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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50018794
(CHEMBL3291340)
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50018794
(CHEMBL3291340)
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Affinity Data
IC50: 16nM
Assay Description:
Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50018794
(CHEMBL3291340)
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Copy InChI
Affinity Data
IC50: 7.70E+3nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI