Wt: 372.5 BDBM92326 ![]() | Wt: 316.4 BDBM50025340 ![]() | Wt: 442.6 BDBM50025377 ![]() | Wt: 371.5 BDBM50025366 ![]() | Wt: 357.5 BDBM50025451 ![]() |
Wt: 357.5 BDBM50025338 ![]() | Wt: 400.5 BDBM50025423 ![]() | Wt: 367.4 BDBM50025422 ![]() | Wt: 372.5 BDBM50025356 ![]() | Wt: 344.4 BDBM50034131 ![]() |
Wt: 330.4 BDBM50034136 ![]() | Wt: 413.6 BDBM50037911 ![]() | Wt: 399.6 BDBM50037925 ![]() | Wt: 385.6 BDBM50037932 ![]() | Wt: 372.5 BDBM50421735 ![]() |
Displayed 1 to 15 (of 22 total ) | Next | Last >> |
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM92326![]() (Finasteride, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | 6.5 | 37 |
National University of Mexico City | Assay Description The IC50 values for the synthesized steroids with human prostate 5alpha-reductase enzyme. | J Enzyme Inhib Med Chem 24: 655-62 (2009) Article DOI: 10.1080/14756360802323720 BindingDB Entry DOI: 10.7270/Q2ZK5F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Rattus norvegicus) | BDBM50025423![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50421735![]() (CHEMBL590709) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Inc. Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after preincubation for 10 minutes | J Med Chem 36: 4313-5 (1994) Article DOI: 10.1021/jm00078a022 BindingDB Entry DOI: 10.7270/Q2PK0F76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Inc. Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after preincubation for 10 minutes | J Med Chem 36: 4313-5 (1994) Article DOI: 10.1021/jm00078a022 BindingDB Entry DOI: 10.7270/Q2PK0F76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence Curated by ChEMBL | Assay Description Inhibitory concentration against human recombinant steroid 5-alpha-reductase type 2 in stably transfected chinese hamster ovary 1827 cells using [3H]... | J Med Chem 47: 3546-60 (2004) Article DOI: 10.1021/jm031131o BindingDB Entry DOI: 10.7270/Q24J0DKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 911 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence Curated by ChEMBL | Assay Description Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin... | J Med Chem 47: 3546-60 (2004) Article DOI: 10.1021/jm031131o BindingDB Entry DOI: 10.7270/Q24J0DKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Canterbury Curated by ChEMBL | Assay Description Inhibition of steroid 5alpha reductase type 2 expressed in HEK 293 cells | Bioorg Med Chem Lett 17: 3603-7 (2007) Article DOI: 10.1016/j.bmcl.2007.04.049 BindingDB Entry DOI: 10.7270/Q2P84BKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 453 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Canterbury Curated by ChEMBL | Assay Description Inhibition of steroid 5alpha reductase type 1 expressed in HEK 293 cells | Bioorg Med Chem Lett 17: 3603-7 (2007) Article DOI: 10.1016/j.bmcl.2007.04.049 BindingDB Entry DOI: 10.7270/Q2P84BKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against type-2 human steroid 5-alpha-reductase. | Bioorg Med Chem Lett 6: 481-484 (1996) Article DOI: 10.1016/0960-894X(96)00054-6 BindingDB Entry DOI: 10.7270/Q2BZ661K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against type-1 human steroid 5-alpha-reductase. | Bioorg Med Chem Lett 6: 481-484 (1996) Article DOI: 10.1016/0960-894X(96)00054-6 BindingDB Entry DOI: 10.7270/Q2BZ661K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Rattus norvegicus) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its inhibitory potency against rat Steroid 5-alpha-reductase type 1 expressed in transformed yeast Saccharomyces cerevesiae | Bioorg Med Chem Lett 6: 1997-2002 (1996) Article DOI: 10.1016/0960-894X(96)00360-5 BindingDB Entry DOI: 10.7270/Q2K0748S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50025340![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50025366![]() (1,4a,6a-Trimethyl-7-(2-methyl-butyryl)-1,4a,4b,5,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50025377![]() (1,4a,6a-Trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50025422![]() (CHEMBL3349157 | CHEMBL76221 | Sodium; 2-(4a,6a-dim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50025423![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50025338![]() (4a,6a-Dimethyl-7-(2-methyl-butyryl)-1,4a,4b,5,6,6a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50025451![]() (4a,6a-Dimethyl-7-(3-methyl-butyryl)-1,4a,4b,5,6,6a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50034131![]() (CHEMBL17025 | N-Methyl-N-((4aR,6aS,7S,11aR)-1,4a,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human steroid 5-alpha-reductase type 2 in SW-13-transfected cells | J Med Chem 38: 1158-73 (1995) Article DOI: 10.1021/jm00007a013 BindingDB Entry DOI: 10.7270/Q2NG4R90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50037911![]() ((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-1,4a,6a,10-te...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of type 2 steroid-5-alpha-reductase | J Med Chem 37: 3871-4 (1994) Article DOI: 10.1021/jm00049a003 BindingDB Entry DOI: 10.7270/Q2K35V8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50037911![]() ((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-1,4a,6a,10-te...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of type 1 steroid-5-alpha-reductase | J Med Chem 37: 3871-4 (1994) Article DOI: 10.1021/jm00049a003 BindingDB Entry DOI: 10.7270/Q2K35V8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50037925![]() ((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a,10-trim...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of type 1 steroid-5-alpha-reductase | J Med Chem 37: 3871-4 (1994) Article DOI: 10.1021/jm00049a003 BindingDB Entry DOI: 10.7270/Q2K35V8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50037925![]() ((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a,10-trim...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 298 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of type 2 steroid-5-alpha-reductase | J Med Chem 37: 3871-4 (1994) Article DOI: 10.1021/jm00049a003 BindingDB Entry DOI: 10.7270/Q2K35V8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50037932![]() ((4aR,6aR)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-1,...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of type 1 steroid-5-alpha-reductase | J Med Chem 37: 3871-4 (1994) Article DOI: 10.1021/jm00049a003 BindingDB Entry DOI: 10.7270/Q2K35V8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50034131![]() (CHEMBL17025 | N-Methyl-N-((4aR,6aS,7S,11aR)-1,4a,6...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cells | J Med Chem 38: 1158-73 (1995) Article DOI: 10.1021/jm00007a013 BindingDB Entry DOI: 10.7270/Q2NG4R90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50034136![]() (CHEMBL277563 | N-((4aR,6aS,7S,11aR)-4a,6a-Dimethyl...) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cells | J Med Chem 38: 1158-73 (1995) Article DOI: 10.1021/jm00007a013 BindingDB Entry DOI: 10.7270/Q2NG4R90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50034136![]() (CHEMBL277563 | N-((4aR,6aS,7S,11aR)-4a,6a-Dimethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human steroid 5-alpha-reductase type 2 in SW-13-transfected cells | J Med Chem 38: 1158-73 (1995) Article DOI: 10.1021/jm00007a013 BindingDB Entry DOI: 10.7270/Q2NG4R90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Rattus norvegicus) | BDBM50421735![]() (CHEMBL590709) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Rattus norvegicus) | BDBM50025451![]() (4a,6a-Dimethyl-7-(3-methyl-butyryl)-1,4a,4b,5,6,6a...) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid 5-alpha-reductase (Rattus norvegicus) | BDBM50025366![]() (1,4a,6a-Trimethyl-7-(2-methyl-butyryl)-1,4a,4b,5,6...) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase | J Med Chem 29: 2298-315 (1986) Article DOI: 10.1021/jm00161a028 BindingDB Entry DOI: 10.7270/Q2XG9RQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-alpha-Reductase (5α-Reductase) (Homo sapiens (Human)) | BDBM50025356![]() (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Metropolitan University-Xochimilco | Assay Description The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3... | J Enzyme Inhib Med Chem 26: 712-9 (2011) Article DOI: 10.3109/14756366.2010.548330 BindingDB Entry DOI: 10.7270/Q25719XS | |||||||||||
More data for this Ligand-Target Pair |