Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Acetylpolyamine amidohydrolase
(Mycoplana ramosa (Gram-negative bacterium))
University Of Pennsylvania
Ligand
BDBM152731
(8-Amino-N-hydroxypentanamide (7))
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
pH: 8.2
Assay Description:
Activity assays were conducted at 25 °C and contained 250 nM APAH (∼50% Zn2+ occupancy), 150 μM substrate, and 0−250 μM inhibit...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
University Of Pennsylvania
Ligand
BDBM152731
(8-Amino-N-hydroxypentanamide (7))
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.20E+3nM
pH: 8.2
Assay Description:
Activity assays were conducted at 25 °C and contained 500 nM HDAC8 enzyme, 150 μM Ac-Arg-His-Lys(Ac)-Lys(Ac)-aminomethylcoumarin substrate (BML-...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI