Compounds in cluster

12 similar compounds to monomer 50108392

Wt: 284.3 BDBM91594 Purchase	Wt: 324.3 BDBM50451546 Purchase	Wt: 298.3 BDBM50000495	Wt: 296.3 BDBM50004290	Wt: 284.3 BDBM50007871 Purchase
Wt: 299.3 BDBM50096712	Wt: 324.3 BDBM50131427 Purchase	Wt: 300.3 BDBM50170583	Wt: 284.3 BDBM50181840	Wt: 324.3 BDBM50366823 Purchase
Wt: 298.3 BDBM50391335	Wt: 326.3 BDBM50412171

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 77 hits for monomerid = 91594,50451546,50000495,50004290,50007871,50096712,50131427,50170583,50181840,50366823,50391335,50412171
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
HTR4 (GUINEA PIG)	BDBM50181840 ((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.183	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum				J Med Chem 49: 1125-39 (2006) Article DOI: 10.1021/jm0509501 BindingDB Entry DOI: 10.7270/Q2W096Q0
Pfizer Inc Curated by ChEMBL					More data for this Ligand-Target Pair
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Serotonin (5-HT) receptor (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 267: 961-70 (1993) Article DOI: 10.1016/j.bioorg.2015.05.005 BindingDB Entry DOI: 10.7270/Q2125R5V
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50000495 ((ICS 205-930)1H-Indole-3-carboxylic acid 6-methyl-...) Show SMILES CN1CC2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.				J Med Chem 35: 895-903 (1992) Article DOI: 10.1021/jm00083a014 BindingDB Entry DOI: 10.7270/Q2SJ1M77
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									Psychopharmacology (Berl) 124: 57-73 (1996) Article DOI: 10.1007/bf02245606 BindingDB Entry DOI: 10.7270/Q2610XV6
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Serotonin (5-HT) receptor (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de pharmacologie-endocrinologie (Montpellier, France) Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 345: 264-9 (1992) Article DOI: 10.1007/bf00168685 BindingDB Entry DOI: 10.7270/Q2P55KZ1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50181840 ((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Displacement of [3H]GR65630 from 5HT3 receptor in brain cortex from Wistar rat				J Med Chem 49: 1125-39 (2006) Article DOI: 10.1021/jm0509501 BindingDB Entry DOI: 10.7270/Q2W096Q0
Pfizer Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-7 subunit (Mus musculus)	BDBM50096712 (3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description In vitro Binding affinity towards alpha-7 nAChR was determined				Bioorg Med Chem Lett 11: 319-21 (2001) Article DOI: 10.1016/s0960-894x(00)00670-3 BindingDB Entry DOI: 10.7270/Q2028S36
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50004290 (CHEMBL147262 \| Quinoline-4-carboxylic acid 8-methy...) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1ccnc2ccccc12 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.				J Med Chem 35: 4893-902 (1992) Article DOI: 10.1021/jm00104a016 BindingDB Entry DOI: 10.7270/Q2BK1CZ2
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
HTR3A (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 267: 961-70 (1993) Article DOI: 10.1016/j.bioorg.2015.05.005 BindingDB Entry DOI: 10.7270/Q2125R5V
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
HTR4 (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd. Curated by PDSP K_i Database									Br J Pharmacol 109: 618-24 (1993) Article DOI: 10.1111/j.1476-5381.1993.tb13617.x BindingDB Entry DOI: 10.7270/Q2CZ35PV
Glaxo Group Research Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd. Curated by PDSP K_i Database									Br J Pharmacol 109: 618-24 (1993) Article DOI: 10.1111/j.1476-5381.1993.tb13617.x BindingDB Entry DOI: 10.7270/Q2CZ35PV
Glaxo Group Research Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
University of Oslo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	87.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									FEBS Lett 398: 19-25 (1996) Article DOI: 10.1016/s0014-5793(96)01132-5 BindingDB Entry DOI: 10.7270/Q228065Q
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Acetylcholine Binding protein (Aplysia Californica)	BDBM91594 (Tropisetron) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar	Purchase KEGG PC cid PC sid UniChem Patents Similars		109	-9.33	n/a	n/a	n/a	n/a	n/a	7.4	20
UC San Diego					Assay Description Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...				Taylor Research Group (2014) BindingDB Entry DOI: 10.7270/Q2DR2T3Z
UC San Diego					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									FEBS Lett 398: 19-25 (1996) Article DOI: 10.1016/s0014-5793(96)01132-5 BindingDB Entry DOI: 10.7270/Q228065Q
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
University of Oslo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	159	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Eur J Pharmacol 304: 231-5 (1996) Article DOI: 10.1016/0014-2999(96)00122-7 BindingDB Entry DOI: 10.7270/Q2CN72FW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	544	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Eur J Pharmacol 304: 231-5 (1996) Article DOI: 10.1016/0014-2999(96)00122-7 BindingDB Entry DOI: 10.7270/Q2CN72FW
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	544	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									EMBO J 14: 2806-15 (1995) BindingDB Entry DOI: 10.7270/Q2BK19VW
					More data for this Ligand-Target Pair
Cholinergic, Nicotinic Alpha3Beta2 (Homo sapiens (Human))	BDBM50096712 (3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description In vitro Binding affinity towards alpha-3 (PC12) nAChR was determined				Bioorg Med Chem Lett 11: 319-21 (2001) Article DOI: 10.1016/s0960-894x(00)00670-3 BindingDB Entry DOI: 10.7270/Q2028S36
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
HTR2B (BOVINE)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by PDSP K_i Database									J Neurosci 9: 3482-90 (1989) BindingDB Entry DOI: 10.7270/Q2FX77Z2
Stanford University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha chain/beta chain/delta chain /gamma chain (Homo sapiens (Human))	BDBM50096712 (3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined				Bioorg Med Chem Lett 11: 319-21 (2001) Article DOI: 10.1016/s0960-894x(00)00670-3 BindingDB Entry DOI: 10.7270/Q2028S36
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
HTR3A (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 267: 961-70 (1993) Article DOI: 10.1016/j.bioorg.2015.05.005 BindingDB Entry DOI: 10.7270/Q2125R5V
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	5.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50096712 (3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined				Bioorg Med Chem Lett 11: 319-21 (2001) Article DOI: 10.1016/s0960-894x(00)00670-3 BindingDB Entry DOI: 10.7270/Q2028S36
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by PDSP K_i Database									J Neurosci 9: 3482-90 (1989) BindingDB Entry DOI: 10.7270/Q2FX77Z2
Stanford University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Medical College Curated by PDSP K_i Database									J Neurochem 53: 465-71 (1989) Article DOI: 10.1111/j.1471-4159.1989.tb07357.x BindingDB Entry DOI: 10.7270/Q20000K7
Albany Medical College Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR1D (Bos taurus (Bovine))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Medical College Curated by PDSP K_i Database									J Neurochem 53: 465-71 (1989) Article DOI: 10.1111/j.1471-4159.1989.tb07357.x BindingDB Entry DOI: 10.7270/Q20000K7
Albany Medical College Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by PDSP K_i Database									Biochem Biophys Res Commun 184: 752-9 (1992) Article DOI: 10.1016/0006-291x(92)90654-4 BindingDB Entry DOI: 10.7270/Q2ST7NB1
					More data for this Ligand-Target Pair
HTR3A (GUINEA PIG)	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 267: 961-70 (1993) Article DOI: 10.1016/j.bioorg.2015.05.005 BindingDB Entry DOI: 10.7270/Q2125R5V
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seattle Veterans Affairs Medical Center Curated by PDSP K_i Database									Mol Pharmacol 40: 143-8 (1991) BindingDB Entry DOI: 10.7270/Q26T0K4K
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
U. 109 Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 90: 8547-51 (1993) Article DOI: 10.1073/pnas.90.18.8547 BindingDB Entry DOI: 10.7270/Q29Z93D3
U. 109 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50007871 (CHEMBL8197 \| ICS 205-930 \| TROPISETRON) Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair

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