Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL

LigandBDBM50059005(3-(4-Bromo-benzenesulfonyl)-1-phenyl-imidazolidine...)Copy SMILESCopy InChI

Affinity DataIC50:  170nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL

LigandBDBM50059005(3-(4-Bromo-benzenesulfonyl)-1-phenyl-imidazolidine...)Copy SMILESCopy InChI

Affinity DataIC50:  600nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL

LigandBDBM50059005(3-(4-Bromo-benzenesulfonyl)-1-phenyl-imidazolidine...)Copy SMILESCopy InChI

Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI