Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50:  120nMAssay Description:Inhibition of anti-CXCR4 12G5 monoclonal antibody to CXCR4 in human SUP-T1 cells pretreated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radiolabeled MCP1 from CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radiolabeled IL8 from CXCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radiolabeled MIP1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radiolabeled IL8 from CXCR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radiolabeled MIP1alpha from CCR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radiolabeled TARC from CCR4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed