Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50088804(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)
Affinity DataKi:  37nMAssay Description:Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target4-hydroxyphenylpyruvate dioxygenase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50088804(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50088804(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Wistar rat liver HPPD using 4-Hydroxyphenylpyruvate as substrate assessed as reduction in oxygen consumption preincubated for 3 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Tunghai Christian University

Curated by ChEMBL
LigandPNGBDBM50088804(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of 4-hydroxyphenylpyruvate dioxygenase of purified pig liver by enol-borate methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed