Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Gag-Pol polyprotein
(Human immunodeficiency virus type 1 group M subtyp...)
University Of Pittsburgh
Curated by
PubChem BioAssay
Ligand
BDBM34300
(3-(1-benzotriazolylmethyl)-6-(phenylmethyl)-[1,2,4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.84E+3nM
pH: 8.0 T: 2°C
Assay Description:
A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Histone-lysine N-methyltransferase, H3 lysine-79 specific
(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM34300
(3-(1-benzotriazolylmethyl)-6-(phenylmethyl)-[1,2,4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.94E+4nM
Assay Description:
Inhibition of N-terminal 6His-tagged human DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) at preincubated for 15 mins followed by ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone-lysine N-methyltransferase, H3 lysine-79 specific
(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM34300
(3-(1-benzotriazolylmethyl)-6-(phenylmethyl)-[1,2,4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.88E+4nM
Assay Description:
Inhibition of DOT1L in human MV4-11 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bcl-2-like protein 11
(Homo sapiens (Human))
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM34300
(3-(1-benzotriazolylmethyl)-6-(phenylmethyl)-[1,2,4...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >3.50E+5nM
Assay Description:
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI