Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Genentech

LigandBDBM17348((3R,6S,9aS)-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-...)Copy SMILESCopy InChI

Affinity DataKi:  3.00E+3nM ΔG°:  -31.2kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetComplex of Baculoviral IAP repeat-containing protein 7 [1-159,S150G] and E3 ubiquitin-protein ligase XIAP [336-348](Homo sapiens (Human))
Genentech

LigandBDBM17348((3R,6S,9aS)-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-...)Copy SMILESCopy InChI

Affinity DataKi:  4.19E+3nM ΔG°:  -30.4kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI