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2 similar compounds to monomer 50271621

Compile data set for download or QSAR
Wt: 469.4
BDBM94333
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Wt: 344.3
BDBM50370335

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 94333,50370335   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50370335
PNG
(CHEMBL1202895)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C17H23F3N2O2/c1-3-14(4-2)21-9-11-22(12-10-21)16(23)13-5-7-15(8-6-13)24-17(18,19)20/h5-8,14H,3-4,9-12H2,1-2H3
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
93n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay


J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair
Chain A, Crystal Structure Of The B1b2 Domains From Human Neuropilin- 1


(Homo sapiens (Human))
BDBM94333
PNG
(3-(difluoromethoxy)-N-[2-[4-[3-(difluoromethoxy)be...)
Show SMILES FC(F)Oc1cccc(c1)C(=O)NCCN1CCN(CC1)C(=O)c1cccc(OC(F)F)c1
Show InChI InChI=1S/C22H23F4N3O4/c23-21(24)32-17-5-1-3-15(13-17)19(30)27-7-8-28-9-11-29(12-10-28)20(31)16-4-2-6-18(14-16)33-22(25)26/h1-6,13-14,21-22H,7-12H2,(H,27,30)
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>9.50E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2HM5725
More data for this
Ligand-Target Pair