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33 similar compounds to monomer 50007170

Wt: 415.5
BDBM72970
Purchase
Wt: 347.4
BDBM50007168
Wt: 347.4
BDBM50007185
Wt: 413.5
BDBM50026926
Wt: 357.4
BDBM50034281
Wt: 359.5
BDBM50034286
Wt: 385.5
BDBM50034290
Wt: 371.5
BDBM50034292
Wt: 331.4
BDBM50034295
Purchase
Wt: 399.5
BDBM50034302
Wt: 385.5
BDBM50034308
Wt: 345.4
BDBM50056034
Purchase
Wt: 399.5
BDBM50083044
Wt: 439.6
BDBM50083276
Wt: 397.5
BDBM50083277
Displayed 1 to 15 (of 33 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 72970,50007168,50007185,50026926,50034281,50034286,50034290,50034292,50034295,50034302,50034308,50056034,50083044,50083276,50083277   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034281
PNG
(Bicyclo[2.2.1]heptane-2-carboxylic acid {2-[4-(2-m...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CC3CCC2C3)CC1
Show InChI InChI=1S/C21H31N3O2/c1-26-20-5-3-2-4-19(20)24-12-10-23(11-13-24)9-8-22-21(25)18-15-16-6-7-17(18)14-16/h2-5,16-18H,6-15H2,1H3,(H,22,25)
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0.120n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034308
PNG
(Bicyclo[2.2.1]heptane-2-carboxylic acid {4-[4-(2-m...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C2CC3CCC2C3)CC1
Show InChI InChI=1S/C23H35N3O2/c1-28-22-7-3-2-6-21(22)26-14-12-25(13-15-26)11-5-4-10-24-23(27)20-17-18-8-9-19(20)16-18/h2-3,6-7,18-20H,4-5,8-17H2,1H3,(H,24,27)
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0.230n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034292
PNG
(CHEMBL25654 | Octahydro-pentalene-2-carboxylic aci...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CC3CCCC3C2)CC1
Show InChI InChI=1S/C22H33N3O2/c1-27-21-8-3-2-7-20(21)25-13-11-24(12-14-25)10-9-23-22(26)19-15-17-5-4-6-18(17)16-19/h2-3,7-8,17-19H,4-6,9-16H2,1H3,(H,23,26)
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0.240n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034302
PNG
(CHEMBL23877 | Octahydro-pentalene-2-carboxylic aci...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C2CC3CCCC3C2)CC1
Show InChI InChI=1S/C24H37N3O2/c1-29-23-10-3-2-9-22(23)27-15-13-26(14-16-27)12-5-4-11-25-24(28)21-17-19-7-6-8-20(19)18-21/h2-3,9-10,19-21H,4-8,11-18H2,1H3,(H,25,28)
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0.630n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056034
PNG
(CHEMBL108229 | Cyclohexanecarboxylic acid {2-[4-(2...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CCCCC2)CC1
Show InChI InChI=1S/C20H31N3O2/c1-25-19-10-6-5-9-18(19)23-15-13-22(14-16-23)12-11-21-20(24)17-7-3-2-4-8-17/h5-6,9-10,17H,2-4,7-8,11-16H2,1H3,(H,21,24)
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0.800n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...


J Med Chem 40: 300-12 (1997)


Article DOI: 10.1021/jm960496o
BindingDB Entry DOI: 10.7270/Q27W6B96
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50083277
PNG
(Adamantane-1-carboxylic acid {2-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1
Show InChI InChI=1S/C24H35N3O2/c1-29-22-5-3-2-4-21(22)27-10-8-26(9-11-27)7-6-25-23(28)24-15-18-12-19(16-24)14-20(13-18)17-24/h2-5,18-20H,6-17H2,1H3,(H,25,28)/t18-,19+,20-,24?
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1n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor


J Med Chem 42: 5077-94 (2000)


Article DOI: 10.1021/jm9806704
BindingDB Entry DOI: 10.7270/Q2C82B0P
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50007185
PNG
(CHEMBL21008 | N-{4-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C(C)(C)C)CC1
Show InChI InChI=1S/C20H33N3O2/c1-20(2,3)19(24)21-11-7-8-12-22-13-15-23(16-14-22)17-9-5-6-10-18(17)25-4/h5-6,9-10H,7-8,11-16H2,1-4H3,(H,21,24)
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1n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor of rat hippocampus using [3H]-8-hydroxy-2-(di-n-propylamine) tetralin (8-OH-DPAT) as a radio...


J Med Chem 34: 2633-8 (1991)


Article DOI: 10.1021/jm00112a043
BindingDB Entry DOI: 10.7270/Q2833R0C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034286
PNG
(CHEMBL23904 | Cyclopentanecarboxylic acid {4-[4-(2...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C2CCCC2)CC1
Show InChI InChI=1S/C21H33N3O2/c1-26-20-11-5-4-10-19(20)24-16-14-23(15-17-24)13-7-6-12-22-21(25)18-8-2-3-9-18/h4-5,10-11,18H,2-3,6-9,12-17H2,1H3,(H,22,25)
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1.88n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50083044
PNG
((3aS,7aR)-2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-y...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)[C@H]3CCCC[C@H]3C2=O)CC1
Show InChI InChI=1S/C23H33N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h4-5,10-11,18-19H,2-3,6-9,12-17H2,1H3/t18-,19+
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4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor


J Med Chem 42: 4952-60 (2000)


Article DOI: 10.1021/jm991045h
BindingDB Entry DOI: 10.7270/Q2833R7H
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50083276
PNG
(CHEMBL553514 | N-{3-[4-(2-Methoxy-phenyl)-piperazi...)
Show SMILES COc1ccccc1N1CCN(CCCNC(=O)CC23C[C@H]4C[C@H](C[C@](C)(C4)C2)C3)CC1
Show InChI InChI=1S/C27H41N3O2/c1-26-15-21-14-22(16-26)18-27(17-21,20-26)19-25(31)28-8-5-9-29-10-12-30(13-11-29)23-6-3-4-7-24(23)32-2/h3-4,6-7,21-22H,5,8-20H2,1-2H3,(H,28,31)/t21-,22+,26-,27?
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4.40n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor


J Med Chem 42: 5077-94 (2000)


Article DOI: 10.1021/jm9806704
BindingDB Entry DOI: 10.7270/Q2C82B0P
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034295
PNG
(CHEMBL23905 | Cyclopentanecarboxylic acid {2-[4-(2...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CCCC2)CC1
Show InChI InChI=1S/C19H29N3O2/c1-24-18-9-5-4-8-17(18)22-14-12-21(13-15-22)11-10-20-19(23)16-6-2-3-7-16/h4-5,8-9,16H,2-3,6-7,10-15H2,1H3,(H,20,23)
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4.68n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50007168
PNG
(CHEMBL27098 | Pentanoic acid {4-[4-(2-methoxy-phen...)
Show SMILES CCCCC(=O)NCCCCN1CCN(CC1)c1ccccc1OC
Show InChI InChI=1S/C20H33N3O2/c1-3-4-11-20(24)21-12-7-8-13-22-14-16-23(17-15-22)18-9-5-6-10-19(18)25-2/h5-6,9-10H,3-4,7-8,11-17H2,1-2H3,(H,21,24)
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7.5n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor of rat hippocampus using [3H]-8-hydroxy-2-(di-n-propylamine) tetralin (8-OH-DPAT) as a radio...


J Med Chem 34: 2633-8 (1991)


Article DOI: 10.1021/jm00112a043
BindingDB Entry DOI: 10.7270/Q2833R0C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034290
PNG
(CHEMBL280426 | Octahydro-pentalene-2-carboxylic ac...)
Show SMILES COc1ccccc1N1CCN(CCCNC(=O)C2CC3CCCC3C2)CC1
Show InChI InChI=1S/C23H35N3O2/c1-28-22-9-3-2-8-21(22)26-14-12-25(13-15-26)11-5-10-24-23(27)20-16-18-6-4-7-19(18)17-20/h2-3,8-9,18-20H,4-7,10-17H2,1H3,(H,24,27)
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11.6n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50007185
PNG
(CHEMBL21008 | N-{4-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C(C)(C)C)CC1
Show InChI InChI=1S/C20H33N3O2/c1-20(2,3)19(24)21-11-7-8-12-22-13-15-23(16-14-22)17-9-5-6-10-18(17)25-4/h5-6,9-10H,7-8,11-16H2,1-4H3,(H,21,24)
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13n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity at cloned human Dopamine receptor D4 expressed in HEK 293 cells, using [3H]nemonapride as radioligand


Citation and Details
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50007185
PNG
(CHEMBL21008 | N-{4-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C(C)(C)C)CC1
Show InChI InChI=1S/C20H33N3O2/c1-20(2,3)19(24)21-11-7-8-12-22-13-15-23(16-14-22)17-9-5-6-10-18(17)25-4/h5-6,9-10H,7-8,11-16H2,1-4H3,(H,21,24)
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20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity at cloned human Dopamine receptor D2 expressed in CHO cells, using [125I]iodosulpiride as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50056034
PNG
(CHEMBL108229 | Cyclohexanecarboxylic acid {2-[4-(2...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CCCCC2)CC1
Show InChI InChI=1S/C20H31N3O2/c1-25-19-10-6-5-9-18(19)23-15-13-22(14-16-23)12-11-21-20(24)17-7-3-2-4-8-17/h5-6,9-10,17H,2-4,7-8,11-16H2,1H3,(H,21,24)
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23n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
In vitro displacement of [3H]-spiperone from Dopamine receptor D2 binding site in rat striatum.


