Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology

LigandBDBM9436(CHEMBL1084096 | Heterodimeric Tacrine-Based Inhibi...)Copy SMILESCopy InChI

Affinity DataIC50:  13.6nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL

LigandBDBM9436(CHEMBL1084096 | Heterodimeric Tacrine-Based Inhibi...)Copy SMILESCopy InChI

Affinity DataIC50:  13.6nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology

LigandBDBM9436(CHEMBL1084096 | Heterodimeric Tacrine-Based Inhibi...)Copy SMILESCopy InChI

Affinity DataIC50:  157nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI