Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50168756((2R,3R)-3-Hydroxy-1-[4-(isoquinolin-8-ylmethoxy)-b...)Copy SMILESCopy InChI

Affinity DataIC50:  2.5nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50168756((2R,3R)-3-Hydroxy-1-[4-(isoquinolin-8-ylmethoxy)-b...)Copy SMILESCopy InChI

Affinity DataIC50:  7.80E+3nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI