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22 similar compounds to monomer 50314408

Compile data set for download or QSAR
Wt: 339.4
BDBM5925
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Wt: 309.3
BDBM50867
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Wt: 343.4
BDBM62990
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Wt: 263.3
BDBM50186660
Wt: 263.3
BDBM50186652
Wt: 365.4
BDBM50314417
Wt: 367.4
BDBM50314419
Wt: 371.5
BDBM50314420
Wt: 352.4
BDBM50314421
Wt: 354.4
BDBM50314422
Wt: 341.4
BDBM50314423
Wt: 358.4
BDBM50314424
Wt: 366.4
BDBM50314425
Wt: 379.5
BDBM50314426
Wt: 331.4
BDBM50314409
Displayed 1 to 15 (of 22 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 5925,50867,62990,50186660,50186652,50314417,50314419,50314420,50314421,50314422,50314423,50314424,50314425,50314426,50314409   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
BZLF2


(Human herpesvirus 4 type 2)
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 7.15E+3n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2057DCW
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314426
PNG
(3-amino-4-phenethyl-5,6,7,8,9,10-hexahydrocyclooct...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(CCc3ccccc3)c2c1N
Show InChI InChI=1S/C22H25N3OS/c23-19-18-16(13-12-14-8-4-3-5-9-14)15-10-6-1-2-7-11-17(15)25-22(18)27-20(19)21(24)26/h3-5,8-9H,1-2,6-7,10-13,23H2,(H2,24,26)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
cysteine protease ATG4B isoform a


(Homo sapiens (Human))
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 1.23E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2BZ64H1
More data for this
Ligand-Target Pair
Phospholipase A2


(Homo sapiens (Human))
BDBM50867
PNG
(3-amino-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thien...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccccc3)c2c1N
Show InChI InChI=1S/C17H15N3OS/c18-14-13-12(9-5-2-1-3-6-9)10-7-4-8-11(10)20-17(13)22-15(14)16(19)21/h1-3,5-6H,4,7-8,18H2,(H2,19,21)
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n/an/a 8.38E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q26M35BC
More data for this
Ligand-Target Pair
nuclear receptor coactivator 3 isoform a


(Homo sapiens (Human))
BDBM5925
PNG
(cid_699688)
Show SMILES Cc1nc2sc(C(N)=O)c(N)c2c(C)c1CC(=O)c1ccccc1
Show InChI InChI=1S/C18H17N3O2S/c1-9-12(8-13(22)11-6-4-3-5-7-11)10(2)21-18-14(9)15(19)16(24-18)17(20)23/h3-7H,8,19H2,1-2H3,(H2,20,23)
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n/an/a 2.63E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2C24V0K
More data for this
Ligand-Target Pair
Nuclear receptor coactivator 1


(Homo sapiens (Human))
BDBM5925
PNG
(cid_699688)
Show SMILES Cc1nc2sc(C(N)=O)c(N)c2c(C)c1CC(=O)c1ccccc1
Show InChI InChI=1S/C18H17N3O2S/c1-9-12(8-13(22)11-6-4-3-5-7-11)10(2)21-18-14(9)15(19)16(24-18)17(20)23/h3-7H,8,19H2,1-2H3,(H2,20,23)
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n/an/a>3.99E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2794387
More data for this
Ligand-Target Pair
Inhibitor of NF-kappa-B kinase (IKK)


(Homo sapiens (Human))
BDBM50186652
PNG
(3-amino-6-isobutyl-4-methyl-thieno[2,3-b]pyridine-...)
Show SMILES CC(C)Cc1cc(C)c2c(N)c(sc2n1)C(N)=O
Show InChI InChI=1S/C13H17N3OS/c1-6(2)4-8-5-7(3)9-10(14)11(12(15)17)18-13(9)16-8/h5-6H,4,14H2,1-3H3,(H2,15,17)
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n/an/a 4.10E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of IKK beta


J Med Chem 49: 2898-908 (2006)


Article DOI: 10.1021/jm0510979
BindingDB Entry DOI: 10.7270/Q2TQ614S
More data for this
Ligand-Target Pair
Inhibitor of NF-kappa-B kinase (IKK)


(Homo sapiens (Human))
BDBM50186660
PNG
(3-amino-6-butyl-4-methyl-thieno[2,3-b]pyridine-2-c...)
Show SMILES CCCCc1cc(C)c2c(N)c(sc2n1)C(N)=O
Show InChI InChI=1S/C13H17N3OS/c1-3-4-5-8-6-7(2)9-10(14)11(12(15)17)18-13(9)16-8/h6H,3-5,14H2,1-2H3,(H2,15,17)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of IKK beta


J Med Chem 49: 2898-908 (2006)


Article DOI: 10.1021/jm0510979
BindingDB Entry DOI: 10.7270/Q2TQ614S
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314409
PNG
(3-amino-4-isobutyl-5,6,7,8,9,10-hexahydrocycloocta...)
Show SMILES CC(C)Cc1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C18H25N3OS/c1-10(2)9-12-11-7-5-3-4-6-8-13(11)21-18-14(12)15(19)16(23-18)17(20)22/h10H,3-9,19H2,1-2H3,(H2,20,22)
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n/an/a 860n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314417
PNG
(3-amino-4-m-tolyl-5,6,7,8,9,10-hexahydrocycloocta[...)
Show SMILES Cc1cccc(c1)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C21H23N3OS/c1-12-7-6-8-13(11-12)16-14-9-4-2-3-5-10-15(14)24-21-17(16)18(22)19(26-21)20(23)25/h6-8,11H,2-5,9-10,22H2,1H3,(H2,23,25)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314419
PNG
((E)-3-amino-4-(2-(furan-2-yl)vinyl)-5,6,7,8,9,10-h...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(\C=C\c3ccco3)c2c1N
Show InChI InChI=1S/C20H21N3O2S/c21-17-16-14(10-9-12-6-5-11-25-12)13-7-3-1-2-4-8-15(13)23-20(16)26-18(17)19(22)24/h5-6,9-11H,1-4,7-8,21H2,(H2,22,24)/b10-9+
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n/an/a 320n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314420
PNG
(3-amino-4-(3-methylthiophen-2-yl)-5,6,7,8,9,10-hex...)
Show SMILES Cc1ccsc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C19H21N3OS2/c1-10-8-9-24-16(10)13-11-6-4-2-3-5-7-12(11)22-19-14(13)15(20)17(25-19)18(21)23/h8-9H,2-7,20H2,1H3,(H2,21,23)
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n/an/a 460n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314421
PNG
(3-amino-4-(pyridin-3-yl)-5,6,7,8,9,10-hexahydrocyc...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3cccnc3)c2c1N
Show InChI InChI=1S/C19H20N4OS/c20-16-15-14(11-6-5-9-22-10-11)12-7-3-1-2-4-8-13(12)23-19(15)25-17(16)18(21)24/h5-6,9-10H,1-4,7-8,20H2,(H2,21,24)
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n/an/a 940n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314422
PNG
(3-amino-4-(1-methyl-1H-pyrrol-2-yl)-5,6,7,8,9,10-h...)
Show SMILES Cn1cccc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C19H22N4OS/c1-23-10-6-9-13(23)14-11-7-4-2-3-5-8-12(11)22-19-15(14)16(20)17(25-19)18(21)24/h6,9-10H,2-5,7-8,20H2,1H3,(H2,21,24)
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n/an/a 990n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314423
PNG
(3-amino-4-(furan-3-yl)-5,6,7,8,9,10-hexahydrocyclo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccoc3)c2c1N
Show InChI InChI=1S/C18H19N3O2S/c19-15-14-13(10-7-8-23-9-10)11-5-3-1-2-4-6-12(11)21-18(14)24-16(15)17(20)22/h7-9H,1-6,19H2,(H2,20,22)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314424
PNG
(3-amino-4-(thiazol-2-yl)-5,6,7,8,9,10-hexahydrocyc...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3nccs3)c2c1N
Show InChI InChI=1S/C17H18N4OS2/c18-13-12-11(16-20-7-8-23-16)9-5-3-1-2-4-6-10(9)21-17(12)24-14(13)15(19)22/h7-8H,1-6,18H2,(H2,19,22)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314425
PNG
(3-amino-4-(3-methylpyridin-2-yl)-5,6,7,8,9,10-hexa...)
Show SMILES Cc1cccnc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C20H22N4OS/c1-11-7-6-10-23-17(11)14-12-8-4-2-3-5-9-13(12)24-20-15(14)16(21)18(26-20)19(22)25/h6-7,10H,2-5,8-9,21H2,1H3,(H2,22,25)
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n/an/a>2.00E+4n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM62990
PNG
(3-Amino-4-thiophen-2-yl-6,7,8,9-tetrahydro-5H-1-th...)
Show SMILES NC(=O)c1sc2nc3CCCCCc3c(-c3cccs3)c2c1N
Show InChI InChI=1S/C17H17N3OS2/c18-14-13-12(11-7-4-8-22-11)9-5-2-1-3-6-10(9)20-17(13)23-15(14)16(19)21/h4,7-8H,1-3,5-6,18H2,(H2,19,21)
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n/an/an/an/a 285n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2MW2FKX
More data for this
Ligand-Target Pair