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4 similar compounds to monomer 50261812

Compile data set for download or QSAR
Wt: 318.3
BDBM69655
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Wt: 198.2
BDBM50186329
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Wt: 274.3
BDBM50261811
Wt: 289.3
BDBM50272833

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 69655,50186329,50261811,50272833   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM69655
PNG
(1-N,4-N-dipyridin-2-ylbenzene-1,4-dicarboxamide | ...)
Show SMILES O=C(Nc1ccccn1)c1ccc(cc1)C(=O)Nc1ccccn1
Show InChI InChI=1S/C18H14N4O2/c23-17(21-15-5-1-3-11-19-15)13-7-9-14(10-8-13)18(24)22-16-6-2-4-12-20-16/h1-12H,(H,19,21,23)(H,20,22,24)
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MMDB

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PC cid
PC sid
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PCBioAssay
n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Luciferase


(Luciola lateralis)
BDBM50272833
PNG
(4-Amino-N-(5-phenylpyridin-2-yl)benzamide | CHEMBL...)
Show SMILES Nc1ccc(cc1)C(=O)Nc1ccc(cn1)-c1ccccc1
Show InChI InChI=1S/C18H15N3O/c19-16-9-6-14(7-10-16)18(22)21-17-11-8-15(12-20-17)13-4-2-1-3-5-13/h1-12H,19H2,(H,20,21,22)
PDB
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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Inhibition of firefly luciferase activity


J Med Chem 51: 4724-9 (2008)


Article DOI: 10.1021/jm8004509
BindingDB Entry DOI: 10.7270/Q2BP02MH
More data for this
Ligand-Target Pair
Luciferase


(Luciola lateralis)
BDBM50261811
PNG
(CHEMBL467379 | N-(5-Phenylpyridin-2-yl)benzamide)
Show SMILES O=C(Nc1ccc(cn1)-c1ccccc1)c1ccccc1
Show InChI InChI=1S/C18H14N2O/c21-18(15-9-5-2-6-10-15)20-17-12-11-16(13-19-17)14-7-3-1-4-8-14/h1-13H,(H,19,20,21)
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B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 69n/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Inhibition of firefly luciferase activity


J Med Chem 51: 4724-9 (2008)


Article DOI: 10.1021/jm8004509
BindingDB Entry DOI: 10.7270/Q2BP02MH
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50186329
PNG
(CHEMBL377136 | N-(pyridin-2-yl)benzamide | N-Pyrid...)
Show SMILES O=C(Nc1ccccn1)c1ccccc1
Show InChI InChI=1S/C12H10N2O/c15-12(10-6-2-1-3-7-10)14-11-8-4-5-9-13-11/h1-9H,(H,13,14,15)
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CHEMBL
PC cid
PC sid
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Patents


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Article
PubMed
n/an/a 9.54E+4n/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Inhibition of [3H]MPEP binding to mGluR5 in rat brain membrane


Bioorg Med Chem Lett 16: 3371-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.032
BindingDB Entry DOI: 10.7270/Q2RV0N9Z
More data for this
Ligand-Target Pair