Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50204272(CHEMBL3964139)Copy SMILESCopy InChI

Affinity DataIC50:  27nMAssay Description:Inhibition of human ROMK expressed in CHO cells after 6 mins at -70 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50204272(CHEMBL3964139)Copy SMILESCopy InChI

Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human ERG by electrophysiology methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI