Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50127450
(CHEMBL51966 | N-Hydroxy-2-(7-hydroxy-1,1-dioxo-1,3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: <2.80nM
Assay Description:
In vitro inhibitory activity against broad spectrum matrix metalloprotease-2 (MMP-2)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50127450
(CHEMBL51966 | N-Hydroxy-2-(7-hydroxy-1,1-dioxo-1,3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 100nM
Assay Description:
In vitro inhibitory activity against broad spectrum matrix metalloprotease-9 (MMP-9)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50127450
(CHEMBL51966 | N-Hydroxy-2-(7-hydroxy-1,1-dioxo-1,3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 391nM
Assay Description:
In vitro inhibitory activity against porcine tumor necrosis factor alpha converting enzyme (pTACE)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50127450
(CHEMBL51966 | N-Hydroxy-2-(7-hydroxy-1,1-dioxo-1,3...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 980nM
Assay Description:
In vitro inhibitory activity against broad spectrum matrix metalloprotease-1 (MMP-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI