BindingDB logo
myBDB logout

There are 207 purchasable compounds for target: Gli1

Compile data set for download or QSAR
Wt: 264.3
BDBM19149
Purchase
Wt: 325.3
BDBM18224
Purchase
Wt: 417.5
BDBM33682
Purchase
Wt: 360.7
BDBM39087
Purchase
Wt: 395.2
BDBM39088
Purchase
Wt: 351.4
BDBM38951
Purchase
Wt: 392.9
BDBM39113
Purchase
Wt: 366.4
BDBM38994
Purchase
Wt: 259.2
BDBM36929
Purchase
Wt: 349.3
BDBM36933
Purchase
Wt: 399.4
BDBM37170
Purchase
Wt: 415.4
BDBM37197
Purchase
Wt: 326.4
BDBM37095
Purchase
Wt: 382.4
BDBM41360
Purchase
Wt: 447.5
BDBM40828
Purchase
Displayed 1 to 15 (of 207 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 19149,18224,33682,39087,39088,38951,39113,38994,36929,36933,37170,37197,37095,41360,40828   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Zinc finger protein GLI1


(Mus musculus)
BDBM39087
PNG
(7-[(4-chlorophenyl)methyl]-1,3-dimethyl-8-prop-2-e...)
Show SMILES Cn1c2nc(OCC=C)n(Cc3ccc(Cl)cc3)c2c(=O)n(C)c1=O
Show InChI InChI=1S/C17H17ClN4O3/c1-4-9-25-16-19-14-13(15(23)21(3)17(24)20(14)2)22(16)10-11-5-7-12(18)8-6-11/h4-8H,1,9-10H2,2-3H3
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 7.97E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM18224
PNG
(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Show SMILES COc1ccc(OC)c(Cc2cnc3nc(N)nc(N)c3c2C)c1
Show InChI InChI=1S/C17H19N5O2/c1-9-11(6-10-7-12(23-2)4-5-13(10)24-3)8-20-16-14(9)15(18)21-17(19)22-16/h4-5,7-8H,6H2,1-3H3,(H4,18,19,20,21,22)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PCBioAssay
n/an/a 2.80E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM36929
PNG
(4-butoxy-8-fluoranyl-5H-pyrimido[5,4-b]indole | 4-...)
Show SMILES CCCCOc1ncnc2c3cc(F)ccc3[nH]c12
Show InChI InChI=1S/C14H14FN3O/c1-2-3-6-19-14-13-12(16-8-17-14)10-7-9(15)4-5-11(10)18-13/h4-5,7-8,18H,2-3,6H2,1H3
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 4.85E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM36933
PNG
(MLS000041708 | N-[2-(3,4-dimethoxyphenyl)ethyl]-4-...)
Show SMILES COc1ccc(CCNc2ncnc3c4ccccc4oc23)cc1OC
Show InChI InChI=1S/C20H19N3O3/c1-24-16-8-7-13(11-17(16)25-2)9-10-21-20-19-18(22-12-23-20)14-5-3-4-6-15(14)26-19/h3-8,11-12H,9-10H2,1-2H3,(H,21,22,23)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 2.72E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM38951
PNG
(2,4-dimethyl-N-(3,4,5-trimethoxyphenyl)benzenesulf...)
Show SMILES COc1cc(NS(=O)(=O)c2ccc(C)cc2C)cc(OC)c1OC
Show InChI InChI=1S/C17H21NO5S/c1-11-6-7-16(12(2)8-11)24(19,20)18-13-9-14(21-3)17(23-5)15(10-13)22-4/h6-10,18H,1-5H3
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 6.71E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM38994
PNG
(MLS000089367 | N-(2-methoxyethyl)-2-[({5-methyl-2-...)
Show SMILES COCCNC(=O)CSCc1nc(oc1C)-c1ccc(SC)cc1
Show InChI InChI=1S/C17H22N2O3S2/c1-12-15(10-24-11-16(20)18-8-9-21-2)19-17(22-12)13-4-6-14(23-3)7-5-13/h4-7H,8-11H2,1-3H3,(H,18,20)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/a 8.46E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM37095
PNG
(4-(6-methyl-5-imidazo[2,1-b]thiazolyl)-N-(phenylme...)
Show SMILES Cc1nc2sccn2c1-c1csc(NCc2ccccc2)n1
Show InChI InChI=1S/C16H14N4S2/c1-11-14(20-7-8-21-16(20)18-11)13-10-22-15(19-13)17-9-12-5-3-2-4-6-12/h2-8,10H,9H2,1H3,(H,17,19)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/a 9.83E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM39113
PNG
(MLS000066583 | N-(3-chloranyl-4-morpholin-4-yl-phe...)
Show SMILES Cc1cc(C)nc(SCC(=O)Nc2ccc(N3CCOCC3)c(Cl)c2)n1
Show InChI InChI=1S/C18H21ClN4O2S/c1-12-9-13(2)21-18(20-12)26-11-17(24)22-14-3-4-16(15(19)10-14)23-5-7-25-8-6-23/h3-4,9-10H,5-8,11H2,1-2H3,(H,22,24)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/a 3.52E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM41360
PNG
(MLS000118109 | N-[2-(dipropylamino)ethyl]-1,5-dime...)
Show SMILES CCCN(CCC)CCNC(=O)c1cc2c(n1C)c1ccccc1n(C)c2=O
Show InChI InChI=1S/C22H30N4O2/c1-5-12-26(13-6-2)14-11-23-21(27)19-15-17-20(24(19)3)16-9-7-8-10-18(16)25(4)22(17)28/h7-10,15H,5-6,11-14H2,1-4H3,(H,23,27)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a>2.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM37170
PNG
(3-methyl-4-oxo-6-(3,4,5-trimethoxyphenyl)-1,5,6,7-...)
Show SMILES COc1cc(cc(OC)c1OC)C1Cc2[nH]c(C(=O)OCC=C)c(C)c2C(=O)C1
Show InChI InChI=1/C22H25NO6/c1-6-7-29-22(25)20-12(2)19-15(23-20)8-13(9-16(19)24)14-10-17(26-3)21(28-5)18(11-14)27-4/h6,10-11,13,23H,1,7-9H2,2-5H3
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 1.98E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM33682
PNG
(MLS000324904 | N-(3b,4,5,6,6a,7,9,9a,10,11,12,12a-...)
Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)Nc1cc2C3CCCC3CN3CC4CCCC4c(c1)c23
Show InChI InChI=1S/C25H27N3O3/c29-25(15-7-9-19(10-8-15)28(30)31)26-18-11-22-20-5-1-3-16(20)13-27-14-17-4-2-6-21(17)23(12-18)24(22)27/h7-12,16-17,20-21H,1-6,13-14H2,(H,26,29)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/a 5.09E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM37197
PNG
(3-methyl-4-oxo-6-(3,4,5-trimethoxyphenyl)-1,5,6,7-...)
Show SMILES CCCCOC(=O)c1[nH]c2CC(CC(=O)c2c1C)c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1/C23H29NO6/c1-6-7-8-30-23(26)21-13(2)20-16(24-21)9-14(10-17(20)25)15-11-18(27-3)22(29-5)19(12-15)28-4/h11-12,14,24H,6-10H2,1-5H3
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 2.22E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM40828
PNG
(3-(1-azepanylsulfonyl)-N-(4-thiophen-2-yl-2-thiazo...)
Show SMILES O=C(Nc1nc(cs1)-c1cccs1)c1cccc(c1)S(=O)(=O)N1CCCCCC1
Show InChI InChI=1S/C20H21N3O3S3/c24-19(22-20-21-17(14-28-20)18-9-6-12-27-18)15-7-5-8-16(13-15)29(25,26)23-10-3-1-2-4-11-23/h5-9,12-14H,1-4,10-11H2,(H,21,22,24)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 2.28E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

CHEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PCBioAssay
n/an/a 2.23E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM39088
PNG
(7-[(2,4-dichlorophenyl)methyl]-1,3-dimethyl-8-prop...)
Show SMILES Cn1c2nc(OCC=C)n(Cc3ccc(Cl)cc3Cl)c2c(=O)n(C)c1=O
Show InChI InChI=1S/C17H16Cl2N4O3/c1-4-7-26-16-20-14-13(15(24)22(3)17(25)21(14)2)23(16)9-10-5-6-11(18)8-12(10)19/h4-6,8H,1,7,9H2,2-3H3
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 1.03E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 19149,18224,33682,39087,39088,38951,39113,38994,36929,36933,37170,37197,37095,41360,40828
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
Histone deacetylase 1/3/5/8

(Homo sapiens (Human))
BDBM19149
JPEG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
GoogleScholar
PDB
CHEBI
DrugBank
MMDB
PC cid
PC sid
PDB
-8.362.42-10.96.13n/a25



North Dakota State University





Biochemistry 52: 8139-49 (2013)

Histone deacetylase 8 (HDAC8)

(Homo sapiens (Human))
BDBM19149
JPEG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
GoogleScholar
PDB
CHEBI
DrugBank
MMDB
PC cid
PC sid
PDB
-8.360.0519-8.966.347.5-248



North Dakota State University





Biochemistry 53: 7445-58 (2014)