Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322786(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322786(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322786(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of CYP3A4 expressed in baculovirus infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322786(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
Affinity DataIC50:  7.18E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322786(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
Affinity DataIC50:  4.95E+4nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed