Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAromatase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50081466(CHEMBL3422030)Copy SMILESCopy InChI

Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-trifluoromethylcoumarin as substrate assessed as formation of fluorescent metabolite after ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEstrogen receptor beta(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50081466(CHEMBL3422030)Copy SMILESCopy InChI

Affinity DataEC50:  202nMAssay Description:Displacement of fluorescein-labeled ES2 from human recombinant ERbeta receptor after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEstrogen receptor(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

LigandBDBM50081466(CHEMBL3422030)Copy SMILESCopy InChI

Affinity DataEC50:  277nMAssay Description:Displacement of fluorescein-labeled ES2 from human recombinant ERalpha receptor after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI