,6,7,8,9,10-hexahydrocyclo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(cc3)C(O)=O)c2c1N
Show InChI InChI=1S/C21H21N3O3S/c22-17-16-15(11-7-9-12(10-8-11)21(26)27)13-5-3-1-2-4-6-14(13)24-20(16)28-18(17)19(23)25/h7-10H,1-6,22H2,(H2,23,25)(H,26,27)
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n/an/a 860n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314417
PNG
(3-amino-4-m-tolyl-5,6,7,8,9,10-hexahydrocycloocta[...)
Show SMILES Cc1cccc(c1)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C21H23N3OS/c1-12-7-6-8-13(11-12)16-14-9-4-2-3-5-10-15(14)24-21-17(16)18(22)19(26-21)20(23)25/h6-8,11H,2-5,9-10,22H2,1H3,(H2,23,25)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314419
PNG
((E)-3-amino-4-(2-(furan-2-yl)vinyl)-5,6,7,8,9,10-h...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(\C=C\c3ccco3)c2c1N
Show InChI InChI=1S/C20H21N3O2S/c21-17-16-14(10-9-12-6-5-11-25-12)13-7-3-1-2-4-8-15(13)23-20(16)26-18(17)19(22)24/h5-6,9-11H,1-4,7-8,21H2,(H2,22,24)/b10-9+
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n/an/a 320n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314421
PNG
(3-amino-4-(pyridin-3-yl)-5,6,7,8,9,10-hexahydrocyc...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3cccnc3)c2c1N
Show InChI InChI=1S/C19H20N4OS/c20-16-15-14(11-6-5-9-22-10-11)12-7-3-1-2-4-8-13(12)23-19(15)25-17(16)18(21)24/h5-6,9-10H,1-4,7-8,20H2,(H2,21,24)
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n/an/a 940n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314423
PNG
(3-amino-4-(furan-3-yl)-5,6,7,8,9,10-hexahydrocyclo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccoc3)c2c1N
Show InChI InChI=1S/C18H19N3O2S/c19-15-14-13(10-7-8-23-9-10)11-5-3-1-2-4-6-12(11)21-18(14)24-16(15)17(20)22/h7-9H,1-6,19H2,(H2,20,22)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314424
PNG
(3-amino-4-(thiazol-2-yl)-5,6,7,8,9,10-hexahydrocyc...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3nccs3)c2c1N
Show InChI InChI=1S/C17H18N4OS2/c18-13-12-11(16-20-7-8-23-16)9-5-3-1-2-4-6-10(9)21-17(12)24-14(13)15(19)22/h7-8H,1-6,18H2,(H2,19,22)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314425
PNG
(3-amino-4-(3-methylpyridin-2-yl)-5,6,7,8,9,10-hexa...)
Show SMILES Cc1cccnc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C20H22N4OS/c1-11-7-6-10-23-17(11)14-12-8-4-2-3-5-9-13(12)24-20-15(14)16(21)18(26-20)19(22)25/h6-7,10H,2-5,8-9,21H2,1H3,(H2,22,25)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
cysteine protease ATG4B isoform a


(Homo sapiens (Human))
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 1.23E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2BZ64H1
More data for this
Ligand-Target Pair