Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50400736(CHEMBL2203542)Copy SMILESCopy InChI

Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50400736(CHEMBL2203542)Copy SMILESCopy InChI

Affinity DataIC50:  6.73E+4nMAssay Description:Inhibition of SIRT5 using ZK(suc)A substrate after 1 hr by homogeneous fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI