Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAromatase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50197078(CHEMBL3977491)Copy SMILESCopy InChI

Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant human microsomal CYP19 using MFC as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEstrogen receptor(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50197078(CHEMBL3977491)Copy SMILESCopy InChI

Affinity DataEC50:  1.10E+4nMAssay Description:Displacement of fluorescent ES2 from recombinant human ERalpha after 2 hrs in absence of light by fluorometric analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEstrogen receptor beta(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50197078(CHEMBL3977491)Copy SMILESCopy InChI

Affinity DataEC50:  857nMAssay Description:Displacement of fluorescent ES2 from recombinant human ERbeta after 2 hrs in absence of light by fluorometric analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI