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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cell lysates after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
R.C. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50:  0.00100nMAssay Description:Inhibition of mouse brain MAO-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Mus musculus)
R.C. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50:  0.0350nMAssay Description:Inhibition of mouse brain MAO-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
R.C. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50:  600nMAssay Description:Inhibition of mouse MAO-B preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9(Homo sapiens)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9(Homo sapiens)
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50:  2.39E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50:  3.45E+5nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed