Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191386((5R)(6Z)-7-oxo-6-(4,5,6,7-tetrahydropyrazolo-[1,5-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191386((5R)(6Z)-7-oxo-6-(4,5,6,7-tetrahydropyrazolo-[1,5-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191386((5R)(6Z)-7-oxo-6-(4,5,6,7-tetrahydropyrazolo-[1,5-...)
Affinity DataIC50:  62nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetImipenem-hydrolyzing beta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191386((5R)(6Z)-7-oxo-6-(4,5,6,7-tetrahydropyrazolo-[1,5-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Enterobacter cloacae Imi1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed