BindingDB logo
myBDB logout

50 similar compounds to monomer 50105887

Compile data set for download or QSAR
Wt: 6956.5
BDBM82544
Wt: 1533.7
BDBM50001520
Wt: 1483.7
BDBM50001505
Wt: 1533.7
BDBM50001518
Wt: 1483.7
BDBM50001519
Wt: 1126.2
BDBM50105883
Wt: 1504.6
BDBM50131872
Wt: 1590.8
BDBM50131874
Wt: 1511.7
BDBM50131875
Wt: 1533.7
BDBM50131878
Wt: 1561.8
BDBM50131880
Wt: 1096.2
BDBM50158406
Wt: 1606.7
BDBM50159042
Wt: 1581.8
BDBM50159052
Wt: 1491.6
BDBM50159053
Displayed 1 to 15 (of 50 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 67 hits for monomerid = 82544,50001520,50001505,50001518,50001519,50105883,50131872,50131874,50131875,50131878,50131880,50158406,50159042,50159052,50159053   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50105883
PNG
(3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-prop...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(N)=O
Show InChI InChI=1S/C51H63N15O11S2/c1-27(67)60-41-25-79-78-24-40(44(52)71)61-42(68)23-58-45(72)38(19-31-21-57-34-10-5-4-9-33(31)34)65-46(73)35(11-6-16-56-51(53)54)62-48(75)37(18-28-12-13-29-7-2-3-8-30(29)17-28)64-49(76)39(20-32-22-55-26-59-32)66-47(74)36(63-50(41)77)14-15-43(69)70/h2-5,7-10,12-13,17,21-22,26,35-41,57H,6,11,14-16,18-20,23-25H2,1H3,(H2,52,71)(H,55,59)(H,58,72)(H,60,67)(H,61,68)(H,62,75)(H,63,77)(H,64,76)(H,65,73)(H,66,74)(H,69,70)(H4,53,54,56)/t35-,36+,37-,38+,39-,40-,41+/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.390n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against human melanocortin receptor 5 (hMC5R) (concentration of the peptide at 50% specific binding)


J Med Chem 44: 3665-72 (2001)


Article DOI: 10.1021/jm010165y
BindingDB Entry DOI: 10.7270/Q2RF5T9S
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50105883
PNG
(3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-prop...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(N)=O
Show InChI InChI=1S/C51H63N15O11S2/c1-27(67)60-41-25-79-78-24-40(44(52)71)61-42(68)23-58-45(72)38(19-31-21-57-34-10-5-4-9-33(31)34)65-46(73)35(11-6-16-56-51(53)54)62-48(75)37(18-28-12-13-29-7-2-3-8-30(29)17-28)64-49(76)39(20-32-22-55-26-59-32)66-47(74)36(63-50(41)77)14-15-43(69)70/h2-5,7-10,12-13,17,21-22,26,35-41,57H,6,11,14-16,18-20,23-25H2,1H3,(H2,52,71)(H,55,59)(H,58,72)(H,60,67)(H,61,68)(H,62,75)(H,63,77)(H,64,76)(H,65,73)(H,66,74)(H,69,70)(H4,53,54,56)/t35-,36+,37-,38+,39-,40-,41+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.570n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against human melanocortin receptor 4 (hMC4R) (concentration of the peptide at 50% specific binding)


J Med Chem 44: 3665-72 (2001)


Article DOI: 10.1021/jm010165y
BindingDB Entry DOI: 10.7270/Q2RF5T9S
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50105883
PNG
(3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-prop...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(N)=O
Show InChI InChI=1S/C51H63N15O11S2/c1-27(67)60-41-25-79-78-24-40(44(52)71)61-42(68)23-58-45(72)38(19-31-21-57-34-10-5-4-9-33(31)34)65-46(73)35(11-6-16-56-51(53)54)62-48(75)37(18-28-12-13-29-7-2-3-8-30(29)17-28)64-49(76)39(20-32-22-55-26-59-32)66-47(74)36(63-50(41)77)14-15-43(69)70/h2-5,7-10,12-13,17,21-22,26,35-41,57H,6,11,14-16,18-20,23-25H2,1H3,(H2,52,71)(H,55,59)(H,58,72)(H,60,67)(H,61,68)(H,62,75)(H,63,77)(H,64,76)(H,65,73)(H,66,74)(H,69,70)(H4,53,54,56)/t35-,36+,37-,38+,39-,40-,41+/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.60n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against human melanocortin receptor 3 (hMC3R) (concentration of the peptide at 50% specific binding)


J Med Chem 44: 3665-72 (2001)


Article DOI: 10.1021/jm010165y
BindingDB Entry DOI: 10.7270/Q2RF5T9S
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131874
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Gly-Cys]-Pro-Pr...)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H99N19O17S2/c1-41(94)48-38-111-112-39-57(73(110)93-26-10-18-59(93)62(97)37-92-25-9-17-58(92)61(96)35-82-50(15-6-7-23-75)60(95)34-83-53(66(76)103)31-65(101)102)86-63(98)36-84-68(105)55(29-45-32-81-49-14-5-4-13-47(45)49)90-69(106)51(16-8-24-80-74(77)78)88-71(108)54(28-42-19-20-43-11-2-3-12-44(43)27-42)89-72(109)56(30-46-33-79-40-85-46)91-70(107)52(87-67(48)104)21-22-64(99)100/h2-5,11-14,19-20,27,32-33,40,48,50-59,81-83H,6-10,15-18,21-26,28-31,34-39,75H2,1H3,(H2,76,103)(H,79,85)(H,84,105)(H,86,98)(H,87,104)(H,88,108)(H,89,109)(H,90,106)(H,91,107)(H,99,100)(H,101,102)(H4,77,78,80)/t48-,50-,51-,52+,53-,54-,55+,56-,57-,58-,59-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.10n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibitory activity against human melanocortin receptor human Melanocortin 4 receptor was determined


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131874
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Gly-Cys]-Pro-Pr...)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H99N19O17S2/c1-41(94)48-38-111-112-39-57(73(110)93-26-10-18-59(93)62(97)37-92-25-9-17-58(92)61(96)35-82-50(15-6-7-23-75)60(95)34-83-53(66(76)103)31-65(101)102)86-63(98)36-84-68(105)55(29-45-32-81-49-14-5-4-13-47(45)49)90-69(106)51(16-8-24-80-74(77)78)88-71(108)54(28-42-19-20-43-11-2-3-12-44(43)27-42)89-72(109)56(30-46-33-79-40-85-46)91-70(107)52(87-67(48)104)21-22-64(99)100/h2-5,11-14,19-20,27,32-33,40,48,50-59,81-83H,6-10,15-18,21-26,28-31,34-39,75H2,1H3,(H2,76,103)(H,79,85)(H,84,105)(H,86,98)(H,87,104)(H,88,108)(H,89,109)(H,90,106)(H,91,107)(H,99,100)(H,101,102)(H4,77,78,80)/t48-,50-,51-,52+,53-,54-,55+,56-,57-,58-,59-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
54n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibitory activity against human Melanocortin 3 receptor was determined


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50131874
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Gly-Cys]-Pro-Pr...)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H99N19O17S2/c1-41(94)48-38-111-112-39-57(73(110)93-26-10-18-59(93)62(97)37-92-25-9-17-58(92)61(96)35-82-50(15-6-7-23-75)60(95)34-83-53(66(76)103)31-65(101)102)86-63(98)36-84-68(105)55(29-45-32-81-49-14-5-4-13-47(45)49)90-69(106)51(16-8-24-80-74(77)78)88-71(108)54(28-42-19-20-43-11-2-3-12-44(43)27-42)89-72(109)56(30-46-33-79-40-85-46)91-70(107)52(87-67(48)104)21-22-64(99)100/h2-5,11-14,19-20,27,32-33,40,48,50-59,81-83H,6-10,15-18,21-26,28-31,34-39,75H2,1H3,(H2,76,103)(H,79,85)(H,84,105)(H,86,98)(H,87,104)(H,88,108)(H,89,109)(H,90,106)(H,91,107)(H,99,100)(H,101,102)(H4,77,78,80)/t48-,50-,51-,52+,53-,54-,55+,56-,57-,58-,59-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
649n/an/an/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibitory activity against human melanocortin receptor human Melanocortin 5 receptor was determined


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
n-AChR


(RAT)
BDBM82544
PNG
(Alpha-Cobratoxin | CAS_69344-74-7 | COBRATOXIN)
Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CS)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C277H443N97O98S8/c1-17-121(7)207(261(461)339-156(62-69-203(411)412)235(435)364-208(122(8)18-2)262(462)349-165(90-190(288)395)244(444)360-179(114-478)255(455)361-180(115-479)256(456)367-213(127(13)383)266(466)370-212(126(12)382)265(465)351-168(94-205(415)416)246(446)333-148(44-31-77-309-276(299)300)228(428)357-177(112-476)254(454)347-164(89-189(287)394)243(443)352-169(271(471)472)92-192(290)397)362-199(404)104-316-220(420)162(87-187(285)392)345-225(425)145(39-23-26-72-280)338-260(460)206(120(5)6)363-250(450)173(108-378)356-257(457)182-46-33-79-373(182)269(469)181(116-480)325-198(403)102-317-222(422)174(109-473)323-196(401)101-315-218(418)141(40-27-73-305-272(291)292)327-230(430)155(61-68-202(409)410)340-263(463)210(124(10)380)365-233(433)149(45-32-78-310-277(301)302)334-237(437)157(82-131-48-52-136(387)53-49-131)322-195(400)100-314-219(419)142(41-28-74-306-273(293)294)328-240(440)160(85-134-96-303-117-319-134)343-247(447)167(93-204(413)414)348-227(427)147(43-30-76-308-275(297)298)332-239(439)159(84-133-95-311-140-36-20-19-35-138(133)140)342-226(426)146(42-29-75-307-274(295)296)330-223(423)143(37-21-24-70-278)329-224(424)144(38-22-25-71-279)331-238(438)158(83-132-50-54-137(388)55-51-132)341-252(452)178(113-477)359-245(445)166(91-191(289)396)350-264(464)211(125(11)381)366-234(434)150(59-66-200(405)406)321-194(399)99-312-193(398)98-313-221(421)170(105-375)353-251(451)175(110-474)324-197(402)103-318-259(459)209(123(9)379)369-268(468)215(129(15)385)371-267(467)214(128(14)384)368-258(458)183-47-34-80-374(183)270(470)216(130(16)386)372-236(436)153(58-65-186(284)391)337-248(448)171(106-376)355-249(449)172(107-377)354-231(431)152(57-64-185(283)390)335-229(429)151(56-63-184(282)389)336-242(442)163(88-188(286)393)346-241(441)161(86-135-97-304-118-320-135)344-253(453)176(111-475)358-232(432)154(60-67-201(407)408)326-217(417)139(281)81-119(3)4/h19-20,35-36,48-55,95-97,117-130,139,141-183,206-216,311,375-388,473-480H,17-18,21-34,37-47,56-94,98-116,278-281H2,1-16H3,(H2,282,389)(H2,283,390)(H2,284,391)(H2,285,392)(H2,286,393)(H2,287,394)(H2,288,395)(H2,289,396)(H2,290,397)(H,303,319)(H,304,320)(H,312,398)(H,313,421)(H,314,419)(H,315,418)(H,316,420)(H,317,422)(H,318,459)(H,321,399)(H,322,400)(H,323,401)(H,324,402)(H,325,403)(H,326,417)(H,327,430)(H,328,440)(H,329,424)(H,330,423)(H,331,438)(H,332,439)(H,333,446)(H,334,437)(H,335,429)(H,336,442)(H,337,448)(H,338,460)(H,339,461)(H,340,463)(H,341,452)(H,342,426)(H,343,447)(H,344,453)(H,345,425)(H,346,441)(H,347,454)(H,348,427)(H,349,462)(H,350,464)(H,351,465)(H,352,443)(H,353,451)(H,354,431)(H,355,449)(H,356,457)(H,357,428)(H,358,432)(H,359,445)(H,360,444)(H,361,455)(H,362,404)(H,363,450)(H,364,435)(H,365,433)(H,366,434)(H,367,456)(H,368,458)(H,369,468)(H,370,466)(H,371,467)(H,372,436)(H,405,406)(H,407,408)(H,409,410)(H,411,412)(H,413,414)(H,415,416)(H,471,472)(H4,291,292,305)(H4,293,294,306)(H4,295,296,307)(H4,297,298,308)(H4,299,300,309)(H4,301,302,310)/t121-,122-,123+,124+,125+,126+,127+,128+,129+,130+,139-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,206-,207-,208-,209-,210-,211-,212-,213-,214-,215-,216-/m0/s1
GoogleScholar
KEGG
PC cid
PC sid
UniChem

Similars

PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of California

Curated by PDSP Ki Database




J Pharmacol Exp Ther 270: 159-66 (1994)


BindingDB Entry DOI: 10.7270/Q22Z141C
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50131874
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Gly-Cys]-Pro-Pr...)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H99N19O17S2/c1-41(94)48-38-111-112-39-57(73(110)93-26-10-18-59(93)62(97)37-92-25-9-17-58(92)61(96)35-82-50(15-6-7-23-75)60(95)34-83-53(66(76)103)31-65(101)102)86-63(98)36-84-68(105)55(29-45-32-81-49-14-5-4-13-47(45)49)90-69(106)51(16-8-24-80-74(77)78)88-71(108)54(28-42-19-20-43-11-2-3-12-44(43)27-42)89-72(109)56(30-46-33-79-40-85-46)91-70(107)52(87-67(48)104)21-22-64(99)100/h2-5,11-14,19-20,27,32-33,40,48,50-59,81-83H,6-10,15-18,21-26,28-31,34-39,75H2,1H3,(H2,76,103)(H,79,85)(H,84,105)(H,86,98)(H,87,104)(H,88,108)(H,89,109)(H,90,106)(H,91,107)(H,99,100)(H,101,102)(H4,77,78,80)/t48-,50-,51-,52+,53-,54-,55+,56-,57-,58-,59-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity against human Melanocortin 5 receptor


J Med Chem 45: 5287-94 (2002)


Article DOI: 10.1021/jm0202526
BindingDB Entry DOI: 10.7270/Q20G3KW8
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131874
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Gly-Cys]-Pro-Pr...)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H99N19O17S2/c1-41(94)48-38-111-112-39-57(73(110)93-26-10-18-59(93)62(97)37-92-25-9-17-58(92)61(96)35-82-50(15-6-7-23-75)60(95)34-83-53(66(76)103)31-65(101)102)86-63(98)36-84-68(105)55(29-45-32-81-49-14-5-4-13-47(45)49)90-69(106)51(16-8-24-80-74(77)78)88-71(108)54(28-42-19-20-43-11-2-3-12-44(43)27-42)89-72(109)56(30-46-33-79-40-85-46)91-70(107)52(87-67(48)104)21-22-64(99)100/h2-5,11-14,19-20,27,32-33,40,48,50-59,81-83H,6-10,15-18,21-26,28-31,34-39,75H2,1H3,(H2,76,103)(H,79,85)(H,84,105)(H,86,98)(H,87,104)(H,88,108)(H,89,109)(H,90,106)(H,91,107)(H,99,100)(H,101,102)(H4,77,78,80)/t48-,50-,51-,52+,53-,54-,55+,56-,57-,58-,59-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity for human Melanocortin-3 receptor


J Med Chem 45: 5287-94 (2002)


Article DOI: 10.1021/jm0202526
BindingDB Entry DOI: 10.7270/Q20G3KW8
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50001518
PNG
(CHEMBL2112603)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49+,50+,51-,52+,53+,54-,55+,56-,57+,58+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human Melanocortin 3 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50001518
PNG
(CHEMBL2112603)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49+,50+,51-,52+,53+,54-,55+,56-,57+,58+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50001505
PNG
(CHEMBL2112604)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45+,46+,47-,48+,49+,50-,51+,52-,53+,54+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50001505
PNG
(CHEMBL2112604)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45+,46+,47-,48+,49+,50-,51+,52-,53+,54+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 620n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human Melanocortin 3 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50001518
PNG
(CHEMBL2112603)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49+,50+,51-,52+,53+,54-,55+,56-,57+,58+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 5 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50001518
PNG
(CHEMBL2112603)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49+,50+,51-,52+,53+,54-,55+,56-,57+,58+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 880n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation (10e-10 to 10e-4 M)


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50001505
PNG
(CHEMBL2112604)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45+,46+,47-,48+,49+,50-,51+,52-,53+,54+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 73n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 5 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50001519
PNG
(CHEMBL2111808)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45-,46-,47+,48-,49-,50+,51-,52-,53-,54-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 4 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50001520
PNG
(CHEMBL2111807)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49-,50-,51+,52-,53-,54+,55-,56-,57-,58-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.40n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 4 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50001519
PNG
(CHEMBL2111808)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45-,46-,47+,48-,49-,50+,51-,52-,53-,54-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50001520
PNG
(CHEMBL2111807)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49-,50-,51+,52-,53-,54+,55-,56-,57-,58-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 6.10n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131875
PNG
(Ac-c[Pen-Glu-His-D-Phe-Arg-Trp-Cys]-Pro-Pro-Lys-As...)
Show SMILES CC(=O)C1C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NC(CSSC1(C)C)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C70H98N18O16S2/c1-39(89)60-67(103)82-47(22-23-58(93)94)63(99)85-51(30-42-33-75-38-80-42)66(102)83-49(28-40-14-5-4-6-15-40)64(100)81-46(19-11-25-76-69(73)74)62(98)84-50(29-41-32-77-44-17-8-7-16-43(41)44)65(101)86-52(37-105-106-70(60,2)3)68(104)88-27-13-21-54(88)57(92)36-87-26-12-20-53(87)56(91)35-78-45(18-9-10-24-71)55(90)34-79-48(61(72)97)31-59(95)96/h4-8,14-17,32-33,38,45-54,60,77-79H,9-13,18-31,34-37,71H2,1-3H3,(H2,72,97)(H,75,80)(H,81,100)(H,82,103)(H,83,102)(H,84,98)(H,85,99)(H,86,101)(H,93,94)(H,95,96)(H4,73,74,76)/t45-,46-,47+,48-,49-,50+,51-,52?,53-,54-,60?/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.80n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131872
PNG
(Ac-c[Asp-Glu-His-D-Phe-Arg-Trp-Lys]-Pro-Pro-Lys-As...)
Show SMILES CC(=O)[C@@H]1CC(=O)NCCCC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H101N19O17/c1-41(92)46-33-61(96)78-26-10-8-19-51(71(108)91-29-13-22-57(91)60(95)39-90-28-12-21-56(90)59(94)38-81-48(18-7-9-25-73)58(93)37-82-52(64(74)101)34-63(99)100)86-69(106)54(31-43-35-80-47-17-6-5-16-45(43)47)88-66(103)49(20-11-27-79-72(75)76)85-68(105)53(30-42-14-3-2-4-15-42)87-70(107)55(32-44-36-77-40-83-44)89-67(104)50(84-65(46)102)23-24-62(97)98/h2-6,14-17,35-36,40,46,48-57,80-82H,7-13,18-34,37-39,73H2,1H3,(H2,74,101)(H,77,83)(H,78,96)(H,84,102)(H,85,105)(H,86,106)(H,87,107)(H,88,103)(H,89,104)(H,97,98)(H,99,100)(H4,75,76,79)/t46-,48-,49-,50+,51+,52-,53-,54+,55-,56-,57-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131878
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-D-Cys]-Pro-Pro-...)
Show SMILES CC(=O)C1CSSCC(NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47?,49-,50-,51+,52-,53-,54+,55-,56?,57-,58-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50001519
PNG
(CHEMBL2111808)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45-,46-,47+,48-,49-,50+,51-,52-,53-,54-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50001520
PNG
(CHEMBL2111807)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49-,50-,51+,52-,53-,54+,55-,56-,57-,58-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 190n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50001505
PNG
(CHEMBL2112604)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45+,46+,47-,48+,49+,50-,51+,52-,53+,54+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50001518
PNG
(CHEMBL2112603)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49+,50+,51-,52+,53+,54-,55+,56-,57+,58+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131880
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Cys]-Pro-Pro-Ly...)
Show SMILES CC(=O)C1C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NC(CSSC1(C)C)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H100N18O16S2/c1-41(93)64-71(107)86-51(23-24-62(97)98)67(103)89-55(32-46-35-79-40-84-46)70(106)87-53(30-42-21-22-43-13-4-5-14-44(43)29-42)68(104)85-50(18-10-26-80-73(77)78)66(102)88-54(31-45-34-81-48-16-7-6-15-47(45)48)69(105)90-56(39-109-110-74(64,2)3)72(108)92-28-12-20-58(92)61(96)38-91-27-11-19-57(91)60(95)37-82-49(17-8-9-25-75)59(94)36-83-52(65(76)101)33-63(99)100/h4-7,13-16,21-22,29,34-35,40,49-58,64,81-83H,8-12,17-20,23-28,30-33,36-39,75H2,1-3H3,(H2,76,101)(H,79,84)(H,85,104)(H,86,107)(H,87,106)(H,88,102)(H,89,103)(H,90,105)(H,97,98)(H,99,100)(H4,77,78,80)/t49-,50-,51+,52-,53-,54+,55-,56?,57-,58-,64?/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50001505
PNG
(CHEMBL2112604)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45+,46+,47-,48+,49+,50-,51+,52-,53+,54+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.70E+4n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 4 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50001518
PNG
(CHEMBL2112603)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49+,50+,51-,52+,53+,54-,55+,56-,57+,58+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 4 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50131878
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-D-Cys]-Pro-Pro-...)
Show SMILES CC(=O)C1CSSCC(NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47?,49-,50-,51+,52-,53-,54+,55-,56?,57-,58-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 5 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50001520
PNG
(CHEMBL2111807)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49-,50-,51+,52-,53-,54+,55-,56-,57-,58-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human Melanocortin 3 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131880
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Cys]-Pro-Pro-Ly...)
Show SMILES CC(=O)C1C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NC(CSSC1(C)C)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H100N18O16S2/c1-41(93)64-71(107)86-51(23-24-62(97)98)67(103)89-55(32-46-35-79-40-84-46)70(106)87-53(30-42-21-22-43-13-4-5-14-44(43)29-42)68(104)85-50(18-10-26-80-73(77)78)66(102)88-54(31-45-34-81-48-16-7-6-15-47(45)48)69(105)90-56(39-109-110-74(64,2)3)72(108)92-28-12-20-58(92)61(96)38-91-27-11-19-57(91)60(95)37-82-49(17-8-9-25-75)59(94)36-83-52(65(76)101)33-63(99)100/h4-7,13-16,21-22,29,34-35,40,49-58,64,81-83H,8-12,17-20,23-28,30-33,36-39,75H2,1-3H3,(H2,76,101)(H,79,84)(H,85,104)(H,86,107)(H,87,106)(H,88,102)(H,89,103)(H,90,105)(H,97,98)(H,99,100)(H4,77,78,80)/t49-,50-,51+,52-,53-,54+,55-,56?,57-,58-,64?/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human Melanocortin 3 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131878
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-D-Cys]-Pro-Pro-...)
Show SMILES CC(=O)C1CSSCC(NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47?,49-,50-,51+,52-,53-,54+,55-,56?,57-,58-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131872
PNG
(Ac-c[Asp-Glu-His-D-Phe-Arg-Trp-Lys]-Pro-Pro-Lys-As...)
Show SMILES CC(=O)[C@@H]1CC(=O)NCCCC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H101N19O17/c1-41(92)46-33-61(96)78-26-10-8-19-51(71(108)91-29-13-22-57(91)60(95)39-90-28-12-21-56(90)59(94)38-81-48(18-7-9-25-73)58(93)37-82-52(64(74)101)34-63(99)100)86-69(106)54(31-43-35-80-47-17-6-5-16-45(43)47)88-66(103)49(20-11-27-79-72(75)76)85-68(105)53(30-42-14-3-2-4-15-42)87-70(107)55(32-44-36-77-40-83-44)89-67(104)50(84-65(46)102)23-24-62(97)98/h2-6,14-17,35-36,40,46,48-57,80-82H,7-13,18-34,37-39,73H2,1H3,(H2,74,101)(H,77,83)(H,78,96)(H,84,102)(H,85,105)(H,86,106)(H,87,107)(H,88,103)(H,89,104)(H,97,98)(H,99,100)(H4,75,76,79)/t46-,48-,49-,50+,51+,52-,53-,54+,55-,56-,57-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human Melanocortin 3 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50001519
PNG
(CHEMBL2111808)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45-,46-,47+,48-,49-,50+,51-,52-,53-,54-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131875
PNG
(Ac-c[Pen-Glu-His-D-Phe-Arg-Trp-Cys]-Pro-Pro-Lys-As...)
Show SMILES CC(=O)C1C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NC(CSSC1(C)C)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C70H98N18O16S2/c1-39(89)60-67(103)82-47(22-23-58(93)94)63(99)85-51(30-42-33-75-38-80-42)66(102)83-49(28-40-14-5-4-6-15-40)64(100)81-46(19-11-25-76-69(73)74)62(98)84-50(29-41-32-77-44-17-8-7-16-43(41)44)65(101)86-52(37-105-106-70(60,2)3)68(104)88-27-13-21-54(88)57(92)36-87-26-12-20-53(87)56(91)35-78-45(18-9-10-24-71)55(90)34-79-48(61(72)97)31-59(95)96/h4-8,14-17,32-33,38,45-54,60,77-79H,9-13,18-31,34-37,71H2,1-3H3,(H2,72,97)(H,75,80)(H,81,100)(H,82,103)(H,83,102)(H,84,98)(H,85,99)(H,86,101)(H,93,94)(H,95,96)(H4,73,74,76)/t45-,46-,47+,48-,49-,50+,51-,52?,53-,54-,60?/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 430n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human Melanocortin 3 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50001520
PNG
(CHEMBL2111807)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49-,50-,51+,52-,53-,54+,55-,56-,57-,58-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50001519
PNG
(CHEMBL2111808)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45-,46-,47+,48-,49-,50+,51-,52-,53-,54-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.60E+3n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human Melanocortin 3 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50131880
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Cys]-Pro-Pro-Ly...)
Show SMILES CC(=O)C1C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NC(CSSC1(C)C)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H100N18O16S2/c1-41(93)64-71(107)86-51(23-24-62(97)98)67(103)89-55(32-46-35-79-40-84-46)70(106)87-53(30-42-21-22-43-13-4-5-14-44(43)29-42)68(104)85-50(18-10-26-80-73(77)78)66(102)88-54(31-45-34-81-48-16-7-6-15-47(45)48)69(105)90-56(39-109-110-74(64,2)3)72(108)92-28-12-20-58(92)61(96)38-91-27-11-19-57(91)60(95)37-82-49(17-8-9-25-75)59(94)36-83-52(65(76)101)33-63(99)100/h4-7,13-16,21-22,29,34-35,40,49-58,64,81-83H,8-12,17-20,23-28,30-33,36-39,75H2,1-3H3,(H2,76,101)(H,79,84)(H,85,104)(H,86,107)(H,87,106)(H,88,102)(H,89,103)(H,90,105)(H,97,98)(H,99,100)(H4,77,78,80)/t49-,50-,51+,52-,53-,54+,55-,56?,57-,58-,64?/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131878
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-D-Cys]-Pro-Pro-...)
Show SMILES CC(=O)C1CSSCC(NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47?,49-,50-,51+,52-,53-,54+,55-,56?,57-,58-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human Melanocortin 3 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50001520
PNG
(CHEMBL2111807)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H96N18O16S2/c1-40(91)47-37-107-108-38-56(71(106)90-26-10-18-58(90)61(94)36-89-25-9-17-57(89)60(93)35-80-49(15-6-7-23-73)59(92)34-81-52(64(74)99)31-63(97)98)88-69(104)54(29-44-32-79-48-14-5-4-13-46(44)48)86-66(101)50(16-8-24-78-72(75)76)84-68(103)53(28-41-19-20-42-11-2-3-12-43(42)27-41)85-70(105)55(30-45-33-77-39-82-45)87-67(102)51(83-65(47)100)21-22-62(95)96/h2-5,11-14,19-20,27,32-33,39,47,49-58,79-81H,6-10,15-18,21-26,28-31,34-38,73H2,1H3,(H2,74,99)(H,77,82)(H,83,100)(H,84,103)(H,85,105)(H,86,101)(H,87,102)(H,88,104)(H,95,96)(H,97,98)(H4,75,76,78)/t47-,49-,50-,51+,52-,53-,54+,55-,56-,57-,58-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 180n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 5 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50001519
PNG
(CHEMBL2111808)
Show SMILES CC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45-,46-,47+,48-,49-,50+,51-,52-,53-,54-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human melanocortin 5 receptor


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131880
PNG
(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Cys]-Pro-Pro-Ly...)
Show SMILES CC(=O)C1C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NC(CSSC1(C)C)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C74H100N18O16S2/c1-41(93)64-71(107)86-51(23-24-62(97)98)67(103)89-55(32-46-35-79-40-84-46)70(106)87-53(30-42-21-22-43-13-4-5-14-44(43)29-42)68(104)85-50(18-10-26-80-73(77)78)66(102)88-54(31-45-34-81-48-16-7-6-15-47(45)48)69(105)90-56(39-109-110-74(64,2)3)72(108)92-28-12-20-58(92)61(96)38-91-27-11-19-57(91)60(95)37-82-49(17-8-9-25-75)59(94)36-83-52(65(76)101)33-63(99)100/h4-7,13-16,21-22,29,34-35,40,49-58,64,81-83H,8-12,17-20,23-28,30-33,36-39,75H2,1-3H3,(H2,76,101)(H,79,84)(H,85,104)(H,86,107)(H,87,106)(H,88,102)(H,89,103)(H,90,105)(H,97,98)(H,99,100)(H4,77,78,80)/t49-,50-,51+,52-,53-,54+,55-,56?,57-,58-,64?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50001505
PNG
(CHEMBL2112604)
Show SMILES CC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C68H94N18O16S2/c1-38(87)43-35-103-104-36-52(67(102)86-25-11-19-54(86)57(90)34-85-24-10-18-53(85)56(89)33-76-45(16-7-8-22-69)55(88)32-77-48(60(70)95)29-59(93)94)84-65(100)50(27-40-30-75-44-15-6-5-14-42(40)44)82-62(97)46(17-9-23-74-68(71)72)80-64(99)49(26-39-12-3-2-4-13-39)81-66(101)51(28-41-31-73-37-78-41)83-63(98)47(79-61(43)96)20-21-58(91)92/h2-6,12-15,30-31,37,43,45-54,75-77H,7-11,16-29,32-36,69H2,1H3,(H2,70,95)(H,73,78)(H,79,96)(H,80,99)(H,81,101)(H,82,97)(H,83,98)(H,84,100)(H,91,92)(H,93,94)(H4,71,72,74)/t43-,45+,46+,47-,48+,49+,50-,51+,52-,53+,54+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50131875
PNG
(Ac-c[Pen-Glu-His-D-Phe-Arg-Trp-Cys]-Pro-Pro-Lys-As...)
Show SMILES CC(=O)C1C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NC(CSSC1(C)C)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C70H98N18O16S2/c1-39(89)60-67(103)82-47(22-23-58(93)94)63(99)85-51(30-42-33-75-38-80-42)66(102)83-49(28-40-14-5-4-6-15-40)64(100)81-46(19-11-25-76-69(73)74)62(98)84-50(29-41-32-77-44-17-8-7-16-43(41)44)65(101)86-52(37-105-106-70(60,2)3)68(104)88-27-13-21-54(88)57(92)36-87-26-12-20-53(87)56(91)35-78-45(18-9-10-24-71)55(90)34-79-48(61(72)97)31-59(95)96/h4-8,14-17,32-33,38,45-54,60,77-79H,9-13,18-31,34-37,71H2,1-3H3,(H2,72,97)(H,75,80)(H,81,100)(H,82,103)(H,83,102)(H,84,98)(H,85,99)(H,86,101)(H,93,94)(H,95,96)(H4,73,74,76)/t45-,46-,47+,48-,49-,50+,51-,52?,53-,54-,60?/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50131872
PNG
(Ac-c[Asp-Glu-His-D-Phe-Arg-Trp-Lys]-Pro-Pro-Lys-As...)
Show SMILES CC(=O)[C@@H]1CC(=O)NCCCC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H101N19O17/c1-41(92)46-33-61(96)78-26-10-8-19-51(71(108)91-29-13-22-57(91)60(95)39-90-28-12-21-56(90)59(94)38-81-48(18-7-9-25-73)58(93)37-82-52(64(74)101)34-63(99)100)86-69(106)54(31-43-35-80-47-17-6-5-16-45(43)47)88-66(103)49(20-11-27-79-72(75)76)85-68(105)53(30-42-14-3-2-4-15-42)87-70(107)55(32-44-36-77-40-83-44)89-67(104)50(84-65(46)102)23-24-62(97)98/h2-6,14-17,35-36,40,46,48-57,80-82H,7-13,18-34,37-39,73H2,1H3,(H2,74,101)(H,77,83)(H,78,96)(H,84,102)(H,85,105)(H,86,106)(H,87,107)(H,88,103)(H,89,104)(H,97,98)(H,99,100)(H4,75,76,79)/t46-,48-,49-,50+,51+,52-,53-,54+,55-,56-,57-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131875
PNG
(Ac-c[Pen-Glu-His-D-Phe-Arg-Trp-Cys]-Pro-Pro-Lys-As...)
Show SMILES CC(=O)C1C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NC(CSSC1(C)C)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C70H98N18O16S2/c1-39(89)60-67(103)82-47(22-23-58(93)94)63(99)85-51(30-42-33-75-38-80-42)66(102)83-49(28-40-14-5-4-6-15-40)64(100)81-46(19-11-25-76-69(73)74)62(98)84-50(29-41-32-77-44-17-8-7-16-43(41)44)65(101)86-52(37-105-106-70(60,2)3)68(104)88-27-13-21-54(88)57(92)36-87-26-12-20-53(87)56(91)35-78-45(18-9-10-24-71)55(90)34-79-48(61(72)97)31-59(95)96/h4-8,14-17,32-33,38,45-54,60,77-79H,9-13,18-31,34-37,71H2,1-3H3,(H2,72,97)(H,75,80)(H,81,100)(H,82,103)(H,83,102)(H,84,98)(H,85,99)(H,86,101)(H,93,94)(H,95,96)(H4,73,74,76)/t45-,46-,47+,48-,49-,50+,51-,52?,53-,54-,60?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.30n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131872
PNG
(Ac-c[Asp-Glu-His-D-Phe-Arg-Trp-Lys]-Pro-Pro-Lys-As...)
Show SMILES CC(=O)[C@@H]1CC(=O)NCCCC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)CN1CCC[C@H]1C(=O)CN[C@@H](CCCCN)C(=O)CN[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C72H101N19O17/c1-41(92)46-33-61(96)78-26-10-8-19-51(71(108)91-29-13-22-57(91)60(95)39-90-28-12-21-56(90)59(94)38-81-48(18-7-9-25-73)58(93)37-82-52(64(74)101)34-63(99)100)86-69(106)54(31-43-35-80-47-17-6-5-16-45(43)47)88-66(103)49(20-11-27-79-72(75)76)85-68(105)53(30-42-14-3-2-4-15-42)87-70(107)55(32-44-36-77-40-83-44)89-67(104)50(84-65(46)102)23-24-62(97)98/h2-6,14-17,35-36,40,46,48-57,80-82H,7-13,18-34,37-39,73H2,1H3,(H2,74,101)(H,77,83)(H,78,96)(H,84,102)(H,85,105)(H,86,106)(H,87,107)(H,88,103)(H,89,104)(H,97,98)(H,99,100)(H4,75,76,79)/t46-,48-,49-,50+,51+,52-,53-,54+,55-,56-,57-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Effective concentration of peptide at 50% maximal cAMP generation


J Med Chem 46: 3728-33 (2003)


Article DOI: 10.1021/jm030111j
BindingDB Entry DOI: 10.7270/Q2125TDT
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50105883
PNG
(3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-prop...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(N)=O
Show InChI InChI=1S/C51H63N15O11S2/c1-27(67)60-41-25-79-78-24-40(44(52)71)61-42(68)23-58-45(72)38(19-31-21-57-34-10-5-4-9-33(31)34)65-46(73)35(11-6-16-56-51(53)54)62-48(75)37(18-28-12-13-29-7-2-3-8-30(29)17-28)64-49(76)39(20-32-22-55-26-59-32)66-47(74)36(63-50(41)77)14-15-43(69)70/h2-5,7-10,12-13,17,21-22,26,35-41,57H,6,11,14-16,18-20,23-25H2,1H3,(H2,52,71)(H,55,59)(H,58,72)(H,60,67)(H,61,68)(H,62,75)(H,63,77)(H,64,76)(H,65,73)(H,66,74)(H,69,70)(H4,53,54,56)/t35-,36+,37-,38+,39-,40-,41+/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.220n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Increase in intracellular cAMP in CHO cells expressing human melanocortin receptor 5.


J Med Chem 44: 3665-72 (2001)


Article DOI: 10.1021/jm010165y
BindingDB Entry DOI: 10.7270/Q2RF5T9S
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 67 total )  |  Next  |  Last  >>