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2 similar compounds to monomer 25321

Wt: 432.4
BDBM66198
Wt: 444.4
BDBM73094

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 66198,73094   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
nuclear receptor corepressor 2 isoform 2


(Homo sapiens)
BDBM66198
PNG
((4Z)-4-[1,3-benzodioxol-5-yl(hydroxy)methylene]-5-...)
Show SMILES Fc1cccc(c1)C1C(C(=O)c2ccc3OCOc3c2)C(=O)C(=O)N1Cc1cccnc1
Show InChI InChI=1S/C24H17FN2O5/c25-17-5-1-4-15(9-17)21-20(22(28)16-6-7-18-19(10-16)32-13-31-18)23(29)24(30)27(21)12-14-3-2-8-26-11-14/h1-11,20-21H,12-13H2
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a 4.89E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...


PubChem Bioassay (2010)

More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM73094
PNG
((4E)-4-[2,3-dihydro-1,4-benzodioxin-6-yl(hydroxy)m...)
Show SMILES Oc1cccc(c1)C1C(C(=O)c2ccc3OCCOc3c2)C(=O)C(=O)N1Cc1cccnc1
Show InChI InChI=1S/C25H20N2O6/c28-18-5-1-4-16(11-18)22-21(23(29)17-6-7-19-20(12-17)33-10-9-32-19)24(30)25(31)27(22)14-15-3-2-8-26-13-15/h1-8,11-13,21-22,28H,9-10,14H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a>2.60E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)

More data for this
Ligand-Target Pair
photoreceptor-specific nuclear receptor


(Homo sapiens)
BDBM66198
PNG
((4Z)-4-[1,3-benzodioxol-5-yl(hydroxy)methylene]-5-...)
Show SMILES Fc1cccc(c1)C1C(C(=O)c2ccc3OCOc3c2)C(=O)C(=O)N1Cc1cccnc1
Show InChI InChI=1S/C24H17FN2O5/c25-17-5-1-4-15(9-17)21-20(22(28)16-6-7-18-19(10-16)32-13-31-18)23(29)24(30)27(21)12-14-3-2-8-26-11-14/h1-11,20-21H,12-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a>3.98E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...


PubChem Bioassay (2010)

More data for this
Ligand-Target Pair