Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50382925(CHEMBL2029398)Copy SMILESCopy InChI

Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of human recombinant neprilysin using Abz-dR-G-L-EDDnp as substrate incubated for 10 mins prior to substrate addition measured for 40 mins...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAminopeptidase N(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50382925(CHEMBL2029398)Copy SMILESCopy InChI

Affinity DataIC50:  1.22E+5nMAssay Description:Inhibition of human recombinant aminopeptidase N using Ala-Mca as substrate incubated for 10 mins prior to substrate addition measured for 40 mins by...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI