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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Alpha-1A adrenergic receptor
(CALF)
TBA
Curated by
ChEMBL
Ligand
BDBM50026967
(11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethy...)
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Affinity Data
Ki: 13nM
Assay Description:
Displacement of [3H]- prazosin radioligand binding at the alpha 1-adrenergic binding site of calf cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50026967
(11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethy...)
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Affinity Data
Ki: 17nM
Assay Description:
Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1A/1B/1D/1F
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50026967
(11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethy...)
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Affinity Data
Ki: 24nM
Assay Description:
Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50026967
(11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethy...)
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Affinity Data
Ki: 88nM
Assay Description:
Displacement of [3H]- QNB binding at the muscarinic-cholinergic binding site of rat brain S1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50026967
(11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethy...)
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Copy InChI
Affinity Data
Ki: 180nM
Assay Description:
Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM50026967
(11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethy...)
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Affinity Data
Ki: 230nM
Assay Description:
Displacement of [3H]- clonidine radioligand binding at the alpha-2 adrenergic receptor binding site of calf cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI