Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.78E+4nM
Assay Description:
Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Binding affinity nicotinic acetylcholine receptor alpha-7 was evaluated by its ability to inhibit [3H]methyllycaconitine ([3H]-MLA) binding to rat br...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Equus caballus (Horse))
TBA
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.20E+5nM
Assay Description:
Mixed-type inhibition of horse serum butyrylcholinesterase using acetylcholine bromide as substrate assessed as free enzyme-inhibitor complex by Line...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Equus caballus (Horse))
TBA
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.20E+5nM
Assay Description:
Mixed-type inhibition of horse serum butyrylcholinesterase using acetylcholine bromide as substrate by Lineweaver-Burk plot analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60E+7nM
Assay Description:
Mixed-type inhibition of electric eel acetylcholinesterase using acetylcholine bromide as substrate assessed as concentration required for 25% inhibi...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of electric eel AChE by modified Ellman's method
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Equus caballus (Horse))
Friedrich-Schiller-Universitat Jena
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of equine serum BChE by modified Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Military Health Sciences
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.30E+4nM
Assay Description:
Inhibition of human erythrocyte AChE after 5 mins by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Military Health Sciences
Curated by
ChEMBL
Ligand
BDBM50119784
(1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30E+5nM
Assay Description:
Inhibition of human plasma BChE after 5 mins by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI