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36 similar compounds to monomer 50188385

Compile data set for download or QSAR
Wt: 368.5
BDBM150278
Wt: 366.4
BDBM150279
Wt: 380.5
BDBM150280
Wt: 370.4
BDBM150281
Wt: 366.4
BDBM150282
Wt: 352.4
BDBM150283
Wt: 352.4
BDBM150284
Wt: 366.4
BDBM150275
Purchase
Wt: 340.4
BDBM150276
Wt: 354.4
BDBM150277
Wt: 484.7
BDBM66646
Purchase
Wt: 428.6
BDBM70293
Purchase
Wt: 386.5
BDBM86680
Wt: 302.4
BDBM91714
Wt: 318.4
BDBM91717
Displayed 1 to 15 (of 36 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 150278,150279,150280,150281,150282,150283,150284,150275,150276,150277,66646,70293,86680,91714,91717   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM86680
PNG
(CAS_4042 | Mpa | NSC_4042)
Show SMILES CC1CC2C3CCC(OC(C)=O)(C(C)=O)C3(C)CCC2C2(C)CCC(=O)C=C12
Show InChI InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3
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PubMed
13n/an/an/an/an/an/an/an/a



Meiji Seika Kaisha, Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 313: 916-20 (2005)


Article DOI: 10.1124/jpet.104.074146
BindingDB Entry DOI: 10.7270/Q24T6GZR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM86680
PNG
(CAS_4042 | Mpa | NSC_4042)
Show SMILES CC1CC2C3CCC(OC(C)=O)(C(C)=O)C3(C)CCC2C2(C)CCC(=O)C=C12
Show InChI InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3
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19n/an/an/an/an/an/an/an/a



Meiji Seika Kaisha, Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 313: 916-20 (2005)


Article DOI: 10.1124/jpet.104.074146
BindingDB Entry DOI: 10.7270/Q24T6GZR
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM86680
PNG
(CAS_4042 | Mpa | NSC_4042)
Show SMILES CC1CC2C3CCC(OC(C)=O)(C(C)=O)C3(C)CCC2C2(C)CCC(=O)C=C12
Show InChI InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3
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43n/an/an/an/an/an/an/an/a



Meiji Seika Kaisha, Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 313: 916-20 (2005)


Article DOI: 10.1124/jpet.104.074146
BindingDB Entry DOI: 10.7270/Q24T6GZR
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM86680
PNG
(CAS_4042 | Mpa | NSC_4042)
Show SMILES CC1CC2C3CCC(OC(C)=O)(C(C)=O)C3(C)CCC2C2(C)CCC(=O)C=C12
Show InChI InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Meiji Seika Kaisha, Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 313: 916-20 (2005)


Article DOI: 10.1124/jpet.104.074146
BindingDB Entry DOI: 10.7270/Q24T6GZR
More data for this
Ligand-Target Pair
Cholinesterase


(Homo sapiens (Human))
BDBM91717
PNG
(11alpha-Hydroxytestolactone, 6)
Show SMILES C[C@]12C[C@@H](O)C3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CCC(=O)O2
Show InChI InChI=1S/C19H26O4/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)23-19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15+,17?,18-,19-/m0/s1
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n/an/a 2.84E+5n/an/an/an/an/an/a



University of Jordan



Assay Description
AChE and BChE inhibiting activities were measured in vitro by a modified spectrophotometric method previously developed by Ellman et. al.


J Enzyme Inhib Med Chem 24: 553-8 (2009)


Article DOI: 10.1080/14756360802236393
BindingDB Entry DOI: 10.7270/Q20K274X
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150275
PNG
(US8987239, A | US9034856, A)
Show SMILES C[C@]12CC[C@H]3[C@@H]([C@H]4C[C@H]4C4=CC(=O)CC[C@]34C)[C@@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
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n/an/a 43.3n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150276
PNG
(US8987239, 1)
Show SMILES C[C@]12CCC3C(CCC4=CC(=O)CCC34)C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C22H28O3/c1-21-8-6-15-14-5-3-13(23)10-12(14)2-4-16(15)20(21)17-11-18(17)22(21)9-7-19(24)25-22/h10,14-18,20H,2-9,11H2,1H3/t14?,15?,16?,17?,18?,20?,21-,22-/m0/s1
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n/an/a 15n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150277
PNG
(US8987239, 3)
Show SMILES CC1CC2=CC(=O)CCC2C2CC[C@@]3(C)C(C4CC4[C@@]33CCC(=O)O3)C12
Show InChI InChI=1S/C23H30O3/c1-12-9-13-10-14(24)3-4-15(13)16-5-7-22(2)21(20(12)16)17-11-18(17)23(22)8-6-19(25)26-23/h10,12,15-18,20-21H,3-9,11H2,1-2H3/t12?,15?,16?,17?,18?,20?,21?,22-,23-/m0/s1
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n/an/a 12.1n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150278
PNG
(US8987239, 4)
Show SMILES CCC1CC2=CC(=O)CCC2C2CC[C@@]3(C)C(C4CC4[C@@]33CCC(=O)O3)C12
Show InChI InChI=1S/C24H32O3/c1-3-13-10-14-11-15(25)4-5-16(14)17-6-8-23(2)22(21(13)17)18-12-19(18)24(23)9-7-20(26)27-24/h11,13,16-19,21-22H,3-10,12H2,1-2H3/t13?,16?,17?,18?,19?,21?,22?,23-,24-/m0/s1
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n/an/a 33n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150279
PNG
(US8987239, 5)
Show SMILES C[C@]12CCC3C4CCC(=O)C=C4CC(C=C)C3C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-3-13-10-14-11-15(25)4-5-16(14)17-6-8-23(2)22(21(13)17)18-12-19(18)24(23)9-7-20(26)27-24/h3,11,13,16-19,21-22H,1,4-10,12H2,2H3/t13?,16?,17?,18?,19?,21?,22?,23-,24-/m0/s1
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n/an/a 15n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150280
PNG
(US8987239, 6)
Show SMILES C[C@]12CCC3C4CCC(=O)C=C4CC(C4CC4)C3C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C25H32O3/c1-24-8-6-17-16-5-4-15(26)10-14(16)11-18(13-2-3-13)22(17)23(24)19-12-20(19)25(24)9-7-21(27)28-25/h10,13,16-20,22-23H,2-9,11-12H2,1H3/t16?,17?,18?,19?,20?,22?,23?,24-,25-/m0/s1
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n/an/a 51n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150281
PNG
(US8987239, 7)
Show SMILES C[C@]12CCC3C(C[C@@H](CO)C4=CC(=O)CCC34)C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C23H30O4/c1-22-6-4-15-14-3-2-13(25)9-16(14)12(11-24)8-17(15)21(22)18-10-19(18)23(22)7-5-20(26)27-23/h9,12,14-15,17-19,21,24H,2-8,10-11H2,1H3/t12-,14?,15?,17?,18?,19?,21?,22-,23-/m0/s1
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n/an/a 1.10E+3n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150282
PNG
(US8987239, 8)
Show SMILES C[C@]12CCC3C(CC4(CC4)C4=CC(=O)CCC34)C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-22-6-4-14-15-3-2-13(25)10-18(15)23(8-9-23)12-17(14)21(22)16-11-19(16)24(22)7-5-20(26)27-24/h10,14-17,19,21H,2-9,11-12H2,1H3/t14?,15?,16?,17?,19?,21?,22-,24-/m0/s1
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n/an/a 8.90n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150283
PNG
(US8987239, 9)
Show SMILES C[C@]12CCC3C4CCC(=O)C=C4[C@@H]4C[C@@H]4C3C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C23H28O3/c1-22-6-4-13-12-3-2-11(24)8-14(12)15-9-16(15)20(13)21(22)17-10-18(17)23(22)7-5-19(25)26-23/h8,12-13,15-18,20-21H,2-7,9-10H2,1H3/t12?,13?,15-,16-,17?,18?,20?,21?,22-,23-/m0/s1
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n/an/a 16n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150284
PNG
(US8987239, 9)
Show SMILES C[C@]12CCC3C4CCC(=O)C=C4C4CC4C3C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C23H28O3/c1-22-6-4-13-12-3-2-11(24)8-14(12)15-9-16(15)20(13)21(22)17-10-18(17)23(22)7-5-19(25)26-23/h8,12-13,15-18,20-21H,2-7,9-10H2,1H3/t12?,13?,15?,16?,17?,18?,20?,21?,22-,23-/m0/s1
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n/an/a 24n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150275
PNG
(US8987239, A | US9034856, A)
Show SMILES C[C@]12CC[C@H]3[C@@H]([C@H]4C[C@H]4C4=CC(=O)CC[C@]34C)[C@@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
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n/an/a 630n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150276
PNG
(US8987239, 1)
Show SMILES C[C@]12CCC3C(CCC4=CC(=O)CCC34)C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C22H28O3/c1-21-8-6-15-14-5-3-13(23)10-12(14)2-4-16(15)20(21)17-11-18(17)22(21)9-7-19(24)25-22/h10,14-18,20H,2-9,11H2,1H3/t14?,15?,16?,17?,18?,20?,21-,22-/m0/s1
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n/an/a 6n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150277
PNG
(US8987239, 3)
Show SMILES CC1CC2=CC(=O)CCC2C2CC[C@@]3(C)C(C4CC4[C@@]33CCC(=O)O3)C12
Show InChI InChI=1S/C23H30O3/c1-12-9-13-10-14(24)3-4-15(13)16-5-7-22(2)21(20(12)16)17-11-18(17)23(22)8-6-19(25)26-23/h10,12,15-18,20-21H,3-9,11H2,1-2H3/t12?,15?,16?,17?,18?,20?,21?,22-,23-/m0/s1
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n/an/a 61n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150278
PNG
(US8987239, 4)
Show SMILES CCC1CC2=CC(=O)CCC2C2CC[C@@]3(C)C(C4CC4[C@@]33CCC(=O)O3)C12
Show InChI InChI=1S/C24H32O3/c1-3-13-10-14-11-15(25)4-5-16(14)17-6-8-23(2)22(21(13)17)18-12-19(18)24(23)9-7-20(26)27-24/h11,13,16-19,21-22H,3-10,12H2,1-2H3/t13?,16?,17?,18?,19?,21?,22?,23-,24-/m0/s1
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n/an/a 74n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150279
PNG
(US8987239, 5)
Show SMILES C[C@]12CCC3C4CCC(=O)C=C4CC(C=C)C3C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-3-13-10-14-11-15(25)4-5-16(14)17-6-8-23(2)22(21(13)17)18-12-19(18)24(23)9-7-20(26)27-24/h3,11,13,16-19,21-22H,1,4-10,12H2,2H3/t13?,16?,17?,18?,19?,21?,22?,23-,24-/m0/s1
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n/an/a 55n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150280
PNG
(US8987239, 6)
Show SMILES C[C@]12CCC3C4CCC(=O)C=C4CC(C4CC4)C3C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C25H32O3/c1-24-8-6-17-16-5-4-15(26)10-14(16)11-18(13-2-3-13)22(17)23(24)19-12-20(19)25(24)9-7-21(27)28-25/h10,13,16-20,22-23H,2-9,11-12H2,1H3/t16?,17?,18?,19?,20?,22?,23?,24-,25-/m0/s1
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n/an/a 78n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150281
PNG
(US8987239, 7)
Show SMILES C[C@]12CCC3C(C[C@@H](CO)C4=CC(=O)CCC34)C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C23H30O4/c1-22-6-4-15-14-3-2-13(25)9-16(14)12(11-24)8-17(15)21(22)18-10-19(18)23(22)7-5-20(26)27-23/h9,12,14-15,17-19,21,24H,2-8,10-11H2,1H3/t12-,14?,15?,17?,18?,19?,21?,22-,23-/m0/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150282
PNG
(US8987239, 8)
Show SMILES C[C@]12CCC3C(CC4(CC4)C4=CC(=O)CCC34)C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-22-6-4-14-15-3-2-13(25)10-18(15)23(8-9-23)12-17(14)21(22)16-11-19(16)24(22)7-5-20(26)27-24/h10,14-17,19,21H,2-9,11-12H2,1H3/t14?,15?,16?,17?,19?,21?,22-,24-/m0/s1
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n/an/a 26n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150283
PNG
(US8987239, 9)
Show SMILES C[C@]12CCC3C4CCC(=O)C=C4[C@@H]4C[C@@H]4C3C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C23H28O3/c1-22-6-4-13-12-3-2-11(24)8-14(12)15-9-16(15)20(13)21(22)17-10-18(17)23(22)7-5-19(25)26-23/h8,12-13,15-18,20-21H,2-7,9-10H2,1H3/t12?,13?,15-,16-,17?,18?,20?,21?,22-,23-/m0/s1
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n/an/a 420n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150284
PNG
(US8987239, 9)
Show SMILES C[C@]12CCC3C4CCC(=O)C=C4C4CC4C3C1C1CC1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C23H28O3/c1-22-6-4-13-12-3-2-11(24)8-14(12)15-9-16(15)20(13)21(22)17-10-18(17)23(22)7-5-19(25)26-23/h8,12-13,15-18,20-21H,2-7,9-10H2,1H3/t12?,13?,15?,16?,17?,18?,20?,21?,22-,23-/m0/s1
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n/an/a 330n/an/an/an/an/an/a



Bayer Intellectual Property GbmH

US Patent


Assay Description
The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...


US Patent US8987239 (2015)


BindingDB Entry DOI: 10.7270/Q23N224G
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM150275
PNG
(US8987239, A | US9034856, A)
Show SMILES C[C@]12CC[C@H]3[C@@H]([C@H]4C[C@H]4C4=CC(=O)CC[C@]34C)[C@@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
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n/an/a 43.3n/an/an/an/an/an/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US9034856 (2015)


BindingDB Entry DOI: 10.7270/Q2MP5218
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150275
PNG
(US8987239, A | US9034856, A)
Show SMILES C[C@]12CC[C@H]3[C@@H]([C@H]4C[C@H]4C4=CC(=O)CC[C@]34C)[C@@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
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n/an/a 630n/an/an/an/an/an/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US9034856 (2015)


BindingDB Entry DOI: 10.7270/Q2MP5218
More data for this
Ligand-Target Pair
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM150275
PNG
(US8987239, A | US9034856, A)
Show SMILES C[C@]12CC[C@H]3[C@@H]([C@H]4C[C@H]4C4=CC(=O)CC[C@]34C)[C@@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
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n/an/a 3.30n/an/an/an/an/an/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US9034856 (2015)


BindingDB Entry DOI: 10.7270/Q2MP5218
More data for this
Ligand-Target Pair
Cholinesterase


(Homo sapiens (Human))
BDBM91714
PNG
(Testolactone, 3)
Show SMILES C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CCC(=O)O2
Show InChI InChI=1S/C19H26O3/c1-18-9-7-13(20)11-12(18)3-4-14-15(18)8-10-19(2)16(14)5-6-17(21)22-19/h11,14-16H,3-10H2,1-2H3/t14-,15+,16+,18+,19+/m1/s1
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Article
PubMed
n/an/a 1.42E+5n/an/an/an/an/an/a



University of Jordan



Assay Description
AChE and BChE inhibiting activities were measured in vitro by a modified spectrophotometric method previously developed by Ellman et. al.


J Enzyme Inhib Med Chem 24: 553-8 (2009)


Article DOI: 10.1080/14756360802236393
BindingDB Entry DOI: 10.7270/Q20K274X
More data for this
Ligand-Target Pair
DNA recombination protein RecA


(Mycobacterium tuberculosis H37Rv)
BDBM70293
PNG
(17-alpha-hydroxy-progesterone caproate | HYDROXYPR...)
Show SMILES CCCCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)=O
Show InChI InChI=1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1
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n/an/an/an/a 4.88E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2DR2SX9
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM150275
PNG
(US8987239, A | US9034856, A)
Show SMILES C[C@]12CC[C@H]3[C@@H]([C@H]4C[C@H]4C4=CC(=O)CC[C@]34C)[C@@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1
Show InChI InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
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n/an/a 27n/an/an/an/an/an/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...


US Patent US9034856 (2015)


BindingDB Entry DOI: 10.7270/Q2MP5218
More data for this
Ligand-Target Pair
DNA recombination protein RecA


(Mycobacterium tuberculosis H37Rv)
BDBM70293
PNG
(17-alpha-hydroxy-progesterone caproate | HYDROXYPR...)
Show SMILES CCCCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)=O
Show InChI InChI=1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1
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n/an/an/an/a>3.80E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2FN14NR
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens (Human))
BDBM66646
PNG
((2S,4aS,6aR,6bR,8aR,10S,12aS,14bS)-10-hydroxy-13-k...)
Show SMILES COC(=O)[C@@]1(C)CC[C@]2(C)CC[C@@]3(C)C(=CC(=O)C4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@H]2C1
Show InChI InChI=1S/C31H48O4/c1-26(2)22-9-12-31(7)24(29(22,5)11-10-23(26)33)21(32)17-19-20-18-28(4,25(34)35-8)14-13-27(20,3)15-16-30(19,31)6/h17,20,22-24,33H,9-16,18H2,1-8H3/t20-,22+,23+,24?,27-,28+,29+,30+,31-/m1/s1
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n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair