BindingDB logo
myBDB logout

16 similar compounds to monomer 160201

Compile data set for download or QSAR
Wt: 823.0
BDBM84641
Wt: 794.9
BDBM84642
Wt: 794.9
BDBM84644
Wt: 1106.3
BDBM50405764
Wt: 1120.3
BDBM50405766
Wt: 1121.2
BDBM135629
Wt: 1065.2
BDBM135749
Wt: 1079.6
BDBM160203
Wt: 1079.6
BDBM160209
Wt: 1155.7
BDBM160217
Wt: 1092.6
BDBM160266
Wt: 1051.5
BDBM160185
Wt: 1065.6
BDBM160186
Wt: 1092.6
BDBM160188
Wt: 1051.5
BDBM160189
Displayed 1 to 15 (of 16 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 84641,84642,84644,50405764,50405766,135629,135749,160203,160209,160217,160266,160185,160186,160188,160189   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160217
PNG
(US9040663, 63)
Show SMILES C[C@@H](OCc1ccccc1)[C@@H]1NC(=O)[C@H](CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C55H75ClN16O10/c1-31(82-30-33-13-4-3-5-14-33)46-53(81)71-43(27-34-15-6-8-17-37(34)56)52(80)68-41(21-12-26-64-55(60)61)49(77)70-44(28-35-29-65-38-18-9-7-16-36(35)38)51(79)67-39(47(57)75)19-10-24-62-45(74)23-22-42(50(78)72-46)69-48(76)40(66-32(2)73)20-11-25-63-54(58)59/h3-9,13-18,29,31,39-44,46,65H,10-12,19-28,30H2,1-2H3,(H2,57,75)(H,62,74)(H,66,73)(H,67,79)(H,68,80)(H,69,76)(H,70,77)(H,71,81)(H,72,78)(H4,58,59,63)(H4,60,61,64)/t31-,39+,40+,41+,42+,43-,44+,46+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
0.350 -13.4n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM135629
PNG
(US10179804, Example 14 | US8846601, 14 | US9458201...)
Show SMILES C[C@@H](OCc1ccccc1)[C@@H]1NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C55H76N16O10/c1-32(81-31-35-17-7-4-8-18-35)46-53(80)70-42(27-34-15-5-3-6-16-34)50(77)67-41(23-14-26-63-55(59)60)49(76)68-43(28-36-30-64-38-20-10-9-19-37(36)38)51(78)66-39(47(56)74)21-11-12-24-61-45(73)29-44(52(79)71-46)69-48(75)40(65-33(2)72)22-13-25-62-54(57)58/h3-10,15-20,30,32,39-44,46,64H,11-14,21-29,31H2,1-2H3,(H2,56,74)(H,61,73)(H,65,72)(H,66,78)(H,67,77)(H,68,76)(H,69,75)(H,70,80)(H,71,79)(H4,57,58,62)(H4,59,60,63)/t32-,39+,40+,41+,42-,43+,44+,46+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
1n/an/an/an/an/an/a7.5n/a



Palatin Technologies, Inc.

US Patent


Assay Description
A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...


US Patent US8846601 (2014)


BindingDB Entry DOI: 10.7270/Q2SF2TWK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM135629
PNG
(US10179804, Example 14 | US8846601, 14 | US9458201...)
Show SMILES C[C@@H](OCc1ccccc1)[C@@H]1NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C55H76N16O10/c1-32(81-31-35-17-7-4-8-18-35)46-53(80)70-42(27-34-15-5-3-6-16-34)50(77)67-41(23-14-26-63-55(59)60)49(76)68-43(28-36-30-64-38-20-10-9-19-37(36)38)51(78)66-39(47(56)74)21-11-12-24-61-45(73)29-44(52(79)71-46)69-48(75)40(65-33(2)72)22-13-25-62-54(57)58/h3-10,15-20,30,32,39-44,46,64H,11-14,21-29,31H2,1-2H3,(H2,56,74)(H,61,73)(H,65,72)(H,66,78)(H,67,77)(H,68,76)(H,69,75)(H,70,80)(H,71,79)(H4,57,58,62)(H4,59,60,63)/t32-,39+,40+,41+,42-,43+,44+,46+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
1n/an/an/an/an/an/an/an/a



Palatin Technologies, Inc.

US Patent


Assay Description
Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...


US Patent US10179804 (2019)

More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM135629
PNG
(US10179804, Example 14 | US8846601, 14 | US9458201...)
Show SMILES C[C@@H](OCc1ccccc1)[C@@H]1NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C55H76N16O10/c1-32(81-31-35-17-7-4-8-18-35)46-53(80)70-42(27-34-15-5-3-6-16-34)50(77)67-41(23-14-26-63-55(59)60)49(76)68-43(28-36-30-64-38-20-10-9-19-37(36)38)51(78)66-39(47(56)74)21-11-12-24-61-45(73)29-44(52(79)71-46)69-48(75)40(65-33(2)72)22-13-25-62-54(57)58/h3-10,15-20,30,32,39-44,46,64H,11-14,21-29,31H2,1-2H3,(H2,56,74)(H,61,73)(H,65,72)(H,66,78)(H,67,77)(H,68,76)(H,69,75)(H,70,80)(H,71,79)(H4,57,58,62)(H4,59,60,63)/t32-,39+,40+,41+,42-,43+,44+,46+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
1 -12.8n/an/an/an/an/a7.537



Palatin Technologies, Inc.

US Patent


Assay Description
A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...


US Patent US9458201 (2016)


BindingDB Entry DOI: 10.7270/Q2HT2N79
More data for this
Ligand-Target Pair
Luteinizing hormone/Choriogonadotropin receptor


(Rattus norvegicus)
BDBM50405764
PNG
(CHEMBL264298)
Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)Cc1cccc2ccccc12
Show InChI InChI=1S/C61H75N11O9/c1-4-64-59(79)53-24-14-30-72(53)60(80)48(23-13-29-65-61(62)63)68-55(75)49(31-38(2)3)69-57(77)51(33-43-35-66-47-22-11-10-21-46(43)47)71-56(76)50(32-39-25-27-44(73)28-26-39)70-58(78)52(37-81-36-40-15-6-5-7-16-40)67-54(74)34-42-19-12-18-41-17-8-9-20-45(41)42/h5-12,15-22,25-28,35,38,48-53,66,73H,4,13-14,23-24,29-34,36-37H2,1-3H3,(H,64,79)(H,67,74)(H,68,75)(H,69,77)(H,70,78)(H,71,76)(H4,62,63,65)/t48-,49-,50-,51+,52-,53?/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.20n/an/an/an/an/an/an/an/a



Abbott Laboratory

Curated by ChEMBL


Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib...


J Med Chem 32: 2340-4 (1989)


Article DOI: 10.1021/jm00130a019
BindingDB Entry DOI: 10.7270/Q2H70H1B
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160266
PNG
(US9040663, 112)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCCNC(=O)CC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O
Show InChI InChI=1S/C49H70ClN17O10/c1-26(68)61-33(13-7-21-58-48(53)54)42(72)63-34-14-6-20-57-40(70)19-17-32(41(52)71)62-46(76)38(24-28-25-60-31-12-5-3-10-29(28)31)67-44(74)35(15-8-22-59-49(55)56)64-47(77)37(23-27-9-2-4-11-30(27)50)66-45(75)36(65-43(34)73)16-18-39(51)69/h2-5,9-12,25,32-38,60H,6-8,13-24H2,1H3,(H2,51,69)(H2,52,71)(H,57,70)(H,61,68)(H,62,76)(H,63,72)(H,64,77)(H,65,73)(H,66,75)(H,67,74)(H4,53,54,58)(H4,55,56,59)/t32-,33-,34-,35-,36-,37+,38-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
4 -11.9n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Luteinizing hormone/Choriogonadotropin receptor


(Rattus norvegicus)
BDBM50405766
PNG
(CHEMBL386525)
Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)CCc1cccc2ccccc12
Show InChI InChI=1S/C62H77N11O9/c1-4-65-60(80)54-24-14-32-73(54)61(81)49(23-13-31-66-62(63)64)69-56(76)50(33-39(2)3)70-58(78)52(35-44-36-67-48-22-11-10-21-47(44)48)72-57(77)51(34-40-25-28-45(74)29-26-40)71-59(79)53(38-82-37-41-15-6-5-7-16-41)68-55(75)30-27-43-19-12-18-42-17-8-9-20-46(42)43/h5-12,15-22,25-26,28-29,36,39,49-54,67,74H,4,13-14,23-24,27,30-35,37-38H2,1-3H3,(H,65,80)(H,68,75)(H,69,76)(H,70,78)(H,71,79)(H,72,77)(H4,63,64,66)/t49-,50-,51-,52+,53-,54?/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.30n/an/an/an/an/an/an/an/a



Abbott Laboratory

Curated by ChEMBL


Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib...


J Med Chem 32: 2340-4 (1989)


Article DOI: 10.1021/jm00130a019
BindingDB Entry DOI: 10.7270/Q2H70H1B
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160188
PNG
(US9040663, 34)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O
Show InChI InChI=1S/C49H70ClN17O10/c1-26(68)61-33(14-7-21-58-48(53)54)42(72)65-36-17-19-40(70)57-20-6-13-32(41(52)71)62-46(76)38(24-28-25-60-31-12-5-3-10-29(28)31)67-43(73)34(15-8-22-59-49(55)56)63-47(77)37(23-27-9-2-4-11-30(27)50)66-45(75)35(64-44(36)74)16-18-39(51)69/h2-5,9-12,25,32-38,60H,6-8,13-24H2,1H3,(H2,51,69)(H2,52,71)(H,57,70)(H,61,68)(H,62,76)(H,63,77)(H,64,74)(H,65,72)(H,66,75)(H,67,73)(H4,53,54,58)(H4,55,56,59)/t32-,33-,34-,35-,36-,37+,38-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
7 -11.6n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160185
PNG
(US9040663, 31)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC(=O)[C@H](CO)NC1=O)C(N)=O
Show InChI InChI=1S/C47H67ClN16O10/c1-25(66)58-32(14-7-19-55-46(50)51)40(69)61-34-16-17-38(67)54-18-6-13-31(39(49)68)59-43(72)36(22-27-23-57-30-12-5-3-10-28(27)30)62-41(70)33(15-8-20-56-47(52)53)60-44(73)35(21-26-9-2-4-11-29(26)48)63-45(74)37(24-65)64-42(34)71/h2-5,9-12,23,31-37,57,65H,6-8,13-22,24H2,1H3,(H2,49,68)(H,54,67)(H,58,66)(H,59,72)(H,60,73)(H,61,69)(H,62,70)(H,63,74)(H,64,71)(H4,50,51,55)(H4,52,53,56)/t31-,32-,33-,34-,35+,36-,37-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
8 -11.5n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM160203
PNG
(US9040663, 49)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC(=O)[C@H](CCCN)NC1=O)C(O)=O
Show InChI InChI=1S/C49H71ClN16O10/c1-27(67)60-33(15-7-22-57-48(52)53)41(69)63-36-18-19-40(68)56-21-9-17-37(47(75)76)64-46(74)39(25-29-26-59-32-13-5-3-11-30(29)32)66-43(71)35(16-8-23-58-49(54)55)62-45(73)38(24-28-10-2-4-12-31(28)50)65-42(70)34(14-6-20-51)61-44(36)72/h2-5,10-13,26,33-39,59H,6-9,14-25,51H2,1H3,(H,56,68)(H,60,67)(H,61,72)(H,62,73)(H,63,69)(H,64,74)(H,65,70)(H,66,71)(H,75,76)(H4,52,53,57)(H4,54,55,58)/t33-,34-,35-,36-,37-,38+,39-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
8 -11.5n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160203
PNG
(US9040663, 49)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC(=O)[C@H](CCCN)NC1=O)C(O)=O
Show InChI InChI=1S/C49H71ClN16O10/c1-27(67)60-33(15-7-22-57-48(52)53)41(69)63-36-18-19-40(68)56-21-9-17-37(47(75)76)64-46(74)39(25-29-26-59-32-13-5-3-11-30(29)32)66-43(71)35(16-8-23-58-49(54)55)62-45(73)38(24-28-10-2-4-12-31(28)50)65-42(70)34(14-6-20-51)61-44(36)72/h2-5,10-13,26,33-39,59H,6-9,14-25,51H2,1H3,(H,56,68)(H,60,67)(H,61,72)(H,62,73)(H,63,69)(H,64,74)(H,65,70)(H,66,71)(H,75,76)(H4,52,53,57)(H4,54,55,58)/t33-,34-,35-,36-,37-,38+,39-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
8 -11.5n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160189
PNG
(US9040663, 35)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc(Cl)c2)NC(=O)[C@H](CO)NC1=O)C(N)=O
Show InChI InChI=1S/C47H67ClN16O10/c1-25(66)58-32(13-6-18-55-46(50)51)40(69)61-34-15-16-38(67)54-17-5-12-31(39(49)68)59-44(73)36(22-27-23-57-30-11-3-2-10-29(27)30)63-41(70)33(14-7-19-56-47(52)53)60-43(72)35(21-26-8-4-9-28(48)20-26)62-45(74)37(24-65)64-42(34)71/h2-4,8-11,20,23,31-37,57,65H,5-7,12-19,21-22,24H2,1H3,(H2,49,68)(H,54,67)(H,58,66)(H,59,73)(H,60,72)(H,61,69)(H,62,74)(H,63,70)(H,64,71)(H4,50,51,55)(H4,52,53,56)/t31-,32-,33-,34-,35+,36-,37-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
10 -11.3n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160186
PNG
(US9040663, 32)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C48H69ClN16O10/c1-25(66)39-46(75)64-36(22-27-10-3-5-12-30(27)49)45(74)61-34(16-9-21-57-48(53)54)42(71)63-37(23-28-24-58-31-13-6-4-11-29(28)31)44(73)60-32(40(50)69)14-7-19-55-38(68)18-17-35(43(72)65-39)62-41(70)33(59-26(2)67)15-8-20-56-47(51)52/h3-6,10-13,24-25,32-37,39,58,66H,7-9,14-23H2,1-2H3,(H2,50,69)(H,55,68)(H,59,67)(H,60,73)(H,61,74)(H,62,70)(H,63,71)(H,64,75)(H,65,72)(H4,51,52,56)(H4,53,54,57)/t25-,32+,33+,34+,35+,36-,37+,39+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
11 -11.3n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM160217
PNG
(US9040663, 63)
Show SMILES C[C@@H](OCc1ccccc1)[C@@H]1NC(=O)[C@H](CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C55H75ClN16O10/c1-31(82-30-33-13-4-3-5-14-33)46-53(81)71-43(27-34-15-6-8-17-37(34)56)52(80)68-41(21-12-26-64-55(60)61)49(77)70-44(28-35-29-65-38-18-9-7-16-36(35)38)51(79)67-39(47(57)75)19-10-24-62-45(74)23-22-42(50(78)72-46)69-48(76)40(66-32(2)73)20-11-25-63-54(58)59/h3-9,13-18,29,31,39-44,46,65H,10-12,19-28,30H2,1-2H3,(H2,57,75)(H,62,74)(H,66,73)(H,67,79)(H,68,80)(H,69,76)(H,70,77)(H,71,81)(H,72,78)(H4,58,59,63)(H4,60,61,64)/t31-,39+,40+,41+,42+,43-,44+,46+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
12 -11.2n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160209
PNG
(US9040663, 55)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc(Cl)c2)NC(=O)[C@H](CCCN)NC1=O)C(O)=O
Show InChI InChI=1S/C49H71ClN16O10/c1-27(67)60-33(14-6-21-57-48(52)53)41(69)63-36-17-18-40(68)56-20-8-16-37(47(75)76)64-46(74)39(25-29-26-59-32-12-3-2-11-31(29)32)66-43(71)35(15-7-22-58-49(54)55)62-45(73)38(24-28-9-4-10-30(50)23-28)65-42(70)34(13-5-19-51)61-44(36)72/h2-4,9-12,23,26,33-39,59H,5-8,13-22,24-25,51H2,1H3,(H,56,68)(H,60,67)(H,61,72)(H,62,73)(H,63,69)(H,64,74)(H,65,70)(H,66,71)(H,75,76)(H4,52,53,57)(H4,54,55,58)/t33-,34-,35-,36-,37-,38+,39-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
20 -10.9n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM160209
PNG
(US9040663, 55)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc(Cl)c2)NC(=O)[C@H](CCCN)NC1=O)C(O)=O
Show InChI InChI=1S/C49H71ClN16O10/c1-27(67)60-33(14-6-21-57-48(52)53)41(69)63-36-17-18-40(68)56-20-8-16-37(47(75)76)64-46(74)39(25-29-26-59-32-12-3-2-11-31(29)32)66-43(71)35(15-7-22-58-49(54)55)62-45(73)38(24-28-9-4-10-30(50)23-28)65-42(70)34(13-5-19-51)61-44(36)72/h2-4,9-12,23,26,33-39,59H,5-8,13-22,24-25,51H2,1H3,(H,56,68)(H,60,67)(H,61,72)(H,62,73)(H,63,69)(H,64,74)(H,65,70)(H,66,71)(H,75,76)(H4,52,53,57)(H4,54,55,58)/t33-,34-,35-,36-,37-,38+,39-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
23 -10.8n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM135749
PNG
(US8846601, 134)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](COCc2ccccc2)NC1=O)C(N)=O
Show InChI InChI=1S/C52H72N16O9/c53-35(18-11-23-60-51(55)56)45(71)65-41-27-43(69)59-22-10-9-20-37(44(54)70)63-48(74)40(26-33-28-62-36-19-8-7-17-34(33)36)67-46(72)38(21-12-24-61-52(57)58)64-47(73)39(25-31-13-3-1-4-14-31)66-50(76)42(68-49(41)75)30-77-29-32-15-5-2-6-16-32/h1-8,13-17,19,28,35,37-42,62H,9-12,18,20-27,29-30,53H2,(H2,54,70)(H,59,69)(H,63,74)(H,64,73)(H,65,71)(H,66,76)(H,67,72)(H,68,75)(H4,55,56,60)(H4,57,58,61)/t35-,37-,38-,39+,40-,41-,42-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
30n/an/an/an/an/an/a7.5n/a



Palatin Technologies, Inc.

US Patent


Assay Description
A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...


US Patent US8846601 (2014)


BindingDB Entry DOI: 10.7270/Q2SF2TWK
More data for this
Ligand-Target Pair
SSTR4


(RAT)
BDBM84642
PNG
(SA IV | c[Ahx-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C44H58N8O6/c1-29(58-28-31-17-8-5-9-18-31)39-44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(25-30-15-6-4-7-16-30)42(55)48-35(41(54)52-39)21-10-2-3-13-23-45/h4-9,11-12,15-20,27,29,35-39,47H,2-3,10,13-14,21-26,28,45-46H2,1H3,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
34n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 44: 385-92 (1993)


BindingDB Entry DOI: 10.7270/Q2X065KZ
More data for this
Ligand-Target Pair
SSTR4


(RAT)
BDBM84641
PNG
(SA V | c[Aoc-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C46H62N8O6/c1-31(60-30-33-19-10-7-11-20-33)41-46(59)51-38(24-16-26-48)42(55)53-40(28-34-29-49-36-22-14-13-21-35(34)36)45(58)52-39(27-32-17-8-6-9-18-32)44(57)50-37(43(56)54-41)23-12-4-2-3-5-15-25-47/h6-11,13-14,17-22,29,31,37-41,49H,2-5,12,15-16,23-28,30,47-48H2,1H3,(H,50,57)(H,51,59)(H,52,58)(H,53,55)(H,54,56)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
50n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 44: 385-92 (1993)


BindingDB Entry DOI: 10.7270/Q2X065KZ
More data for this
Ligand-Target Pair
SSTR3


(MOUSE)
BDBM84642
PNG
(SA IV | c[Ahx-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C44H58N8O6/c1-29(58-28-31-17-8-5-9-18-31)39-44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(25-30-15-6-4-7-16-30)42(55)48-35(41(54)52-39)21-10-2-3-13-23-45/h4-9,11-12,15-20,27,29,35-39,47H,2-3,10,13-14,21-26,28,45-46H2,1H3,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
73n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM84644
PNG
(III | SA III | c[Aha-Phe-D-Trp-Lys-Ser(Bzl)])
Show SMILES NCCCCCCCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC(=O)C(COCc2ccccc2)NC1=O
Show InChI InChI=1S/C44H58N8O6/c45-23-13-3-1-2-10-21-35-41(54)52-39(29-58-28-31-17-8-5-9-18-31)44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(42(55)48-35)25-30-15-6-4-7-16-30/h4-9,11-12,15-20,27,35-39,47H,1-3,10,13-14,21-26,28-29,45-46H2,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
80n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM160266
PNG
(US9040663, 112)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCCNC(=O)CC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O
Show InChI InChI=1S/C49H70ClN17O10/c1-26(68)61-33(13-7-21-58-48(53)54)42(72)63-34-14-6-20-57-40(70)19-17-32(41(52)71)62-46(76)38(24-28-25-60-31-12-5-3-10-29(28)31)67-44(74)35(15-8-22-59-49(55)56)64-47(77)37(23-27-9-2-4-11-30(27)50)66-45(75)36(65-43(34)73)16-18-39(51)69/h2-5,9-12,25,32-38,60H,6-8,13-24H2,1H3,(H2,51,69)(H2,52,71)(H,57,70)(H,61,68)(H,62,76)(H,63,72)(H,64,77)(H,65,73)(H,66,75)(H,67,74)(H4,53,54,58)(H4,55,56,59)/t32-,33-,34-,35-,36-,37+,38-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
83 -10.0n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
SSTR3


(MOUSE)
BDBM84641
PNG
(SA V | c[Aoc-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C46H62N8O6/c1-31(60-30-33-19-10-7-11-20-33)41-46(59)51-38(24-16-26-48)42(55)53-40(28-34-29-49-36-22-14-13-21-35(34)36)45(58)52-39(27-32-17-8-6-9-18-32)44(57)50-37(43(56)54-41)23-12-4-2-3-5-15-25-47/h6-11,13-14,17-22,29,31,37-41,49H,2-5,12,15-16,23-28,30,47-48H2,1H3,(H,50,57)(H,51,59)(H,52,58)(H,53,55)(H,54,56)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
101n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM160188
PNG
(US9040663, 34)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O
Show InChI InChI=1S/C49H70ClN17O10/c1-26(68)61-33(14-7-21-58-48(53)54)42(72)65-36-17-19-40(70)57-20-6-13-32(41(52)71)62-46(76)38(24-28-25-60-31-12-5-3-10-29(28)31)67-43(73)34(15-8-22-59-49(55)56)63-47(77)37(23-27-9-2-4-11-30(27)50)66-45(75)35(64-44(36)74)16-18-39(51)69/h2-5,9-12,25,32-38,60H,6-8,13-24H2,1H3,(H2,51,69)(H2,52,71)(H,57,70)(H,61,68)(H,62,76)(H,63,77)(H,64,74)(H,65,72)(H,66,75)(H,67,73)(H4,53,54,58)(H4,55,56,59)/t32-,33-,34-,35-,36-,37+,38-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
128 -9.77n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM84642
PNG
(SA IV | c[Ahx-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C44H58N8O6/c1-29(58-28-31-17-8-5-9-18-31)39-44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(25-30-15-6-4-7-16-30)42(55)48-35(41(54)52-39)21-10-2-3-13-23-45/h4-9,11-12,15-20,27,29,35-39,47H,2-3,10,13-14,21-26,28,45-46H2,1H3,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
183n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
SSTR4


(RAT)
BDBM84644
PNG
(III | SA III | c[Aha-Phe-D-Trp-Lys-Ser(Bzl)])
Show SMILES NCCCCCCCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC(=O)C(COCc2ccccc2)NC1=O
Show InChI InChI=1S/C44H58N8O6/c45-23-13-3-1-2-10-21-35-41(54)52-39(29-58-28-31-17-8-5-9-18-31)44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(42(55)48-35)25-30-15-6-4-7-16-30/h4-9,11-12,15-20,27,35-39,47H,1-3,10,13-14,21-26,28-29,45-46H2,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
188n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 44: 385-92 (1993)


BindingDB Entry DOI: 10.7270/Q2X065KZ
More data for this
Ligand-Target Pair
SSTR3


(MOUSE)
BDBM84644
PNG
(III | SA III | c[Aha-Phe-D-Trp-Lys-Ser(Bzl)])
Show SMILES NCCCCCCCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC(=O)C(COCc2ccccc2)NC1=O
Show InChI InChI=1S/C44H58N8O6/c45-23-13-3-1-2-10-21-35-41(54)52-39(29-58-28-31-17-8-5-9-18-31)44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(42(55)48-35)25-30-15-6-4-7-16-30/h4-9,11-12,15-20,27,35-39,47H,1-3,10,13-14,21-26,28-29,45-46H2,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
214n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM160185
PNG
(US9040663, 31)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC(=O)[C@H](CO)NC1=O)C(N)=O
Show InChI InChI=1S/C47H67ClN16O10/c1-25(66)58-32(14-7-19-55-46(50)51)40(69)61-34-16-17-38(67)54-18-6-13-31(39(49)68)59-43(72)36(22-27-23-57-30-12-5-3-10-28(27)30)62-41(70)33(15-8-20-56-47(52)53)60-44(73)35(21-26-9-2-4-11-29(26)48)63-45(74)37(24-65)64-42(34)71/h2-5,9-12,23,31-37,57,65H,6-8,13-22,24H2,1H3,(H2,49,68)(H,54,67)(H,58,66)(H,59,72)(H,60,73)(H,61,69)(H,62,70)(H,63,74)(H,64,71)(H4,50,51,55)(H4,52,53,56)/t31-,32-,33-,34-,35+,36-,37-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
300 -9.25n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM160186
PNG
(US9040663, 32)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C48H69ClN16O10/c1-25(66)39-46(75)64-36(22-27-10-3-5-12-30(27)49)45(74)61-34(16-9-21-57-48(53)54)42(71)63-37(23-28-24-58-31-13-6-4-11-29(28)31)44(73)60-32(40(50)69)14-7-19-55-38(68)18-17-35(43(72)65-39)62-41(70)33(59-26(2)67)15-8-20-56-47(51)52/h3-6,10-13,24-25,32-37,39,58,66H,7-9,14-23H2,1-2H3,(H2,50,69)(H,55,68)(H,59,67)(H,60,73)(H,61,74)(H,62,70)(H,63,71)(H,64,75)(H,65,72)(H4,51,52,56)(H4,53,54,57)/t25-,32+,33+,34+,35+,36-,37+,39+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
540 -8.89n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM84641
PNG
(SA V | c[Aoc-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C46H62N8O6/c1-31(60-30-33-19-10-7-11-20-33)41-46(59)51-38(24-16-26-48)42(55)53-40(28-34-29-49-36-22-14-13-21-35(34)36)45(58)52-39(27-32-17-8-6-9-18-32)44(57)50-37(43(56)54-41)23-12-4-2-3-5-15-25-47/h6-11,13-14,17-22,29,31,37-41,49H,2-5,12,15-16,23-28,30,47-48H2,1H3,(H,50,57)(H,51,59)(H,52,58)(H,53,55)(H,54,56)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
700n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM160189
PNG
(US9040663, 35)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc(Cl)c2)NC(=O)[C@H](CO)NC1=O)C(N)=O
Show InChI InChI=1S/C47H67ClN16O10/c1-25(66)58-32(13-6-18-55-46(50)51)40(69)61-34-15-16-38(67)54-17-5-12-31(39(49)68)59-44(73)36(22-27-23-57-30-11-3-2-10-29(27)30)63-41(70)33(14-7-19-56-47(52)53)60-43(72)35(21-26-8-4-9-28(48)20-26)62-45(74)37(24-65)64-42(34)71/h2-4,8-11,20,23,31-37,57,65H,5-7,12-19,21-22,24H2,1H3,(H2,49,68)(H,54,67)(H,58,66)(H,59,73)(H,60,72)(H,61,69)(H,62,74)(H,63,70)(H,64,71)(H4,50,51,55)(H4,52,53,56)/t31-,32-,33-,34-,35+,36-,37-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
810 -8.64n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM84644
PNG
(III | SA III | c[Aha-Phe-D-Trp-Lys-Ser(Bzl)])
Show SMILES NCCCCCCCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC(=O)C(COCc2ccccc2)NC1=O
Show InChI InChI=1S/C44H58N8O6/c45-23-13-3-1-2-10-21-35-41(54)52-39(29-58-28-31-17-8-5-9-18-31)44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(42(55)48-35)25-30-15-6-4-7-16-30/h4-9,11-12,15-20,27,35-39,47H,1-3,10,13-14,21-26,28-29,45-46H2,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
1.00E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 44: 385-92 (1993)


BindingDB Entry DOI: 10.7270/Q2X065KZ
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM84641
PNG
(SA V | c[Aoc-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C46H62N8O6/c1-31(60-30-33-19-10-7-11-20-33)41-46(59)51-38(24-16-26-48)42(55)53-40(28-34-29-49-36-22-14-13-21-35(34)36)45(58)52-39(27-32-17-8-6-9-18-32)44(57)50-37(43(56)54-41)23-12-4-2-3-5-15-25-47/h6-11,13-14,17-22,29,31,37-41,49H,2-5,12,15-16,23-28,30,47-48H2,1H3,(H,50,57)(H,51,59)(H,52,58)(H,53,55)(H,54,56)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
1.00E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 44: 385-92 (1993)


BindingDB Entry DOI: 10.7270/Q2X065KZ
More data for this
Ligand-Target Pair
SSTR2


(MOUSE)
BDBM84641
PNG
(SA V | c[Aoc-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C46H62N8O6/c1-31(60-30-33-19-10-7-11-20-33)41-46(59)51-38(24-16-26-48)42(55)53-40(28-34-29-49-36-22-14-13-21-35(34)36)45(58)52-39(27-32-17-8-6-9-18-32)44(57)50-37(43(56)54-41)23-12-4-2-3-5-15-25-47/h6-11,13-14,17-22,29,31,37-41,49H,2-5,12,15-16,23-28,30,47-48H2,1H3,(H,50,57)(H,51,59)(H,52,58)(H,53,55)(H,54,56)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
1.00E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
SSTR2


(MOUSE)
BDBM84642
PNG
(SA IV | c[Ahx-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C44H58N8O6/c1-29(58-28-31-17-8-5-9-18-31)39-44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(25-30-15-6-4-7-16-30)42(55)48-35(41(54)52-39)21-10-2-3-13-23-45/h4-9,11-12,15-20,27,29,35-39,47H,2-3,10,13-14,21-26,28,45-46H2,1H3,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
1.00E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
SSTR2


(MOUSE)
BDBM84644
PNG
(III | SA III | c[Aha-Phe-D-Trp-Lys-Ser(Bzl)])
Show SMILES NCCCCCCCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC(=O)C(COCc2ccccc2)NC1=O
Show InChI InChI=1S/C44H58N8O6/c45-23-13-3-1-2-10-21-35-41(54)52-39(29-58-28-31-17-8-5-9-18-31)44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(42(55)48-35)25-30-15-6-4-7-16-30/h4-9,11-12,15-20,27,35-39,47H,1-3,10,13-14,21-26,28-29,45-46H2,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
1.00E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 43: 838-44 (1993)


BindingDB Entry DOI: 10.7270/Q21N7ZN7
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM84642
PNG
(SA IV | c[Ahx-Phe-D-Trp-Lys-Thr(Bzl)])
Show SMILES CC(OCc1ccccc1)C1NC(=O)C(CCCCCCN)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN)NC1=O
Show InChI InChI=1S/C44H58N8O6/c1-29(58-28-31-17-8-5-9-18-31)39-44(57)49-36(22-14-24-46)40(53)51-38(26-32-27-47-34-20-12-11-19-33(32)34)43(56)50-37(25-30-15-6-4-7-16-30)42(55)48-35(41(54)52-39)21-10-2-3-13-23-45/h4-9,11-12,15-20,27,29,35-39,47H,2-3,10,13-14,21-26,28,45-46H2,1H3,(H,48,55)(H,49,57)(H,50,56)(H,51,53)(H,52,54)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
1.00E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by PDSP Ki Database




Mol Pharmacol 44: 385-92 (1993)


BindingDB Entry DOI: 10.7270/Q2X065KZ
More data for this
Ligand-Target Pair