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20 similar compounds to monomer 50314421

Compile data set for download or QSAR
Wt: 309.3
BDBM50867
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Wt: 456.5
BDBM51649
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Wt: 343.4
BDBM62990
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Wt: 399.4
BDBM50314416
Wt: 365.4
BDBM50314417
Wt: 341.4
BDBM50314418
Wt: 371.5
BDBM50314420
Wt: 354.4
BDBM50314422
Wt: 341.4
BDBM50314423
Wt: 366.4
BDBM50314425
Wt: 379.5
BDBM50314426
Wt: 331.4
BDBM50314409
Wt: 315.4
BDBM50314410
Wt: 385.5
BDBM50314411
Wt: 420.3
BDBM50314412
Displayed 1 to 15 (of 20 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50867,51649,62990,50314416,50314417,50314418,50314420,50314422,50314423,50314425,50314426,50314409,50314410,50314411,50314412   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
BZLF2


(Human herpesvirus 4 type 2)
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 7.15E+3n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2057DCW
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314426
PNG
(3-amino-4-phenethyl-5,6,7,8,9,10-hexahydrocyclooct...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(CCc3ccccc3)c2c1N
Show InChI InChI=1S/C22H25N3OS/c23-19-18-16(13-12-14-8-4-3-5-9-14)15-10-6-1-2-7-11-17(15)25-22(18)27-20(19)21(24)26/h3-5,8-9H,1-2,6-7,10-13,23H2,(H2,24,26)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM62990
PNG
(3-Amino-4-thiophen-2-yl-6,7,8,9-tetrahydro-5H-1-th...)
Show SMILES NC(=O)c1sc2nc3CCCCCc3c(-c3cccs3)c2c1N
Show InChI InChI=1S/C17H17N3OS2/c18-14-13-12(11-7-4-8-22-11)9-5-2-1-3-6-10(9)20-17(13)23-15(14)16(19)21/h4,7-8H,1-3,5-6,18H2,(H2,19,21)
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n/an/an/an/a 285n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2MW2FKX
More data for this
Ligand-Target Pair
cysteine protease ATG4B isoform a


(Homo sapiens (Human))
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 1.23E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2BZ64H1
More data for this
Ligand-Target Pair
Phospholipase A2


(Homo sapiens (Human))
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 8.38E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q26M35BC
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314409
PNG
(3-amino-4-isobutyl-5,6,7,8,9,10-hexahydrocycloocta...)
Show SMILES CC(C)Cc1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C18H25N3OS/c1-10(2)9-12-11-7-5-3-4-6-8-13(11)21-18-14(12)15(19)16(23-18)17(20)22/h10H,3-9,19H2,1-2H3,(H2,20,22)
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n/an/a 860n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314410
PNG
(3-amino-4-cyclopropyl-5,6,7,8,9,10-hexahydrocycloo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(C3CC3)c2c1N
Show InChI InChI=1S/C17H21N3OS/c18-14-13-12(9-7-8-9)10-5-3-1-2-4-6-11(10)20-17(13)22-15(14)16(19)21/h9H,1-8,18H2,(H2,19,21)
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n/an/a 2.00E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314411
PNG
(CHEMBL1093056 | rac-3-amino-4-(6-methylhept-5-en-2...)
Show SMILES CC(CCC=C(C)C)c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C22H31N3OS/c1-13(2)9-8-10-14(3)17-15-11-6-4-5-7-12-16(15)25-22-18(17)19(23)20(27-22)21(24)26/h9,14H,4-8,10-12,23H2,1-3H3,(H2,24,26)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314412
PNG
(3-amino-4-(3,4-dichlorophenyl)-5,6,7,8,9,10-hexahy...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(Cl)c(Cl)c3)c2c1N
Show InChI InChI=1S/C20H19Cl2N3OS/c21-12-8-7-10(9-13(12)22)15-11-5-3-1-2-4-6-14(11)25-20-16(15)17(23)18(27-20)19(24)26/h7-9H,1-6,23H2,(H2,24,26)
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n/an/a 990n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314416
PNG
(3-amino-4-(2-fluoro-5-methoxyphenyl)-5,6,7,8,9,10-...)
Show SMILES COc1ccc(F)c(c1)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C21H22FN3O2S/c1-27-11-8-9-14(22)13(10-11)16-12-6-4-2-3-5-7-15(12)25-21-17(16)18(23)19(28-21)20(24)26/h8-10H,2-7,23H2,1H3,(H2,24,26)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314417
PNG
(3-amino-4-m-tolyl-5,6,7,8,9,10-hexahydrocycloocta[...)
Show SMILES Cc1cccc(c1)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C21H23N3OS/c1-12-7-6-8-13(11-12)16-14-9-4-2-3-5-10-15(14)24-21-17(16)18(22)19(26-21)20(23)25/h6-8,11H,2-5,9-10,22H2,1H3,(H2,23,25)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314418
PNG
(3-amino-4-(furan-2-yl)-5,6,7,8,9,10-hexahydrocyclo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C18H19N3O2S/c19-15-14-13(12-8-5-9-23-12)10-6-3-1-2-4-7-11(10)21-18(14)24-16(15)17(20)22/h5,8-9H,1-4,6-7,19H2,(H2,20,22)
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n/an/a 640n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314420
PNG
(3-amino-4-(3-methylthiophen-2-yl)-5,6,7,8,9,10-hex...)
Show SMILES Cc1ccsc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C19H21N3OS2/c1-10-8-9-24-16(10)13-11-6-4-2-3-5-7-12(11)22-19-14(13)15(20)17(25-19)18(21)23/h8-9H,2-7,20H2,1H3,(H2,21,23)
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n/an/a 460n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314422
PNG
(3-amino-4-(1-methyl-1H-pyrrol-2-yl)-5,6,7,8,9,10-h...)
Show SMILES Cn1cccc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C19H22N4OS/c1-23-10-6-9-13(23)14-11-7-4-2-3-5-8-12(11)22-19-15(14)16(20)17(25-19)18(21)24/h6,9-10H,2-5,7-8,20H2,1H3,(H2,21,24)
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n/an/a 990n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314423
PNG
(3-amino-4-(furan-3-yl)-5,6,7,8,9,10-hexahydrocyclo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccoc3)c2c1N
Show InChI InChI=1S/C18H19N3O2S/c19-15-14-13(10-7-8-23-9-10)11-5-3-1-2-4-6-12(11)21-18(14)24-16(15)17(20)22/h7-9H,1-6,19H2,(H2,20,22)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314425
PNG
(3-amino-4-(3-methylpyridin-2-yl)-5,6,7,8,9,10-hexa...)
Show SMILES Cc1cccnc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C20H22N4OS/c1-11-7-6-10-23-17(11)14-12-8-4-2-3-5-9-13(12)24-20-15(14)16(21)18(26-20)19(22)25/h6-7,10H,2-5,8-9,21H2,1H3,(H2,22,25)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
dTDP-4-dehydrorhamnose 3,5-epimerase RmlC


(Mycobacterium tuberculosis H37Rv)
BDBM51649
PNG
(MLS000530131 | SMR000127103 | cid_1283398)
Show SMILES CC(=O)Nc1ccc(NC(=O)c2sc3nc4CCCc4c(-c4ccc(C)cc4)c3c2N)cc1
Show InChI InChI=1S/C26H24N4O2S/c1-14-6-8-16(9-7-14)21-19-4-3-5-20(19)30-26-22(21)23(27)24(33-26)25(32)29-18-12-10-17(11-13-18)28-15(2)31/h6-13H,3-5,27H2,1-2H3,(H,28,31)(H,29,32)
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n/an/a 6.95E+3n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Michael McNeil, Colorado State Universi...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2TD9VRT
More data for this
Ligand-Target Pair