Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 12 hits in this display
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Ki: 620nM IC50: 1.00E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Ki: 720nM IC50: 1.40E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Ki: 980nM IC50: 1.00E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Ki: 1.60E+3nM IC50: 4.70E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Ki: 2.60E+3nM IC50: 7.20E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
IC50: 5.90nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
IC50: 1.40E+3nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
BDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
IC50: 6.70E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair