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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Neprilysin
(Homo sapiens (Human))
Theravance Biopharma R&D Ip
US Patent
Ligand
BDBM298315
((2S,4R)-5-(3'-Fluorobiphenyl-4-yl)-2-hydroxymethyl...)
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Affinity Data
Ki: 3.55nM
Assay Description:
The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Neprilysin
(Homo sapiens (Human))
Theravance Biopharma R&D Ip
US Patent
Ligand
BDBM298315
((2S,4R)-5-(3'-Fluorobiphenyl-4-yl)-2-hydroxymethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.55nM
Assay Description:
The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Neprilysin/Angiotensin-converting enzyme
(Homo sapiens (Human))
Theravance Biopharma R&D Ip
US Patent
Ligand
BDBM298315
((2S,4R)-5-(3'-Fluorobiphenyl-4-yl)-2-hydroxymethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.55nM
Assay Description:
The assays were performed in 384-well white opaque plates at 37? C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Neprilysin/Angiotensin-converting enzyme
(Homo sapiens (Human))
Theravance Biopharma R&D Ip
US Patent
Ligand
BDBM298315
((2S,4R)-5-(3'-Fluorobiphenyl-4-yl)-2-hydroxymethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.55nM
Assay Description:
The assays were performed in 384-well white opaque plates at 37? C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Neprilysin/Angiotensin-converting enzyme
(Homo sapiens (Human))
Theravance Biopharma R&D Ip
US Patent
Ligand
BDBM298315
((2S,4R)-5-(3'-Fluorobiphenyl-4-yl)-2-hydroxymethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.5nM
Assay Description:
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI