Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Mcneil Pharmaceutical And Janssen Research Foundation Worldwide
Curated by
ChEMBL
Ligand
BDBM50017449
(1-(3-Nitro-phenyl)-piperazine | CHEMBL267153 | EN3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 34nM
Assay Description:
Binding affinity at rat 5-hydroxytryptamine 1B receptor by [3H]-5-HT displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A/1B/1D/1F
(RAT)
Mcneil Pharmaceutical And Janssen Research Foundation Worldwide
Curated by
ChEMBL
Ligand
BDBM50017449
(1-(3-Nitro-phenyl)-piperazine | CHEMBL267153 | EN3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 250nM
Assay Description:
Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serotonin 2 (5-HT2) receptor
(RAT)
Mcneil Pharmaceutical And Janssen Research Foundation Worldwide
Curated by
ChEMBL
Ligand
BDBM50017449
(1-(3-Nitro-phenyl)-piperazine | CHEMBL267153 | EN3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 419nM
Assay Description:
Binding affinity at rat 5-hydroxytryptamine 2 receptor by [3H]ketanserin displacement.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
Mcneil Pharmaceutical And Janssen Research Foundation Worldwide
Curated by
ChEMBL
Ligand
BDBM50017449
(1-(3-Nitro-phenyl)-piperazine | CHEMBL267153 | EN3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity at rat Dopamine receptor D1 by [3H]-SCH-23,390 displacement.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Mcneil Pharmaceutical And Janssen Research Foundation Worldwide
Curated by
ChEMBL
Ligand
BDBM50017449
(1-(3-Nitro-phenyl)-piperazine | CHEMBL267153 | EN3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity against rat Alpha-1 adrenergic receptor.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Mcneil Pharmaceutical And Janssen Research Foundation Worldwide
Curated by
ChEMBL
Ligand
BDBM50017449
(1-(3-Nitro-phenyl)-piperazine | CHEMBL267153 | EN3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity against rat Dopamine receptor D2.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50017449
(1-(3-Nitro-phenyl)-piperazine | CHEMBL267153 | EN3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity against nicotinic receptors from rat brain using [3H]cystine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Replicase polyprotein 1ab
(2019-nCoV)
Cornell University
Ligand
BDBM50017449
(1-(3-Nitro-phenyl)-piperazine | CHEMBL267153 | EN3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.87E+3nM
Assay Description:
IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI