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2 similar compounds to monomer 50080537

Compile data set for download or QSAR
Wt: 257.2
BDBM66279
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Wt: 285.3
BDBM50303528

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 66279,50303528   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303528
PNG
(CHEMBL576920 | [1-(2-Hydroxyethyl)-1H-indol-3-yl](...)
Show SMILES CC1(C)C(C(=O)c2cn(CCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C18H23NO2/c1-17(2)16(18(17,3)4)15(21)13-11-19(9-10-20)14-8-6-5-7-12(13)14/h5-8,11,16,20H,9-10H2,1-4H3
PDB

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PC cid
PC sid
UniChem

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Article
PubMed
56n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303528
PNG
(CHEMBL576920 | [1-(2-Hydroxyethyl)-1H-indol-3-yl](...)
Show SMILES CC1(C)C(C(=O)c2cn(CCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C18H23NO2/c1-17(2)16(18(17,3)4)15(21)13-11-19(9-10-20)14-8-6-5-7-12(13)14/h5-8,11,16,20H,9-10H2,1-4H3
PDB

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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens (Human))
BDBM66279
PNG
(2-[3-(cyclopropanecarbonyl)indol-1-yl]acetic acid ...)
Show SMILES COC(=O)Cn1cc(C(=O)C2CC2)c2ccccc12
Show InChI InChI=1S/C15H15NO3/c1-19-14(17)9-16-8-12(15(18)10-6-7-10)11-4-2-3-5-13(11)16/h2-5,8,10H,6-7,9H2,1H3
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PCBioAssay
n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303528
PNG
(CHEMBL576920 | [1-(2-Hydroxyethyl)-1H-indol-3-yl](...)
Show SMILES CC1(C)C(C(=O)c2cn(CCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C18H23NO2/c1-17(2)16(18(17,3)4)15(21)13-11-19(9-10-20)14-8-6-5-7-12(13)14/h5-8,11,16,20H,9-10H2,1-4H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 440n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair