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1 similar compounds to monomer 60589

Compile data set for download or QSAR
Wt: 760.8
BDBM60625

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60625   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gag-Pol polyprotein


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM60625
PNG
(US9133157, 106)
Show SMILES COC(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)N[C@H](c1ccc(s1)[C@@H](CO)N(C(C)C)S(=O)(=O)c1ccc2ncsc2c1)C(F)(F)F
Show InChI InChI=1/C35H35F3N4O6S3/c1-21(2)42(51(46,47)24-14-15-25-29(18-24)49-20-39-25)26(19-43)27-16-17-28(50-27)32(35(36,37)38)41-33(44)31(40-34(45)48-3)30(22-10-6-4-7-11-22)23-12-8-5-9-13-23/h4-18,20-21,26,30-32,43H,19H2,1-3H3,(H,40,45)(H,41,44)/t26-,31+,32-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 34.7n/an/an/an/a5.525



Merck Canada Inc.

US Patent


Assay Description
The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...


US Patent US9133157 (2015)


BindingDB Entry DOI: 10.7270/Q2Q52NDV
More data for this
Ligand-Target Pair