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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Steroid 17-alpha-hydroxylase/17,20 lyase
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322786
(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
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Affinity Data
IC50: 75nM
Assay Description:
Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322786
(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
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Affinity Data
IC50: 1.13E+3nM
Assay Description:
Inhibition of human CYP11B2 expressed in hamster V79MZh cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322786
(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
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Affinity Data
IC50: 1.77E+3nM
Assay Description:
Inhibition of CYP3A4 expressed in baculovirus infected insect microsomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322786
(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
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Affinity Data
IC50: 7.18E+3nM
Assay Description:
Inhibition of human CYP11B1 expressed in hamster V79MZh cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Aromatase
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322786
(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)
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Affinity Data
IC50: 4.95E+4nM
Assay Description:
Inhibition of CYP19 in human placental microsomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI