Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL

LigandBDBM50140179(CHEMBL3753748)Copy SMILESCopy InChI

Affinity DataIC50:  15nMAssay Description:Binding affinity to integrin alpha5/beta1 heterodimer in human K562 cells assessed as inhibition of integrin-mediated human K562 cell adhesion to fib...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL

LigandBDBM50140179(CHEMBL3753748)Copy SMILESCopy InChI

Affinity DataIC50:  34nMAssay Description:Binding affinity to integrin alphav/beta3 heterodimer in human M21 cells assessed as inhibition of integrin-mediated human M21 cell adhesion to vitro...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI