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There are 144 purchasable compounds for target: Eukaryotic translation initiation factor 4H

Compile data set for download or QSAR
Wt: 283.3
BDBM2282
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Wt: 354.3
BDBM31699
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Wt: 351.4
BDBM34577
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Wt: 482.5
BDBM41451
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Wt: 445.4
BDBM40089
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Wt: 313.3
BDBM40091
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Wt: 404.4
BDBM44753
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Wt: 437.4
BDBM48414
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Wt: 406.7
BDBM48833
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Wt: 333.3
BDBM51503
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Wt: 356.3
BDBM50578
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Wt: 304.3
BDBM53193
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Wt: 294.3
BDBM52111
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Wt: 485.4
BDBM54943
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Wt: 494.9
BDBM58989
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Displayed 1 to 15 (of 144 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 2282,31699,34577,41451,40089,40091,44753,48414,48833,51503,50578,53193,52111,54943,58989   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM34577
PNG
(3-(benzylamino)-7-ethyl-1-(2-hydroxyethylamino)-6,...)
Show SMILES CCN1CCc2c(C1)c(NCCO)nc(NCc1ccccc1)c2C#N
Show InChI InChI=1S/C20H25N5O/c1-2-25-10-8-16-17(12-21)19(23-13-15-6-4-3-5-7-15)24-20(18(16)14-25)22-9-11-26/h3-7,26H,2,8-11,13-14H2,1H3,(H2,22,23,24)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


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Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM2282
PNG
(5Cl3PhS-2IndolCONH2 inhibitor 9a | cid_454848 | me...)
Show SMILES COC(=O)c1[nH]c2ccccc2c1Sc1ccccc1
Show InChI InChI=1S/C16H13NO2S/c1-19-16(18)14-15(20-11-7-3-2-4-8-11)12-9-5-6-10-13(12)17-14/h2-10,17H,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

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Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2902274
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM51503
PNG
(2-[8-(diethylaminomethyl)-7-hydroxy-2-keto-4-methy...)
Show SMILES CCN(CC)Cc1c(O)ccc2c(C)c(CC(=O)OC)c(=O)oc12
Show InChI InChI=1S/C18H23NO5/c1-5-19(6-2)10-14-15(20)8-7-12-11(3)13(9-16(21)23-4)18(22)24-17(12)14/h7-8,20H,5-6,9-10H2,1-4H3
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n/an/a 1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

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Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM41451
PNG
(MLS000053466 | N-[1-(1H-benzimidazol-2-yl)-2-pheny...)
Show SMILES O=C(NC(Cc1ccccc1)c1nc2ccccc2[nH]1)C1CN(C(=O)C1)c1ccc2OCCOc2c1
Show InChI InChI=1S/C28H26N4O4/c33-26-15-19(17-32(26)20-10-11-24-25(16-20)36-13-12-35-24)28(34)31-23(14-18-6-2-1-3-7-18)27-29-21-8-4-5-9-22(21)30-27/h1-11,16,19,23H,12-15,17H2,(H,29,30)(H,31,34)
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n/an/a 5.62E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM31699
PNG
((4-methoxy-1,3-benzothiazol-2-yl)-[5-(4-methoxyphe...)
Show SMILES COc1ccc(cc1)-c1nnc(Nc2nc3c(OC)cccc3s2)o1
Show InChI InChI=1S/C17H14N4O3S/c1-22-11-8-6-10(7-9-11)15-20-21-16(24-15)19-17-18-14-12(23-2)4-3-5-13(14)25-17/h3-9H,1-2H3,(H,18,19,21)
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n/an/a 1.25E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM40091
PNG
(6-(2-furanyl)-3-methyl-4-oxo-1,5,6,7-tetrahydroind...)
Show SMILES C\C=C\COC(=O)c1[nH]c2CC(CC(=O)c2c1C)c1ccco1
Show InChI InChI=1/C18H19NO4/c1-3-4-7-23-18(21)17-11(2)16-13(19-17)9-12(10-14(16)20)15-6-5-8-22-15/h3-6,8,12,19H,7,9-10H2,1-2H3/b4-3+
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n/an/a 2.17E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM48414
PNG
(4-[[3-keto-2-(4-methoxyphenyl)isoindoline-4-carbon...)
Show SMILES CCOC(=O)N1CCC(CC1)NC(=O)c1cccc2CN(C(=O)c12)c1ccc(OC)cc1
Show InChI InChI=1S/C24H27N3O5/c1-3-32-24(30)26-13-11-17(12-14-26)25-22(28)20-6-4-5-16-15-27(23(29)21(16)20)18-7-9-19(31-2)10-8-18/h4-10,17H,3,11-15H2,1-2H3,(H,25,28)
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n/an/a 9.51E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM58989
PNG
(MLS000374613 | N-(2-chloranyl-5-morpholin-4-ylsulf...)
Show SMILES Oc1ccc(cc1)N1CCN(CC(=O)Nc2cc(ccc2Cl)S(=O)(=O)N2CCOCC2)CC1
Show InChI InChI=1S/C22H27ClN4O5S/c23-20-6-5-19(33(30,31)27-11-13-32-14-12-27)15-21(20)24-22(29)16-25-7-9-26(10-8-25)17-1-3-18(28)4-2-17/h1-6,15,28H,7-14,16H2,(H,24,29)
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n/an/a 7.22E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM48833
PNG
((5Z)-3-(3-chlorophenyl)-5-(4-hydroxy-3-methoxy-5-n...)
Show SMILES COc1cc(\C=C2/SC(=O)N(C2=O)c2cccc(Cl)c2)cc(c1O)[N+]([O-])=O
Show InChI InChI=1S/C17H11ClN2O6S/c1-26-13-6-9(5-12(15(13)21)20(24)25)7-14-16(22)19(17(23)27-14)11-4-2-3-10(18)8-11/h2-8,21H,1H3/b14-7-
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n/an/a 4.99E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM50578
PNG
(3-[6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl...)
Show SMILES OCC1OC(OC(CCc2ccccc2)CC(O)=O)C(O)C(O)C1O
Show InChI InChI=1S/C17H24O8/c18-9-12-14(21)15(22)16(23)17(25-12)24-11(8-13(19)20)7-6-10-4-2-1-3-5-10/h1-5,11-12,14-18,21-23H,6-9H2,(H,19,20)
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n/an/a 2.36E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM53193
PNG
(4-tert-butyl-N-(5-quinolinyl)benzamide | 4-tert-bu...)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C20H20N2O/c1-20(2,3)15-11-9-14(10-12-15)19(23)22-18-8-4-7-17-16(18)6-5-13-21-17/h4-13H,1-3H3,(H,22,23)
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n/an/a 1.14E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2902274
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM48414
PNG
(4-[[3-keto-2-(4-methoxyphenyl)isoindoline-4-carbon...)
Show SMILES CCOC(=O)N1CCC(CC1)NC(=O)c1cccc2CN(C(=O)c12)c1ccc(OC)cc1
Show InChI InChI=1S/C24H27N3O5/c1-3-32-24(30)26-13-11-17(12-14-26)25-22(28)20-6-4-5-16-15-27(23(29)21(16)20)18-7-9-19(31-2)10-8-18/h4-10,17H,3,11-15H2,1-2H3,(H,25,28)
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n/an/a 6.47E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2902274
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM44753
PNG
(MLS000117135 | N-[3-(2-furyl)-1-methyl-propyl]-3-k...)
Show SMILES COc1ccc(cc1)N1Cc2cccc(C(=O)NC(C)CCc3ccco3)c2C1=O
Show InChI InChI=1S/C24H24N2O4/c1-16(8-11-20-6-4-14-30-20)25-23(27)21-7-3-5-17-15-26(24(28)22(17)21)18-9-12-19(29-2)13-10-18/h3-7,9-10,12-14,16H,8,11,15H2,1-2H3,(H,25,27)
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n/an/a 5.42E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

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Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2902274
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM40089
PNG
(7-[4-(2-furoyl)piperazine-1-carbonyl]-2-(4-methoxy...)
Show SMILES COc1ccc(cc1)N1Cc2cccc(C(=O)N3CCN(CC3)C(=O)c3ccco3)c2C1=O
Show InChI InChI=1S/C25H23N3O5/c1-32-19-9-7-18(8-10-19)28-16-17-4-2-5-20(22(17)25(28)31)23(29)26-11-13-27(14-12-26)24(30)21-6-3-15-33-21/h2-10,15H,11-14,16H2,1H3
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n/an/a 1.43E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

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Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2902274
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM54943
PNG
(4-[[2-[(Z)-[1-[2-(2-methylanilino)-2-oxoethyl]-2,5...)
Show SMILES Cc1ccccc1NC(=O)CN1C(=O)N\C(=C/c2ccccc2OCc2ccc(cc2)C(O)=O)C1=O
Show InChI InChI=1S/C27H23N3O6/c1-17-6-2-4-8-21(17)28-24(31)15-30-25(32)22(29-27(30)35)14-20-7-3-5-9-23(20)36-16-18-10-12-19(13-11-18)26(33)34/h2-14H,15-16H2,1H3,(H,28,31)(H,29,35)(H,33,34)/b22-14-
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n/an/a 7.28E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

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Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2902274
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 4H


(Homo sapiens (Human))
BDBM52111
PNG
(1-phenyl-3-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl...)
Show SMILES CCCSc1nnc(NC(=O)Nc2ccccc2)s1
Show InChI InChI=1S/C12H14N4OS2/c1-2-8-18-12-16-15-11(19-12)14-10(17)13-9-6-4-3-5-7-9/h3-7H,2,8H2,1H3,(H2,13,14,15,17)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


Article DOI: 10.1111/cbdd.12272
BindingDB Entry DOI: 10.7270/Q26W98HW
More data for this
Ligand-Target Pair