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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataKi:  37nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataKi:  1.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataIC50:  0.220nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Sinhgad College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of Candida albicans OSCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataIC50:  50nMAssay Description:Inhibition of rat OSCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataIC50:  50nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataIC50:  2.30E+3nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed