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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Acelot

Curated by ChEMBL
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataIC50:  450nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Acelot

Curated by ChEMBL
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataIC50:  500nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Acelot

Curated by ChEMBL
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Acelot

Curated by ChEMBL
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of wild type LRRK2 (unknown origin) assessed as inhibition of LRRKtide phosphorylation after 120 mins by radiometric assay in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Acelot

Curated by ChEMBL
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type pcDNA5FRT-TO-GFP fused - LRRK2 (unknown origin) transfected in HEK293 cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Acelot

Curated by ChEMBL
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of pcDNA5FRT-TO-GFP fused - LRRK2 G2019S mutant (unknown origin) transfected in HEK293 cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed