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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50300673
(2-(6-{[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...)
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Affinity Data
Ki: 4.10nM
Assay Description:
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50300673
(2-(6-{[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...)
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Copy InChI
Affinity Data
IC50: 54nM
Assay Description:
Antagonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as inhibition of 5HT-stimulated cAMP production after 30 mins by HTRF ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50300673
(2-(6-{[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...)
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Copy InChI
Affinity Data
IC50: >1.00E+3nM
Assay Description:
Inhibition of human 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI