Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL

LigandBDBM50154560(CHEMBL3775118)Copy SMILESCopy InChI

Affinity DataIC50:  3.99E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair

Target InfoNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL

LigandBDBM50154560(CHEMBL3775118)Copy SMILESCopy InChI

Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI