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11 similar compounds to monomer 50447425

Compile data set for download or QSAR
Wt: 405.4
BDBM76212
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Wt: 405.4
BDBM76213
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Wt: 419.4
BDBM76221
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Wt: 403.4
BDBM50447416
Wt: 449.4
BDBM50447418
Wt: 433.4
BDBM50447419
Wt: 449.4
BDBM50447420
Wt: 407.4
BDBM50447421
Wt: 391.3
BDBM50447431
Wt: 405.4
BDBM50447448
Wt: 421.4
BDBM50447454

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 76212,76213,76221,50447416,50447418,50447419,50447420,50447421,50447431,50447448,50447454   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intestinal alkaline phosphatase


(Homo sapiens)
BDBM76212
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-15-5-3-2-4-12(15)11-19-17(22)8-9-20-28(24,25)13-6-7-14-16(10-13)27-18(23)21-14/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/an/an/a 4.51E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q29G5K8R
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM76212
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-15-5-3-2-4-12(15)11-19-17(22)8-9-20-28(24,25)13-6-7-14-16(10-13)27-18(23)21-14/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Homo sapiens)
BDBM76221
PNG
(MLS001096126 | N-(2-ethoxybenzyl)-3-[(2-keto-3H-1,...)
Show SMILES CCOc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C19H21N3O6S/c1-2-27-16-6-4-3-5-13(16)12-20-18(23)9-10-21-29(25,26)14-7-8-15-17(11-14)28-19(24)22-15/h3-8,11,21H,2,9-10,12H2,1H3,(H,20,23)(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2X63KDM
More data for this
Ligand-Target Pair
Alkaline phosphatase placental-like


(Homo sapiens)
BDBM76212
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-15-5-3-2-4-12(15)11-19-17(22)8-9-20-28(24,25)13-6-7-14-16(10-13)27-18(23)21-14/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/an/an/a 4.90E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2SJ1J25
More data for this
Ligand-Target Pair
Alkaline phosphatase placental-like


(Homo sapiens)
BDBM76213
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1cccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-3-12(9-13)11-19-17(22)7-8-20-28(24,25)14-5-6-15-16(10-14)27-18(23)21-15/h2-6,9-10,20H,7-8,11H2,1H3,(H,19,22)(H,21,23)
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n/an/an/an/a>1.00E+5n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2SJ1J25
More data for this
Ligand-Target Pair
Alkaline phosphatase placental-like


(Homo sapiens)
BDBM76221
PNG
(MLS001096126 | N-(2-ethoxybenzyl)-3-[(2-keto-3H-1,...)
Show SMILES CCOc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C19H21N3O6S/c1-2-27-16-6-4-3-5-13(16)12-20-18(23)9-10-21-29(25,26)14-7-8-15-17(11-14)28-19(24)22-15/h3-8,11,21H,2,9-10,12H2,1H3,(H,20,23)(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2NS0SCW
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM76212
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-15-5-3-2-4-12(15)11-19-17(22)8-9-20-28(24,25)13-6-7-14-16(10-13)27-18(23)21-14/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a 2.75E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2H130G1
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM76213
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1cccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-3-12(9-13)11-19-17(22)7-8-20-28(24,25)14-5-6-15-16(10-14)27-18(23)21-15/h2-6,9-10,20H,7-8,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a 6.32E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2H130G1
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM76221
PNG
(MLS001096126 | N-(2-ethoxybenzyl)-3-[(2-keto-3H-1,...)
Show SMILES CCOc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C19H21N3O6S/c1-2-27-16-6-4-3-5-13(16)12-20-18(23)9-10-21-29(25,26)14-7-8-15-17(11-14)28-19(24)22-15/h3-8,11,21H,2,9-10,12H2,1H3,(H,20,23)(H,22,24)
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n/an/a 2.27E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2H130G1
More data for this
Ligand-Target Pair
Alpi


(Rattus norvegicus (Rat))
BDBM76212
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-15-5-3-2-4-12(15)11-19-17(22)8-9-20-28(24,25)13-6-7-14-16(10-13)27-18(23)21-14/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a 1.14E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2DB809V
More data for this
Ligand-Target Pair
Alpi


(Rattus norvegicus (Rat))
BDBM76213
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1cccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-3-12(9-13)11-19-17(22)7-8-20-28(24,25)14-5-6-15-16(10-14)27-18(23)21-15/h2-6,9-10,20H,7-8,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a 1.39E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2DB809V
More data for this
Ligand-Target Pair
Alpi


(Rattus norvegicus (Rat))
BDBM76221
PNG
(MLS001096126 | N-(2-ethoxybenzyl)-3-[(2-keto-3H-1,...)
Show SMILES CCOc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C19H21N3O6S/c1-2-27-16-6-4-3-5-13(16)12-20-18(23)9-10-21-29(25,26)14-7-8-15-17(11-14)28-19(24)22-15/h3-8,11,21H,2,9-10,12H2,1H3,(H,20,23)(H,22,24)
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n/an/a 2.65E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2DB809V
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM50447416
PNG
(CHEMBL3115147)
Show SMILES Cc1ccccc1CNC(=O)CCCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C19H21N3O5S/c1-13-5-2-3-6-14(13)12-20-18(23)7-4-10-21-28(25,26)15-8-9-16-17(11-15)27-19(24)22-16/h2-3,5-6,8-9,11,21H,4,7,10,12H2,1H3,(H,20,23)(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM50447418
PNG
(CHEMBL3115145)
Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1OC
Show InChI InChI=1S/C20H23N3O7S/c1-28-16-8-5-13(10-18(16)29-2)12-21-19(24)4-3-9-22-31(26,27)14-6-7-15-17(11-14)30-20(25)23-15/h5-8,10-11,22H,3-4,9,12H2,1-2H3,(H,21,24)(H,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM50447419
PNG
(CHEMBL3115144)
Show SMILES O=C(CCCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1)NCc1ccc2OCOc2c1
Show InChI InChI=1S/C19H19N3O7S/c23-18(20-10-12-3-6-15-17(8-12)28-11-27-15)2-1-7-21-30(25,26)13-4-5-14-16(9-13)29-19(24)22-14/h3-6,8-9,21H,1-2,7,10-11H2,(H,20,23)(H,22,24)
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Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM50447420
PNG
(CHEMBL3115143)
Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(OC)c1
Show InChI InChI=1S/C20H23N3O7S/c1-28-14-6-5-13(17(10-14)29-2)12-21-19(24)4-3-9-22-31(26,27)15-7-8-16-18(11-15)30-20(25)23-16/h5-8,10-11,22H,3-4,9,12H2,1-2H3,(H,21,24)(H,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM50447421
PNG
(CHEMBL3115142)
Show SMILES Fc1cccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H18FN3O5S/c19-13-4-1-3-12(9-13)11-20-17(23)5-2-8-21-28(25,26)14-6-7-15-16(10-14)27-18(24)22-15/h1,3-4,6-7,9-10,21H,2,5,8,11H2,(H,20,23)(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM50447431
PNG
(CHEMBL3115132)
Show SMILES Oc1ccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1
Show InChI InChI=1S/C17H17N3O6S/c21-12-3-1-11(2-4-12)10-18-16(22)7-8-19-27(24,25)13-5-6-14-15(9-13)26-17(23)20-14/h1-6,9,19,21H,7-8,10H2,(H,18,22)(H,20,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM76212
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-15-5-3-2-4-12(15)11-19-17(22)8-9-20-28(24,25)13-6-7-14-16(10-13)27-18(23)21-14/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM76213
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1cccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-3-12(9-13)11-19-17(22)7-8-20-28(24,25)14-5-6-15-16(10-14)27-18(23)21-15/h2-6,9-10,20H,7-8,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM50447448
PNG
(CHEMBL3115121)
Show SMILES COc1ccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-12(3-5-13)11-19-17(22)8-9-20-28(24,25)14-6-7-15-16(10-14)27-18(23)21-15/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase placental type


(Homo sapiens)
BDBM50447454
PNG
(CHEMBL3114960)
Show SMILES COc1ccc(CNC(=O)CNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(OC)c1
Show InChI InChI=1S/C18H19N3O7S/c1-26-12-4-3-11(15(7-12)27-2)9-19-17(22)10-20-29(24,25)13-5-6-14-16(8-13)28-18(23)21-14/h3-8,20H,9-10H2,1-2H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM76213
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1cccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-3-12(9-13)11-19-17(22)7-8-20-28(24,25)14-5-6-15-16(10-14)27-18(23)21-15/h2-6,9-10,20H,7-8,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50447448
PNG
(CHEMBL3115121)
Show SMILES COc1ccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-12(3-5-13)11-19-17(22)8-9-20-28(24,25)14-6-7-15-16(10-14)27-18(23)21-15/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50447454
PNG
(CHEMBL3114960)
Show SMILES COc1ccc(CNC(=O)CNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(OC)c1
Show InChI InChI=1S/C18H19N3O7S/c1-26-12-4-3-11(15(7-12)27-2)9-19-17(22)10-20-29(24,25)13-5-6-14-16(8-13)28-18(23)21-14/h3-8,20H,9-10H2,1-2H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM50447416
PNG
(CHEMBL3115147)
Show SMILES Cc1ccccc1CNC(=O)CCCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C19H21N3O5S/c1-13-5-2-3-6-14(13)12-20-18(23)7-4-10-21-28(25,26)15-8-9-16-17(11-15)27-19(24)22-16/h2-3,5-6,8-9,11,21H,4,7,10,12H2,1H3,(H,20,23)(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM50447418
PNG
(CHEMBL3115145)
Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1OC
Show InChI InChI=1S/C20H23N3O7S/c1-28-16-8-5-13(10-18(16)29-2)12-21-19(24)4-3-9-22-31(26,27)14-6-7-15-17(11-14)30-20(25)23-15/h5-8,10-11,22H,3-4,9,12H2,1-2H3,(H,21,24)(H,23,25)
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n/an/a 7.80E+4n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM50447419
PNG
(CHEMBL3115144)
Show SMILES O=C(CCCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1)NCc1ccc2OCOc2c1
Show InChI InChI=1S/C19H19N3O7S/c23-18(20-10-12-3-6-15-17(8-12)28-11-27-15)2-1-7-21-30(25,26)13-4-5-14-16(9-13)29-19(24)22-14/h3-6,8-9,21H,1-2,7,10-11H2,(H,20,23)(H,22,24)
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n/an/a 4.50E+4n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM50447420
PNG
(CHEMBL3115143)
Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(OC)c1
Show InChI InChI=1S/C20H23N3O7S/c1-28-14-6-5-13(17(10-14)29-2)12-21-19(24)4-3-9-22-31(26,27)15-7-8-16-18(11-15)30-20(25)23-16/h5-8,10-11,22H,3-4,9,12H2,1-2H3,(H,21,24)(H,23,25)
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n/an/a 3.70E+4n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM50447421
PNG
(CHEMBL3115142)
Show SMILES Fc1cccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H18FN3O5S/c19-13-4-1-3-12(9-13)11-20-17(23)5-2-8-21-28(25,26)14-6-7-15-16(10-14)27-18(24)22-15/h1,3-4,6-7,9-10,21H,2,5,8,11H2,(H,20,23)(H,22,24)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM50447431
PNG
(CHEMBL3115132)
Show SMILES Oc1ccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1
Show InChI InChI=1S/C17H17N3O6S/c21-12-3-1-11(2-4-12)10-18-16(22)7-8-19-27(24,25)13-5-6-14-15(9-13)26-17(23)20-14/h1-6,9,19,21H,7-8,10H2,(H,18,22)(H,20,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM76212
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-15-5-3-2-4-12(15)11-19-17(22)8-9-20-28(24,25)13-6-7-14-16(10-13)27-18(23)21-14/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM76213
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1cccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-3-12(9-13)11-19-17(22)7-8-20-28(24,25)14-5-6-15-16(10-14)27-18(23)21-15/h2-6,9-10,20H,7-8,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM50447448
PNG
(CHEMBL3115121)
Show SMILES COc1ccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-12(3-5-13)11-19-17(22)8-9-20-28(24,25)14-6-7-15-16(10-14)27-18(23)21-15/h2-7,10,20H,8-9,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a 2.30E+3n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Mus musculus)
BDBM50447454
PNG
(CHEMBL3114960)
Show SMILES COc1ccc(CNC(=O)CNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(OC)c1
Show InChI InChI=1S/C18H19N3O7S/c1-26-12-4-3-11(15(7-12)27-2)9-19-17(22)10-20-29(24,25)13-5-6-14-16(8-13)28-18(23)21-14/h3-8,20H,9-10H2,1-2H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50447416
PNG
(CHEMBL3115147)
Show SMILES Cc1ccccc1CNC(=O)CCCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C19H21N3O5S/c1-13-5-2-3-6-14(13)12-20-18(23)7-4-10-21-28(25,26)15-8-9-16-17(11-15)27-19(24)22-16/h2-3,5-6,8-9,11,21H,4,7,10,12H2,1H3,(H,20,23)(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50447418
PNG
(CHEMBL3115145)
Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1OC
Show InChI InChI=1S/C20H23N3O7S/c1-28-16-8-5-13(10-18(16)29-2)12-21-19(24)4-3-9-22-31(26,27)14-6-7-15-17(11-14)30-20(25)23-15/h5-8,10-11,22H,3-4,9,12H2,1-2H3,(H,21,24)(H,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50447419
PNG
(CHEMBL3115144)
Show SMILES O=C(CCCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1)NCc1ccc2OCOc2c1
Show InChI InChI=1S/C19H19N3O7S/c23-18(20-10-12-3-6-15-17(8-12)28-11-27-15)2-1-7-21-30(25,26)13-4-5-14-16(9-13)29-19(24)22-14/h3-6,8-9,21H,1-2,7,10-11H2,(H,20,23)(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50447420
PNG
(CHEMBL3115143)
Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(OC)c1
Show InChI InChI=1S/C20H23N3O7S/c1-28-14-6-5-13(17(10-14)29-2)12-21-19(24)4-3-9-22-31(26,27)15-7-8-16-18(11-15)30-20(25)23-16/h5-8,10-11,22H,3-4,9,12H2,1-2H3,(H,21,24)(H,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50447421
PNG
(CHEMBL3115142)
Show SMILES Fc1cccc(CNC(=O)CCCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H18FN3O5S/c19-13-4-1-3-12(9-13)11-20-17(23)5-2-8-21-28(25,26)14-6-7-15-16(10-14)27-18(24)22-15/h1,3-4,6-7,9-10,21H,2,5,8,11H2,(H,20,23)(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50447431
PNG
(CHEMBL3115132)
Show SMILES Oc1ccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1
Show InChI InChI=1S/C17H17N3O6S/c21-12-3-1-11(2-4-12)10-18-16(22)7-8-19-27(24,25)13-5-6-14-15(9-13)26-17(23)20-14/h1-6,9,19,21H,7-8,10H2,(H,18,22)(H,20,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay


Bioorg Med Chem Lett 24: 1000-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.043
BindingDB Entry DOI: 10.7270/Q2ST7RB8
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Homo sapiens)
BDBM76213
PNG
(3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N...)
Show SMILES COc1cccc(CNC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
Show InChI InChI=1S/C18H19N3O6S/c1-26-13-4-2-3-12(9-13)11-19-17(22)7-8-20-28(24,25)14-5-6-15-16(10-14)27-18(23)21-15/h2-6,9-10,20H,7-8,11H2,1H3,(H,19,22)(H,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2X63KDM
More data for this
Ligand-Target Pair