J Med Chem 40: 300-12 (1997)


Article DOI: 10.1021/jm960496o
BindingDB Entry DOI: 10.7270/Q27W6B96
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50083277
PNG
(Adamantane-1-carboxylic acid {2-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1
Show InChI InChI=1S/C24H35N3O2/c1-29-22-5-3-2-4-21(22)27-10-8-26(9-11-27)7-6-25-23(28)24-15-18-12-19(16-24)14-20(13-18)17-24/h2-5,18-20H,6-17H2,1H3,(H,25,28)/t18-,19+,20-,24?
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24n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Inhibitory activity against rat limbic tissue Dopamine receptor D2


J Med Chem 42: 5077-94 (2000)


Article DOI: 10.1021/jm9806704
BindingDB Entry DOI: 10.7270/Q2C82B0P
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50007185
PNG
(CHEMBL21008 | N-{4-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C(C)(C)C)CC1
Show InChI InChI=1S/C20H33N3O2/c1-20(2,3)19(24)21-11-7-8-12-22-13-15-23(16-14-22)17-9-5-6-10-18(17)25-4/h5-6,9-10H,7-8,11-16H2,1-4H3,(H,21,24)
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74n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity towards alpha-1 adrenergic receptor of rat frontal cortex using [3H]- WB- 4101 as a radioligand


J Med Chem 34: 2633-8 (1991)


Article DOI: 10.1021/jm00112a043
BindingDB Entry DOI: 10.7270/Q2833R0C
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50007168
PNG
(CHEMBL27098 | Pentanoic acid {4-[4-(2-methoxy-phen...)
Show SMILES CCCCC(=O)NCCCCN1CCN(CC1)c1ccccc1OC
Show InChI InChI=1S/C20H33N3O2/c1-3-4-11-20(24)21-12-7-8-13-22-14-16-23(17-15-22)18-9-5-6-10-19(18)25-2/h5-6,9-10H,3-4,7-8,11-17H2,1-2H3,(H,21,24)
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84n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity towards alpha-1 adrenergic receptor of rat frontal cortex using [3H]- WB- 4101 as a radioligand


J Med Chem 34: 2633-8 (1991)


Article DOI: 10.1021/jm00112a043
BindingDB Entry DOI: 10.7270/Q2833R0C
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50026926
PNG
(8-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CC1
Show InChI InChI=1S/C24H35N3O3/c1-30-21-9-3-2-8-20(21)26-16-14-25(15-17-26)12-6-7-13-27-22(28)18-24(19-23(27)29)10-4-5-11-24/h2-3,8-9H,4-7,10-19H2,1H3
MMDB

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n/an/a 51n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to dopamine receptor from rat corpus striatal membranes


J Med Chem 26: 194-203 (1983)


Article DOI: 10.1021/jm00356a014
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50026926
PNG
(8-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CC1
Show InChI InChI=1S/C24H35N3O3/c1-30-21-9-3-2-8-20(21)26-16-14-25(15-17-26)12-6-7-13-27-22(28)18-24(19-23(27)29)10-4-5-11-24/h2-3,8-9H,4-7,10-19H2,1H3
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n/an/a 13n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]WB-4101 binding to alpha-1-adrenergic receptor from rat cerebral cortex membranes


J Med Chem 26: 194-203 (1983)


Article DOI: 10.1021/jm00356a014
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50026926
PNG
(8-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CC1
Show InChI InChI=1S/C24H35N3O3/c1-30-21-9-3-2-8-20(21)26-16-14-25(15-17-26)12-6-7-13-27-22(28)18-24(19-23(27)29)10-4-5-11-24/h2-3,8-9H,4-7,10-19H2,1H3
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n/an/a 2n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to displace [3H]-8-OH-DPAT from serotonin 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes


Bioorg Med Chem Lett 6: 689-694 (1996)


Article DOI: 10.1016/0960-894X(96)00081-9
BindingDB Entry DOI: 10.7270/Q2JH3M5K
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50026926
PNG
(8-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CC1
Show InChI InChI=1S/C24H35N3O3/c1-30-21-9-3-2-8-20(21)26-16-14-25(15-17-26)12-6-7-13-27-22(28)18-24(19-23(27)29)10-4-5-11-24/h2-3,8-9H,4-7,10-19H2,1H3
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n/an/a 2n/an/an/an/an/an/a



ArQule Inc

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT in human CYP3A4 assay


Bioorg Med Chem Lett 14: 1709-12 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.045
BindingDB Entry DOI: 10.7270/Q2ZW1KB5
More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM72970
PNG
(MLS000936736 | N-[1-[4-(2-methoxyphenyl)-1-piperaz...)
Show SMILES COc1ccccc1N1CCN(CC1)C(=O)C(CC(C)C)NC(=O)C1CCCCC1
Show InChI InChI=1S/C24H37N3O3/c1-18(2)17-20(25-23(28)19-9-5-4-6-10-19)24(29)27-15-13-26(14-16-27)21-11-7-8-12-22(21)30-3/h7-8,11-12,18-20H,4-6,9-10,13-17H2,1-3H3,(H,25,28)
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n/an/an/an/a>2.60E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2P55KXK
More data for this
Ligand-Target Pair