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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Merck Research Laboratories
Ligand
BDBM16414
(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)
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Affinity Data
IC50: 14nM
pH: 4.5 T: 2°C
Assay Description:
The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 2
(Homo sapiens (Human))
Merck Research Laboratories
Ligand
BDBM16414
(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)
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Copy InChI
Affinity Data
IC50: 110nM
pH: 4.5 T: 2°C
Assay Description:
The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
Merck Research Laboratories
Ligand
BDBM16414
(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40E+4nM
Assay Description:
Inhibition of BACE1 after 2 hrs by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI