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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataKi:  9.78E+4nMAssay Description:Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity nicotinic acetylcholine receptor alpha-7 was evaluated by its ability to inhibit [3H]methyllycaconitine ([3H]-MLA) binding to rat br...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataKi:  1.20E+5nMAssay Description:Mixed-type inhibition of horse serum butyrylcholinesterase using acetylcholine bromide as substrate assessed as free enzyme-inhibitor complex by Line...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataKi:  6.20E+5nMAssay Description:Mixed-type inhibition of horse serum butyrylcholinesterase using acetylcholine bromide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataKi:  1.60E+7nMAssay Description:Mixed-type inhibition of electric eel acetylcholinesterase using acetylcholine bromide as substrate assessed as concentration required for 25% inhibi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Military Health Sciences

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Military Health Sciences

Curated by ChEMBL
LigandPNGBDBM50119784(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of human plasma BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed